Transcriptomic analysis of the long-lived and short-lived Atg1 over-expressing flies reveals altered immunity and mitochondrial function. by Ivana Bjedov (75652)

“…Data are means ±SEM of n = 3 replicates. Statistical significance was calculated by a one-way ANOVA Tukey-Kramer (HSD) test (*, p<0.05; **, p<0.01; *** p<0.001). …”

Full-length AKAP13 mRNA levels are reduced by the gene-trap events. by Matthew J. Spindler (407529)

“…All three gene-traps decreased expression of the E37-38 exon-exon junction in a dose-dependent manner. …”

ML141 or wiskostatin treatments stimulate CFTR endocytosis. by Romain Ferru-Clément (701878)

“…<p>(A) Representative Western blots and (B and C) histograms summarizing the data are presented. …”

Cell proliferation of BmN4-SID1 cells expressing insect ANTs under knockdown of the endogenous BmANTI1. by Ryohei Sugahara (699858)

“…Error bars represent the SD values of the means of triplicate wells. Differences in cell proliferation rate between BmANTI1-knockdown cells and cells soaked in VENUS dsRNA were evaluated with a two-tailed Student’s <i>t</i>-test. …”

Effects of Circularity Interventions in the European Plastic Packaging Sector by Ciprian Cimpan (16469128)

“…By means of a mixed-unit input–output (IO) model, we performed a comparative scenario analysis for the development of demand and waste management up to 2030 within the EU-28 (EU27 + United Kingdom). …”

Gadolinium-free Magnetic Resonance Imaging of the Liver via an Oatp1-Targeted Manganese(III) Porphyrin by Nivin N. Nyström (13118188)

“…Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their continued utility highly contentious, but the liver-specific GBCA Gd­(III) ethoxybenzyl-diethylene triamine pentaacetic acid (Gd­(III)-EOB-DTPA) remains in use because it provides unique diagnostic information that could not be obtained by any other means. To address the need for an alternate liver-specific MRI probe, we synthesized Mn­(III) 20-(4-ethoxyphenyl) porphyrin-5,10,15-tricarboxylate (Mn­(III)­TriCP-PhOEt), which exhibited significantly higher <i>r</i>₁ relaxivity than Gd­(III)-EOB-DTPA in vitro, while also targeting hepatocyte-specific organic anion-transporting polypeptide 1 (Oatp1) channels as a marker of viability. …”

Variability of Coastal and Ocean Water Temperature in the Upper 700 m along the Western Iberian Peninsula from 1975 to 2006 by Fran Santos (113729)

“…The analysis was carried out by means of the Simple Ocean Data Assimilation (SODA). …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. …”

Comparison of SPTAN1 in MLH1-proficient vs. MLH1-deficient CRCs. by Anne Ackermann (6443975)

“…SPTAN1 was significantly increased in MLH1-proficient tumors compared with the normal mucosa, while MLH1-deficient tumors showed a clear trend of decreased SPTAN1 levels compared with surrounding normal tissue. …”

Enforced expression of Mfn2 and DRP1 relieves Vpr-induced apoptosis. by Chih-Yang Huang (54970)

“…<b>D,</b> Overexpression of Mfn2, DRP1, and Mfn2/DRP1 reduced Vpr-induced apoptosis. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033657#s2" target="_blank">Results</a> are the means ± S.D. of three independent experiments. …”

<b>Pirani Gauge: Function, Calibration, and Use in Pharmaceutical Freeze-Drying</b> by Geoff Smith (6064268)

“…During freeze-drying, this results in <b>higher readings while ice is sublimating</b>, and the signal decreases as sublimation slows. Importantly, the <b>end of ice sublimation can occur during (but often around the midpoint) of the step-down in the Pirani signal</b>, meaning the gauge alone cannot precisely identify the sublimation endpoint. …”

Cardiac function of hearts expressing control PolyQ-25 and mutant PolyQ-46 affected differently by oxidant. by Girish C. Melkani (213588)

“…<p>(<b>A & B</b>) The already large systolic and diastolic heart diameters were further increased in the presence of the oxidant H₂O₂ in the hearts expressing PolyQ-46. …”

Genome-Wide Patterns of Gene Expression during Aging in the African Malaria Vector <em>Anopheles gambiae</em> by Mei-Hui Wang (203053)

“…<div><p>The primary means of reducing malaria transmission is through reduction in longevity in days of the adult female stage of the <em>Anopheles</em> vector. …”

T cell survival is regulated by DUSP5. by Raman G. Kutty (3390200)

“…Plots are means with error bars ±SEM. Comparisons were made using a two-tailed t-test, *: p<0.05, **: p<0.01 ***: p<0.005.…”

Differences in lipid mediators between sPTB and FTB in obese and underweight groups. by Kamil Borkowski (629694)

“…Saturated and monounsaturated fatty acids were not measured in this assay and are indicated only to visualize parent fatty acids for measured oxylipins and endocannabinoids. Means of individual metabolites and corresponding p-values are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0239115#pone.0239115.s003" target="_blank">S2 Table</a>.…”

Cardiolipin is required to maintain protein import upon mtUPR. by Daniel Poveda-Huertes (4609723)

“…(D) Quantification of imports from (A)-(C). Compared is the longest import time point from <i>crd1Δmas1</i>^<i>ts</i> in comparison to <i>crd1Δ</i>. n = 3, data represent means ± SEM. …”

Assessment of B cell development in the BM of transgenic mice. by Ying Xing (278605)

“…<p>BM cells from the indicated mouse strains were stained with anti-B220, anti-CD43, and anti-IgM, and were analyzed by FACS. (A) The gates in panels represent Hardy fractions A-D (proB to preBII), and can be divided into fraction A-C (proB to preBI, upper rectangle) and fraction D (preBII, lower rectangle) by the expression of CD43. …”

Data Base COVID proyect by Carolina Cubillos Zapata (15345850)

“…<p> COVID-19 has emerged as a devastating disease in the last 2 years. Many authors appointed to the importance of kallikrein-kinin system (KKS) in COVID-19 pathophysiology as it is involved in inflammation, vascular homeostasis, and coagulation. …”

Influence of NOD on TNF-α mediated NFκB activation. by Maximilia C. Hottenrott (452847)

“…Note that in the condition of TNF-α+NOD phosphorylation of p65 at Ser276 is not detectable in the nuclear extracts and that expression of total p65 in both nuclear and cytoplasmic extracts is decreased. The results of a representative experiment are shown. …”

Supplementary Material for: Nasonia Parasitic Wasps Escape from Haller's Rule by Diphasic, Partially Isometric Brain-Body Size Scaling and Selective Neuropil Adaptations by Groothuis J. (4531123)

“…Haller's rule states that brains scale allometrically with body size in all animals, meaning that relative brain size increases with decreasing body size. …”