Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…We confirmed experimentally that the interaction is predominantly driven by electrostatic forces, and using noncanonical amino acids as photo-cross-linkers, we identified 16 residues in ASIC1a contributing to Big Dyn binding. Covalently tethering Big Dyn to its ASIC1a binding site dramatically decreased the proton sensitivity of channel activation, suggesting that Big Dyn stabilizes a resting conformation of ASIC1a and dissociates from its binding site during channel opening.…”

GluN2A(D731N) decreases current amplitudes and shortens synaptic-like response time course. by Kai Gao (120150)

Subjects:

Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain. by Vanessa Khemici (814639)

“…<p><b>(A)</b><i>fapR</i> mRNA levels decrease in ACC and biotin related suppressor strains. …”

Optimal allocation of clusters and efficiency of uniform allocation in a cohort design. by Mirjam Moerbeek (8603520)

JNK inhibitor AS601245 decreased levels of Bim and CC3 proteins and reduced neuronal apoptosis and brain infarct volume in P7 rat after HI. by Deyuan Li (769599)

“…The infarct volume in the AS601245-treated brain was decreased by 58% compared with the DMSO controls (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132998#pone.0132998.g004" target="_blank">Fig 4I</a>).…”

Assays of TUNEL revealed a decreased number of apoptotic cell after oroxylin A treatment. by Shu-Fang Lin (4167091)

Shift toward greater pathologic post-myocardial infarction remodeling with loss of the adaptive hypertrophic signaling of alpha1 adrenergic receptors in mice by Che-Chung Yeh (4615582)

“…</p><p>Results</p><p>Alpha1A-AR knockout paradoxically increased post-MI hypertrophy compared to wild type controls (WT), but also increased ventricular dilatation, fibrosis, apoptosis, and 4-week post-MI mortality (64% in AKO vs. 25% in WT, P = 0.02), suggesting a shift toward greater pathologic hypertrophy in the absence of pro-adaptive alpha1A effects. alpha1A-AR knockout increased phospho-p38 levels in the pre-MI myocardium compared to WT (0.55 ± 0.16 vs. 0.03 ± 0.01, P<0.05) but decreased phospho-ERK1/2 post-MI (0.49 ± 0.35 arbitrary units vs. 1.55 ± 0.43 in WT, P<0.05). …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

(a) Dependence of δ on η with κ = 2.0 by Shu-Wei Song (557396)

“…As the spin–orbit coupling strength gets larger and larger, the spatial displacement decreases at a rate inversely proportional to the spin–orbit coupling strength. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…Maternal peripheral leukocytes can be used to monitor a variety of physiological processes occurring in the body. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…Maternal peripheral leukocytes can be used to monitor a variety of physiological processes occurring in the body. …”

Variables of trees located at coordinates . by Alexandra M. Campbell (3284094)

“…Furthermore, uncertainty analysis showed that the mean MSI of the population decreased over a 100-year period without weevil predation, and this trend was exacerbated by the presence of weevil predation.…”

Global parameters and variables for the model. by Alexandra M. Campbell (3284094)

“…Furthermore, uncertainty analysis showed that the mean MSI of the population decreased over a 100-year period without weevil predation, and this trend was exacerbated by the presence of weevil predation.…”

Variables of patch located at coordinates . by Alexandra M. Campbell (3284094)

“…Furthermore, uncertainty analysis showed that the mean MSI of the population decreased over a 100-year period without weevil predation, and this trend was exacerbated by the presence of weevil predation.…”

MRSP Data collected in March 2018. by Alexandra M. Campbell (3284094)

“…Furthermore, uncertainty analysis showed that the mean MSI of the population decreased over a 100-year period without weevil predation, and this trend was exacerbated by the presence of weevil predation.…”

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. by Dong Ma (584680)

Subjects:

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)