Supplementary Material for: Clinical Utility of KidneyIntelX in Early Stages of Diabetic Kidney Disease in the CANVAS Trial by Lam D. (11931392)

“…<b><i>Introduction:</i></b> KidneyIntelX is a composite risk score, incorporating biomarkers and clinical variables for predicting progression of diabetic kidney disease (DKD). …”

Quantitative Real-Time Polymerase Chain Reaction Measurement of <i>HLA-DRA</i> Gene Expression in Whole Blood Is Highly Reproducible and Shows Changes That Reflect Dynamic Shifts i... by Sara Cajander (2657173)

“…<div><p>Introduction</p><p>A decrease in the expression of monocyte surface protein HLA-DR (mHLA-DR), measured by flow cytometry (FCM), has been suggested as a marker of immunosuppression and negative outcome in severe sepsis. …”

Key safety measures including adverse events. by Anuja Dokras (8679261)

“…<div><p>Background</p><p>The risk-to-benefit ratio of using combined oral contraceptive pills (COCPs) and/or metformin for comprehensive management of polycystic ovary syndrome (PCOS) in women with obesity is unclear. As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.…”

Table1_Stigma towards women requesting abortion and association with health facility staff facilitation and obstruction of abortion care in South Africa.docx by Abongile Jim (16363203)

“…A total of 279 clinical and non-clinical health facility workers were surveyed. …”

image_1.tif by Katrin Zlabinger (4498639)

“…Background<p>Intracoronary (IC) injection of mesenchymal stem cells (MSCs) results in a prompt decrease of absolute myocardial blood flow (AMF) with late and incomplete recovery of myocardial tissue perfusion. …”

image_3.tif by Katrin Zlabinger (4498639)

“…Background<p>Intracoronary (IC) injection of mesenchymal stem cells (MSCs) results in a prompt decrease of absolute myocardial blood flow (AMF) with late and incomplete recovery of myocardial tissue perfusion. …”

Image_1_CD4+CD25+CD127-Foxp3+ and CD8+CD28- Tregs in Renal Transplant Recipients: Phenotypic Patterns, Association With Immunosuppressive Drugs, and Interaction With Effector CD8+... by Mostafa G. Aly (10807318)

“…</p>Methods<p>We recruited 32 HC, 83 ESKD, 51 early Tx, 95 late Tx, and 9 transplant patients with a recent steroid-treated acute cellular rejection. …”

Drivers of global and national CO₂ emissions changes 2000–2017 by Qiwen Xia (9925077)

“…<p>Understanding the drivers of CO₂ emissions changes is useful in supporting future mitigation. This study applies a log-mean divisia index decomposition to assess four drivers of CO₂ emissions changes – population, income, energy intensity and carbon intensity – in 138 countries worldwide over the period 2000–2017. …”

DataSheet1_Anticancer potential of acetone extracts from selected Potentilla species against human colorectal cancer cells.docx by Daniel Augustynowicz (13878074)

“…Results of the MTT assay revealed that all tested extracts decreased the viability of both cell lines; however, a markedly stronger effect was observed in the colon cancer cells. …”

DataSheet1_Long-term effects of lumacaftor/ivacaftor on paranasal sinus abnormalities in children with cystic fibrosis detected with magnetic resonance imaging.docx by Lena Wucherpfennig (13153803)

“…In children starting therapy in school age the CRS-MRI sum score decreased longitudinally from MRI1 to MRI2 (−2.1 ± 3.5, p < 0.05), MRI3 (−3.0 ± 3.7, p < 0.01) and MRI4 (−3.6 ± 4.7, p < 0.01), mainly due to a decrease in the mucopyoceles subscore (−1.0 ± 1.5, p = 0.059; −1.2 ± 2.0, p < 0.05; −1.6 ± 1.8, p < 0.01; and −2.6 ± 2.8, p = 0.417, respectively). …”

Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to <i>L</i>. <i>amazonensis</i> control mediated by P2X7 receptor and leukotriene B₄ by Mariana M. Chaves (6871907)

“…<div><p>Leishmaniasis is a neglected tropical disease affecting millions of individuals worldwide. …”

UTX-1 is required for VPA action in <i>C. elegans</i> embryos and in human cells. by Rakel Brendsdal Forthun (121022)

“…Numbers shown are arbitrary units compared to negative control siRNA. The blot shows a 60% decrease in UTX by siRNA treatment, confirming the efficacy of transfection. …”

Equilibria and Structure of the Lanthanide(III)-2-hydroxy-1,3-diaminopropane-<i>N</i>,<i>N</i>,<i>N</i>‘,<i>N</i>‘-tetraacetate Complexes:  Formation of Alkoxo-Bridged Dimers in So... by Gyula Tircsó (2487286)

“…The complex formed between 1,3-diamino-2-hydroxypropane-<i>N</i>,<i>N</i>,<i>N</i>‘,<i>N</i>‘-tetraacetic acid (H₄L-OH) and Nd³⁺ at pH 7.5 was found to be a dinuclear dimer in the solid state by X-ray crystallography. …”

<i>In vitro</i> and <i>in vivo</i> antitumor activity of PEITC and Trisenox in imatinib resistant cells. by Jérome Kluza (5649763)

“…<p>(A) DA1-3b and DA1-3b/M2 cells were treated with 1, 3, 5, 10, 15 and 20 µM of the pro-oxidant phenethyl isothiocyanate (PEITC) for 18 h (left) or with 1, 5, 10 and 20 µM of arsenic trioxide (Trisenox) for 4 h then mitochondrial ROS production was assessed by flow cytometry using MitoSox. …”

Conditional disruption of the <i>P</i>. <i>falciparum RAMA</i> gene. by Emma S. Sherling (7354880)

“…(D) Diagnostic PCR showing efficient RAP-induced excision of the floxed sequence in the <i>RAMAloxP</i> parasite clones, leading in both cases to the expected decrease in amplicon size from 594 bp to 304 bp. Primer identities are colour-coded as in panel (A). …”

Characteristics of first responder cells. by Vira Kravets (11718439)

“…(<b>M</b>) Percent of the original first responders that remain among the earliest responders after adjustment of the spatial position of the first responders in 3 separate distributions (spheres) (<i>n</i> = 5 seeds). (<b>N</b>) Decrease in the AUC of the first phase of the Ca²⁺ response following de-coupling (removal) of a given % of the first responder or a random set of cells from the islet (<i>n</i> = 5 seeds). …”

FoxP is required for dendritic growth and negatively regulates branching of type IV da neurons. by Anna Castells-Nobau (478493)

“…(E-N) Quantitative analysis of dendritic trees, <i>FoxP</i>^<i>-/-</i> presents a decrease in (E) dendritic field area and (F) average branch length. …”

Image_1_Hepatitis B Vaccine Non-Responders Show Higher Frequencies of CD24highCD38high Regulatory B Cells and Lower Levels of IL-10 Expression Compared to Responders.pdf by Nina Körber (469767)

“…Anti-HBs seroconversion accompanied by a decrease of Breg numbers after booster immunization with a third-generation hepatitis B vaccine could indicate a positive effect of third-generation hepatitis B vaccines on Breg-mediated immunomodulation in hepatitis B vaccine non-responders.…”

Structural, Thermodynamic, and Mesomorphic Consequences of Replacing Nitrates with Trifluoroacetate Counteranions in Ternary Lanthanide Complexes with Hexacatenar Tridentate Ligand... by Homayoun Nozary (1314306)

“…This translates into a considerable decrease of the affinity of the <b>L</b><b><i>i</i></b>^C12 (<i>i</i> = 3, 4) ligands for Ln(CF₃CO₂)₃ in solution, thus leading to significant dissociation of the [Ln(<b>L</b><b><i>i</i></b>^C12)(CF₃CO₂)₃] complexes at millimolar concentrations. …”

Image_2_Hepatitis B Vaccine Non-Responders Show Higher Frequencies of CD24highCD38high Regulatory B Cells and Lower Levels of IL-10 Expression Compared to Responders.jpeg by Nina Körber (469767)

“…Anti-HBs seroconversion accompanied by a decrease of Breg numbers after booster immunization with a third-generation hepatitis B vaccine could indicate a positive effect of third-generation hepatitis B vaccines on Breg-mediated immunomodulation in hepatitis B vaccine non-responders.…”