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145461
Percentage change of clinical and QOL parameters throughout PEs in CF.
Published 2014“…Other QOL domains which decreased at Day 1 include: Vitality, Health Perceptions, Social and Role (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0088567#pone.0088567.s002" target="_blank">Table S1</a>). …”
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145462
Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of <i>C</i>. <i>albicans</i> Virulence Pathways
Published 2015“…The Ras1 GTPase activating protein, Ira2, but not the Ras1 guanine nucleotide exchange factor, Cdc25, was required for the reduction of Ras1-GTP in response to inhibitor-mediated reduction of ATP levels. Furthermore, Cyr1, a well-characterized Ras1 effector, participated in the control of Ras1-GTP binding in response to decreased mitochondrial activity suggesting a revised model for Ras1 and Cyr1 signaling in which Cyr1 and Ras1 influence each other and, together with Ira2, seem to form a master-regulatory complex necessary to integrate different environmental and intracellular signals, including metabolic status, to decide the fate of cellular morphology.…”
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145463
Image_4_Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antit...
Published 2018“…Finally, hyperglycemia reduced cell death by decreasing the cell percentage in sub-G1 peak induced by DOX (via a cell cycle arrest in the G2/M phase) and 5-FU (via a cell cycle arrest in the S phase) in HT29 and LOVO cells. …”
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145464
Image_2_Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antit...
Published 2018“…Finally, hyperglycemia reduced cell death by decreasing the cell percentage in sub-G1 peak induced by DOX (via a cell cycle arrest in the G2/M phase) and 5-FU (via a cell cycle arrest in the S phase) in HT29 and LOVO cells. …”
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145465
Data_Sheet_1_Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to...
Published 2018“…Finally, hyperglycemia reduced cell death by decreasing the cell percentage in sub-G1 peak induced by DOX (via a cell cycle arrest in the G2/M phase) and 5-FU (via a cell cycle arrest in the S phase) in HT29 and LOVO cells. …”
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145466
PA affects response strength and duration but not cortical bursting properties.
Published 2013“…The magnitudes of PBI were a function of sound intensity and proportional to response amplitude; inhibition was the strongest when it followed high-intensity stimulation, decreasing monotonically with decreasing intensity. …”
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145467
Effect of different subclasses of hugin neurons on the motor pattern underlying feeding and locomotion behavior.
Published 2014“…Activation of dTrpA1 in Hug0.8-Gal4 significantly decreased the cycle frequency of the AN-motor pattern, but not in HugVNC-Gal4 (colored bars indicate the motor pattern). …”
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145468
Effect of different subclasses of hugin neurons on the motor pattern underlying feeding and locomotion behavior.
Published 2014“…Activation of dTrpA1 in Hug0.8-Gal4 significantly decreased the cycle frequency of the AN-motor pattern, but not in HugVNC-Gal4 (colored bars indicate the motor pattern). …”
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145469
Lifetime images of infected red blood cells.
Published 2008“…Arrows in panel C and E indicate the appearance of a bright edge in the IRBCs. The correspondent fluorescence lifetime images (<i>B</i>, <i>D and F</i>) reveal a significant increase in fluorescent lifetime in the host cytosol of infected cells relative to that in uninfected RBCs reflecting a decreased hemoglobin concentration.…”
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145470
Diversity of mutational paths in the primary/promiscuous activity space.
Published 2012“…Mutational steps are allowed if the primary activity is decreased and the promiscuous activity is maintained above a given threshold (shown as a horizontal black line).…”
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145471
The influence of bulkiness of the amino acid residue on the liquid crystalline behaviours of some fluorinated compounds
Published 2021“…<p>A series of fluorinated compounds with an amino acid residue are synthesized, which show smectic phases. …”
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145472
The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity
Published 2012“…In addition, decreased TRAP1 expression in [A53T]α-Synuclein–expressing flies resulted in enhanced loss of climbing ability and sensitivity to oxidative stress. …”
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145473
Exposure to household pet cats and dogs in childhood and risk of subsequent diagnosis of schizophrenia or bipolar disorder
Published 2019“…</p><p>Results</p><p>We found that exposure to a household pet dog was associated with a significantly decreased hazard of having a subsequent diagnosis of schizophrenia (Hazard Ratio .75, p < .002) Furthermore, a significant decreased relative risk of schizophrenia was detected following exposure at birth and during the first years of life. …”
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145474
Dopamine Inhibits Mitochondrial Motility in Hippocampal Neurons
Published 2008“…<div><h3>Background</h3><p>The trafficking of mitochondria within neurons is a highly regulated process. In an earlier study, we found that serotonin (5-HT), acting through the 5-HT1A receptor subtype, promotes axonal transport of mitochondria in cultured hippocampal neurons by increasing Akt activity, and consequently decreasing glycogen synthase kinase (GSK3β) activity. …”
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145475
Automated, high-throughput phenotyping.
Published 2022“…<p>a. A coarse classification scheme for behavioral aging and death involving four states. b. …”
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145476
Summary of observed scenarios / variants of changing Impact Factor (IF).
Published 2016“…<p>(A) IF increases (left bars) and decreases (right bars) for each annual step 2010–11 to 2013–14. …”
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145477
Safety pin arrangements 2
Published 2018“…Moreover, they can show a broader range of qualitatively different orderings, even with similar levels of order: C and D are both quite ordered but in very different ways (grouped by size in decreasing order in C and in order of increasing versus decreasing size in D).…”
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145478
MARGO tracking throughput.
Published 2019“…The acquisition rate decreased exponentially, consistent with a linear increase in inter-frame interval as a function of ROI number.…”
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145479
S-plots for gene selection of three classes with subtypes.
Published 2013“…From this S-plot, five genes with elevated and reduced levels in ALL-B, respectively, were selected. C, A typical gene (M27891_at) with a profile of increased expression levels in AML and decreased levels in ALL-T and ALL-B. …”
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145480
Devaluation of fructose 1.66 M.
Published 2013“…(<b>b</b>) Ingestion of quinine, LiCl and amygdaline decreased US responsiveness with respect to a water control. …”