Image_2_Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia.tiff by Gabrielle M. Siegers (123297)

“…Mechanistically, we determined that natural killer group 2, member D (NKG2D) on γδTc and the NKG2D ligand MHC class I polypeptide-related sequence A (MICA)/B on MCF-7 and T47D breast cancer cell lines are important for γδTc cytotoxicity, but that MIP1α, RANTES, and CD40L do not play a direct role in cytotoxicity. …”

Image_4_Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia.tiff by Gabrielle M. Siegers (123297)

“…Mechanistically, we determined that natural killer group 2, member D (NKG2D) on γδTc and the NKG2D ligand MHC class I polypeptide-related sequence A (MICA)/B on MCF-7 and T47D breast cancer cell lines are important for γδTc cytotoxicity, but that MIP1α, RANTES, and CD40L do not play a direct role in cytotoxicity. …”

Table_4_miR-181a-5p Regulates TNF-α and miR-21a-5p Influences Gualynate-Binding Protein 5 and IL-10 Expression in Macrophages Affecting Host Control of Brucella abortus Infection.P... by Patrícia P. Corsetti (459690)

“…Taken together, the results indicate that downregulation of mmu-miR-21a-5p induced by infection increases GBP5 levels and decreases IL-10 expression thus contributing to bacterial control in host cells.…”

Data_Sheet_2_Co-infection of Cytomegalovirus and Epstein-Barr Virus Diminishes the Frequency of CD56dimNKG2A+KIR− NK Cells and Contributes to Suboptimal Control of EBV in Immunosup... by Janice K. P. Lam (4916524)

“…PTLD patients had markedly decreased frequency of CD56^dimNKG2A⁺Killer Immunoglobulin-like receptor (KIR)⁻ NK cells from the time of diagnosis through remission compared to those of IM patients. …”

Data_Sheet_1_Co-infection of Cytomegalovirus and Epstein-Barr Virus Diminishes the Frequency of CD56dimNKG2A+KIR− NK Cells and Contributes to Suboptimal Control of EBV in Immunosup... by Janice K. P. Lam (4916524)

“…PTLD patients had markedly decreased frequency of CD56^dimNKG2A⁺Killer Immunoglobulin-like receptor (KIR)⁻ NK cells from the time of diagnosis through remission compared to those of IM patients. …”

Table_1_Lasting increases in trait mindfulness after psilocybin correlate positively with the mystical-type experience in healthy individuals.DOCX by Anna Søndergaard (13910640)

“…Recent studies indicate that trait mindfulness is increased 3 months after psilocybin intake, preceded by decreases in neocortical serotonin 2A receptor (5-HT_2AR) binding. …”

Table_6_miR-181a-5p Regulates TNF-α and miR-21a-5p Influences Gualynate-Binding Protein 5 and IL-10 Expression in Macrophages Affecting Host Control of Brucella abortus Infection.P... by Patrícia P. Corsetti (459690)

“…Taken together, the results indicate that downregulation of mmu-miR-21a-5p induced by infection increases GBP5 levels and decreases IL-10 expression thus contributing to bacterial control in host cells.…”

Synthesis and Characterization of a New Family of Mixed Oxide−Proton Conductors Based on Tristrontium Oxysilicate by José M. Porras-Vázquez (2450377)

“…A large p-type electronic contribution was also observed for Sr₃(Si_0.89Al_0.11O₄)O_0.945◻_0.055 under oxidizing conditions, decreasing the oxide ion transference number to ∼0.01 at 1173 K.…”

Synthesis and Characterization of a New Family of Mixed Oxide−Proton Conductors Based on Tristrontium Oxysilicate by José M. Porras-Vázquez (2450377)

“…A large p-type electronic contribution was also observed for Sr₃(Si_0.89Al_0.11O₄)O_0.945◻_0.055 under oxidizing conditions, decreasing the oxide ion transference number to ∼0.01 at 1173 K.…”

Image_1_Prenatal Cadmium Exposure Alters Proliferation in Mouse CD4+ T Cells via LncRNA Snhg7.pdf by Jamie L. McCall (6194741)

“…The induction of lncSnhg7 is enhanced in splenic T cells from Cd offspring resulting in the upregulation of GALNT7 protein and increased proliferation following activation. miR-34a overexpression decreased GALNT7 expression and knockdown of lncSnhg7 inhibited proliferation suggesting that the lncSnhg7/miR-34a/GALNT7 is an important pathway in primary CD4⁺ T cells. …”

Natural disease history of the <i>dy^2J</i> mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy by S. Pasteuning-Vuhman (4348486)

“…<div><p>Merosin deficient congenital muscular dystrophy 1A (MDC1A) is a very rare autosomal recessive disorder caused by mutations in the <i>LAMA2</i> gene leading to severe and progressive muscle weakness and atrophy. …”

Image_2_Cytotoxicity of Donor Natural Killer Cells to Allo-Reactive T Cells Are Related With Acute Graft-vs.-Host-Disease Following Allogeneic Stem Cell Transplantation.TIF by Lixia Sheng (8285694)

“…Using univariate analysis, higher NK degranulation activities in allografts (CD107a^high) were correlated with a decreased risk in grade I–IV aGVHD (hazard risk [HR] = 0.294; P < 0.0001), grade III–IV aGVHD (HR = 0.102; P < 0.0001), and relapse (HR = 0.157; P = 0.015), and improved overall survival (HR = 0.355; P = 0.028) after allo-HSCT. …”

Image_1_Functional molecular expression of nature killer cells correlated to HBsAg clearance in HBeAg-positive chronic hepatitis B patients during PEG-IFN α-2a therapy.tif by Weihua Cao (504059)

“…Objective<p>To explore whether the frequencies and functional molecules expression of Natural Killer cells (NK cells) are related to hepatitis B surface antigen (HBsAg) disappearance in hepatitis B e envelope antigen (HBeAg)-positive patients with chronic hepatitis B (CHB) throughout peginterferon alpha-2a (PEG-IFN α-2a) treatment.</p>Methods<p>In this prospective research, HBeAg-positive patients with CHB received PEG-IFN α-2a treatment, completing 4-year follow-up. …”

Image_1_Cytotoxicity of Donor Natural Killer Cells to Allo-Reactive T Cells Are Related With Acute Graft-vs.-Host-Disease Following Allogeneic Stem Cell Transplantation.TIF by Lixia Sheng (8285694)

“…Using univariate analysis, higher NK degranulation activities in allografts (CD107a^high) were correlated with a decreased risk in grade I–IV aGVHD (hazard risk [HR] = 0.294; P < 0.0001), grade III–IV aGVHD (HR = 0.102; P < 0.0001), and relapse (HR = 0.157; P = 0.015), and improved overall survival (HR = 0.355; P = 0.028) after allo-HSCT. …”

Diagnostic value and relative weight of sequence-specific magnetic resonance features in characterizing clinically significant prostate cancers by Olivier Rouvière (3608000)

“…</p><p>When moving from csPCa-A to csPCa-B and csPCa-C definitions, the added value of V_Max, dPSA and ECE increased as compared to signal-related variables, and the added value of DCE decreased.…”

Synthesis and Structural Studies of Platinum Complexes Containing Monodentate, Bridging, and Chelating Formamidine Ligands by F. Albert Cotton (1781341)

“…On going from the bis-bridged, bis-chelate structure in <b>2a</b> to the tetrabridged structure in <b>3a</b>, the metal−metal separation decreases from 2.910(1) to 2.649(1) Å. …”

Image_3_Cytotoxicity of Donor Natural Killer Cells to Allo-Reactive T Cells Are Related With Acute Graft-vs.-Host-Disease Following Allogeneic Stem Cell Transplantation.TIF by Lixia Sheng (8285694)

“…Using univariate analysis, higher NK degranulation activities in allografts (CD107a^high) were correlated with a decreased risk in grade I–IV aGVHD (hazard risk [HR] = 0.294; P < 0.0001), grade III–IV aGVHD (HR = 0.102; P < 0.0001), and relapse (HR = 0.157; P = 0.015), and improved overall survival (HR = 0.355; P = 0.028) after allo-HSCT. …”

Impact of Aromatic Ring Count on the Ability to Participate in Attractive Interactions. Crystal Structure (X-ray) and Solid State Computational (DFT/QTAIM/RDS/Hirshfeld-surfaces) S... by Jolanta Natalia Latosińska (2122843)

“…The crystal structure of 1,4-di­(2-phenyl-1<i>H</i>-imidazol-4-yl)­benzene (DPI4B) is determined by X-ray diffraction with a final <i>R</i>-factor of 6.42% at room temperature. …”

Acid-Promoted sp³ C–H Bond Cleavage in a Series of (2-Allylphenoxo)ruthenium(II) Complexes. Mechanistic Insight into the Aryloxo–Acid Interaction and Bond Cleavage React... by Masafumi Hirano (1409539)

“…The association constant <i>K</i>₂ (<i>K</i>₂ = [<b>2</b>·HOR]/([<b>2</b>]­[HOR])) increases on decreasing the p<i>K</i>_a value of the acid employed and on increasing the induction effect of substituents at the 4-position in the aryloxo group. …”

DataSheet_1_Short-chain fatty acids induced lung tumor cell death and increased peripheral blood CD4+ T cells in NSCLC and control patients ex vivo.pdf by Carolin D. Thome (18325080)

“…SB treatment resulted in a decreased production of IFN-γ and granzyme B in CD8+ T cells and NK cells. …”