Phosphoethanolamine Modification of <i>Neisseria gonorrhoeae</i> Lipid A Reduces Autophagy Flux in Macrophages by Susu M. Zughaier (239014)

“…Phosphoethanolamine (PEA) addition to the 4' position of the lipid A (PEA-lipid A) moiety of the lipooligosaccharide (LOS) produced by gonococci performs a critical role in this pathogen’s ability to evade innate defenses by conferring decreased susceptibility to cationic antimicrobial (or host-defense) peptides, complement-mediated killing by human serum and intraleukocytic killing by human neutrophils compared to strains lacking this PEA decoration. …”

DataSheet_1_PRDX6: A protein bridging S-palmitoylation and diabetic neuropathy.pdf by Yan Cao (482880)

“…S-palmitoylation is a reversible posttranslational lipid modification, and its dysregulation has been implicated in metabolic syndrome, cancers, neurological disorders, and infections. …”

Thromboembolism adverse event profiles of thrombopoietin receptor agonists: a real-world, pharmacovigilance study by Xintian Xu (10891575)

Image_1_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Expression of a Constitutively Active Calcineurin Encoded by an Intron-Retaining mRNA in Follicular Keratinocytes by Atsushi Fujimura (227683)

“…Overexpression of cyclin G2 arrested the cell cycle in follicular keratinocytes <em>in vitro</em> and the Cn inhibitor, cyclosporin A, inhibited nuclear localization of NFATc2, resulting in decreased cyclin G2 expression in follicular keratinocytes of rats <em>in vivo</em>. …”

Table_7_Effects of Taurine on Primary Metabolism and Transcription in a Coral Symbiodinium sp..xlsx by Aiyou Huang (404014)

“…The results revealed that taurine significantly increased the growth, photosynthesis efficiency, total soluble sugar, chlorophyll a, and chlorophyll b and free amino acid content of Symbiodinium sp. while decreased the content of total insoluble sugar. …”

Table_3_A Role for PICKLE in the Regulation of Cold and Salt Stress Tolerance in Arabidopsis.xlsx by Rong Yang (107028)

“…<p>Arabidopsis PICKLE (PKL) is a putative CHD3-type chromatin remodeling factor with important roles in regulating plant growth and development as well as RNA-directed DNA methylation (RdDM). …”

Image_5_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Image_2_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.PDF by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Supplementary Material for: Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism by Vajravelu M.E. (5607443)

“…<b><i>Methods:</i></b> This was a retrospective cohort of infants with HI treated with IGD from 2009–2017. …”

Human Neutrophil Peptide-1 (HNP-1): A New Anti-Leishmanial Drug Candidate by Sara Dabirian (473544)

“…There is a considerable increase in TNF-α production from rHNP-1-treated neutrophils and decreased level of TGF-β concentration, a response that should potentiate the immune system against parasite invasion. …”

IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models by Anjelika Gasilina (8566296)

“…<div><p>We report the synthesis and preliminary characterization of IODVA1, a potent small molecule that is active in xenograft mouse models of Ras-driven lung and breast cancers. …”

Use of Thiopurines and Risk of Colorectal Neoplasia in Patients with Inflammatory Bowel Diseases: A Meta-Analysis by Jianfeng Gong (177593)

“…The use of thiopurines was associated with a statistically significant decreased incidence of colorectal neoplasm (summary RR=0.71, 95% CI=0.54–0.94, p=0.017), even after adjustment for duration and extent of the disease, but there was high heterogeneity among studies (<i>I</i>²=68.0%, p<0.001). …”

Clinical value of thalidomide on kk-rat model through TNF-a mediated inflammation approach by Min HUANG (12728997)

“…The levels of TNF-α, IL-1β, interleukin -6 (IL-6) and interleukin -18 (IL-18) of kk-Ay in the thalidomide group and the model control group were both at a higher level before treatment, but the difference was not statistically significant (P >0.05); The levels of TNF-α, IL-1β, interleukin -6 (IL-6) and interleukin -18 (IL-18) in kk-Ay rats 8/10/12 weeks after the treatment in the thalidomide group were significantly decreased, with statistically significant differences compared with the model control group (P < 0.05). …”

StarCraftImage: A Dataset For Prototyping Spatial Reasoning Methods For Multi-Agent Environments by Sean Kulinski (12881885)

“…StarCraft II game replays encode intelligent (and adversarial) multi-agent behavior and could provide a testbed for these tasks; however, extracting simple and standardized representations for prototyping these tasks is laborious and hinders reproducibility. …”

Table_2_Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.DOCX by Sebastian Reichert (553783)

“…<p>In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. …”

Supplementary Material for: Long-Term Outcomes of Developmental Exposure to Fluoxetine: A Review of the Animal Literature by Kiryanova V. (4142347)

“…An estimated 1.4-2.1% of pregnant women use this medication, which inhibits the reuptake of serotonin and thereby increases serotonergic activity at the synapse. Serotonin acts as a cue guiding numerous neurodevelopmental processes, and changes in the concentration of serotonin can disrupt normal in utero brain development and organization in humans and other animals, thus providing a mechanism by which maternal intake of FLX might alter neural development and ultimately behaviour. …”

Establishment of a yeast essential protein conditional-degradation library and screening for autophagy-regulating genes by Yi Zhang (9093)

“…In summary, the yeast essential protein conditional degradation library we constructed will serve as a valuable resource for systematically investigating the roles of essential genes in autophagy and other biological functions.…”

<i>NEXN</i> Is a Novel Susceptibility Gene for Coronary Artery Disease in Han Chinese by Chong Wu (130393)

“…Further eQTL analysis demonstrated that the risk allele T of rs1780050 is associated with decreased expression of NEXN, thus contributing to a higher risk of CAD susceptibility in the population. …”

Mesomorphic properties of cyanobiphenyl dimers with a substituted central malonate unit: overruling effect of fluorination by Marco André Grunwald (5425064)

“…In case of C2-hexyl-substituted dimers, shorter spacers favoured N phases (n = 6–9), while longer spacers favoured SmA phases (n ≥ 9). In addition, decreased clearing temperatures were observed. …”