Effect of specific inhibitors on CYP-mediated CK (50 μM) metabolism in HLMs. by Jian Xiao (253329)

“…<p>Note: Furafylline, tranylcypromine, sulfaphenazole, quinidine, chlormethiazole, ticlopidine, and ketoconazole were used as the specific inhibitors for CYP1A2, CYP2A6, CYP2C9, CYP2D6, CYP2E1, and CYP2C19, respectively. …”

Thermal Conductivity of a 2D Covalent Organic Framework and Its Enhancement Using Fullerene 3D Self-Assembly: a Molecular Dynamics Simulation by Daili Feng (8659245)

“…Furthermore, a newly reported nanopatterning C60@COF-1 composite material is predicted to have a huge boost in thermal conductivity with an order of magnitude of 10 W/(m·K). …”

Enhancer functions of ICR1 and ICR2. by Salvatore Costa (633617)

“…Structure and conventions are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170969#pone.0170969.g001" target="_blank">Fig 1</a>, except that the arrowed yellow box represents the Luc reporter gene. …”

NO measurement after BPP-BrachyNH₂ addition on endothelium-intact rat aorta cross sections assessed by using a confocal scanning laser microscope. by Daniel Dias Rufino Arcanjo (536744)

Comparison of cilostazol- and resveratrol-stimulated P-LKB1 and P-AMPKα expressions in N2a cells that LKB1 is detectable, and in HeLa cells that lack LKB1. by So Youn Park (141327)

“…Proposed signal pathways for the neuroprotective effect of cilostazol against Aβ-induced neurotoxicity: Cilostazol upregulates autophagy through activating SIRT1/LKB1/AMPK1α signal pathways and depletes intracellular Aβ and APP-CTFβ accumulation, and thereby results in decreased neurotoxicity.…”

Summary maps of hedonic and aversive shifts produced by GABA-A agonism and AMPA antagonism. by Alexis Faure (247166)

“…Criteria for including a site as hedonic was an increase >10 in ‘liking’ reactions and a decrease or no change in ‘disliking’ reactions. …”

The impact of the military mission in Afghanistan on mental health in the Canadian Armed Forces: a summary of research findings by Mark A. Zamorski (5146130)

“…Many deployed personnel will seek care, but further efforts to decrease the delay are needed. Only a fraction of the overall burden of mental illness is likely deployment attributable. …”

Myeloid lineage is affected by csrnp1a knockdown. by Jaime Espina (106906)

“…The <i>spi1</i> changes are accompanied by a significant decrease in proliferation (showed as the number of H3P within the <i>spi1</i> signal area) (E, F, and G). …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

The inactivation of the acetyl-CoA acyltransferase 1 enzyme by the novel putative miRNA Oeu124369 leads to a decrease in Acetyl-CoA production and additionally, the deactivation of palmitoyl-protein thioesterase by the same miRNA results in a reduction in palmitic acid biosynthesis in the fatty acid elongation pathway. by Mohammad Hossein Pakdel (19837942)

“…<p>The inactivation of the acetyl-CoA acyltransferase 1 enzyme by the novel putative miRNA Oeu124369 leads to a decrease in Acetyl-CoA production and additionally, the deactivation of palmitoyl-protein thioesterase by the same miRNA results in a reduction in palmitic acid biosynthesis in the fatty acid elongation pathway.…”

Housing conditions specifically impaired long-term SRM (mean±SEM): A) Rats in group housing displayed a significant decrease in SIT during the second 5 min encounter (A2, empty bars) compared to the first (A1, gray bars), regardless of the time interval between the encounters. by Hadar Shahar-Gold (283031)

“…B) Socially isolated rats displayed a significant decrease in SIT measured during the second encounter only for intervals of 30 and 60 min but not for a 120 min interval. …”

Notch signaling regulates fused mitochondrial morphology in INPs and muscle cells. by Dnyanesh Dubal (12085942)

A raincloud plot of the cuteness ratings. by Amanda C. Hahn (17241106)

Correlation of urinary CXCL1 level with proteinuria during follow-up period. by Yanfeng Zhao (308108)

“…<p>For patients with high baseline urinary CXCL1 levels (case 1 & case 2), the variation tendencies of urinary CXCL1 and proteinuria were almost the same (A & B). For patients with middle levels of baseline urinary CXCL1 (case 3 & case 4), although proteinuria relieved a lot, urinary CXCL1 levels just decreased a little (C & D). …”

The effect on plasma membrane expression of AMPA receptor subunits in hippocampal culture after presynaptic silencing with Bafilomycin (BAF). by Suleman Hussain (816864)

“…There is a slight, but significant decrease in labeling intensities after Bafilomycin treatment. …”

Metformin inhibits glutaminase activity in a dose dependent manner: from 17.5% at 10 mM up to 68% at 100 mM (A) (* p<0.05). by M. Mar Díaz-Herrero (646639)

“…<p>This effect, analyzed by Dixon plot, showed competitive inhibition kinetics, with a K_i of 14.28 mM (B). In Caco2 cells, metformin 20 mM showed 24% inhibition of glutaminase activity at 72 hours compared to control cultures (p<0.05) (glutamate production was decreased from 26.85±0.74 µM to 19.9±2.05 µM; p<0.05) (C).…”