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greater decrease » greater increase (Expand Search), greater increases (Expand Search), rate decreased (Expand Search)
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8781
Supplementary Material for: The Designer Antimicrobial Peptide A-hBD-2 Facilitates Skin Wound Healing by Stimulating Keratinocyte Migration and Proliferation
Published 2018“…<b><i>Conclusion:</i></b> Our data suggest that A-hBD-2 may be a promising candidate therapy for wound healing.…”
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8782
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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8783
A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in <em>Leishmania donovani</em>
Published 2012“…<div><p>Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (<em>N</em><sup>€</sup>-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, <em>Leishmania donovani,</em> which causes visceral leishmaniasis. …”
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8784
Efmoroctocog Alfa: A Review in Haemophilia A
Published 2021“…</p> <p><b> </b></p> <p><b>Authorship and Conflict of interest</b> James E. Frampton is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. …”
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8785
Chemoresistance of Human Monocyte-Derived Dendritic Cells Is Regulated by IL-17A
Published 2013“…Immature dendritic cells were CD40<sup>low</sup>HLADR<sup>low</sup> CD1a<sup>+</sup> MCL1<sup>+</sup>, did not express CD14, CD68 or BCL2A1, and displayed a short 2-day lifespan. …”
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8786
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8787
Porcine Coro1A inhibit <i>H.parasuis</i> induced NF-κB activation.
Published 2014“…<p>(A) PK-15 cells were transfected with pNF-κB-luc (0.2 µg) and pRL-TK (0.05 µg), then cells were control-inoculated, live or heat-killed <i>H.parasuis</i> (10<sup>7</sup> CFU) inoculated. …”
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8788
Spectral-domain optical coherence tomography (SD-OCT) images taken from a 72-year-old female patient with neovascular age-related macular degeneration (nAMD) who received ranibizum...
Published 2025“…OCT image taken at baseline (A) reveals macular neovascularization (MNV), subretinal hyperreflective material (SHRM) and subretinal fluid (SRF). …”
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8789
Reduction of NF-κB activation when porcine Coro1A was overexpressed.
Published 2014“…<p>(A) PK-15 cells were co-transfected with the pNF-κB-luc reporter plasmid (0.2 µg), pRL-TK plasmid (0.05 µg), along with 0.6 µg of the expression plasmid encoding porcine Coro1A protein. …”
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8790
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8791
HilD-activation results in a growth defect.
Published 2023“…Representative images are shown in the right panel. the same strains as in (A) were analysed. (C) Time-lapse microscopy analysis reveals a decreased cell elongation rate (left), a decrease in the maximal cell length (middle) as well as decreased length elongation during a division cycle (right) upon HilD induction. …”
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8792
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8793
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8794
Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 4
Published 2017“…</b> Treatment with 100nM triptolide decreased the mRNA expression of Sp1, HSF1 and HSP70 in MKN28 and MKN45 gastric adenocarcinoma cells in a time (24–48 hours) dependent manner. …”
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8795
Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 1
Published 2017“…</b> Treatment of moderately differentiated gastric adenocarcinoma cell line, MKN28 with triptolide decreases viability in a dose (25–100nM) as well as time (24–72 hours) dependent manner. …”
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8796
AoA results.
Published 2023“…Speech samples produced by 12 pwAD and 12 controls for the Carolinas Conversations Collection were analysed for noun, verb and pronoun counts and ratios, lexical diversity overall and among nouns and verbs, copula use, and frequencies and ages of acquisition (AoA) of nouns and verbs produced. pwAD used fewer nouns and a narrower range of words than controls, exhibiting signs of increased reliance on pronouns and decreased noun diversity. …”
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8797
Data_Sheet_1_A Tool for Computation of Changes in Na+, K+, Cl− Channels and Transporters Due to Apoptosis by Data on Cell Ion and Water Content Alteration.ZIP
Published 2019“…New experimental data for staurosporine-induced apoptosis of human lymphoma cells U937 have been obtained: the time course of changes in cellular K<sup>+</sup>, Na<sup>+</sup>, Cl<sup>−</sup>, and water content, as well as Rb<sup>+</sup> fluxes as a marker of the Na/K pump activity. Using a newly developed computational tool, we found that alteration of ion and water balance was associated with a 55% decrease in the Na<sup>+</sup>/K<sup>+</sup>-ATPase rate coefficient over a 4-h period, with a time-dependent increase in potassium channel permeability, and a decrease in sodium channel permeability. …”
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