Image 5_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Image 9_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Data Sheet 1_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.pdf by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Image 2_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Table 1_The impact of IL-17A inhibitors on scalp and gut microbiota in psoriasis.docx by Wenxia Huang (12290795)

“…<p>Objective To investigate the differences in scalp and gut microbial diversity, community structure, and specific microbial species in patients with psoriasis vulgaris before and after treatment with interleukin (IL)-17A inhibitors, compared to healthy individuals. …”

Identification of the DNA sequence within the mouse inhibin-α promoter required for Wt1A-dependent transcriptional activation. by Shao-Yang Ji (289371)

“…<p>A, TM4 cells were transiently transfected with luciferase reporter constructs bearing different lengths of the mouse Inhibin alpha promoter sequence, and Renilla luciferase reporter plasmids together with an empty plasmid (pCMV-tag2b) or Wt1A expression vector. …”

Image 13_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

SS induces breast cancer cell apoptosis, G2/M checkpoint arrest, ROS accumulation and LDH-A inhibition. by Zhiyu Wang (282312)

“…<p>(A) Annexin-Cy5 staining results showed that SS induced both breast cancer cells apoptosis in a dose-dependent manner; (B) JC-1 staining assay indicated that mitochondrial membrane potential was decreased after SS treatment, indicating that the mitochondrial pathway apoptosis was triggered by SS; (C) Cell cycle analysis showed that after SS treatment, the G2/M checkpoint was arrested in both breast cancer cell lines, presenting as a significant increase in G2/M subpopulations; (D) Hydroethidine was applied to detect the intracellular O₂⁻ level after SS administration by flow cytometry. …”

Image 2_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.jpeg by Yingying Zhang (42910)

“…Inflammatory responses were evaluated through histopathology, immunohistochemistry (NF-κB p65), and qRT-PCR analysis of cytokine expression.</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …”

Image 1_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Image 1_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.jpeg by Yingying Zhang (42910)

“…Inflammatory responses were evaluated through histopathology, immunohistochemistry (NF-κB p65), and qRT-PCR analysis of cytokine expression.</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …”

<b>Collapsin response mediator protein 2 modulates synaptic function by stabilizing the surface expression of phosphorylated AMPA receptor GluA2 subunits</b> by ren (21408623)

“…Upon phorbol myristate acetate (TPA) induced activation of protein kinase C (PKC), the surface expression of GluA2 decreased significantly, as phosphorylation of GluA2 at the S880 site is known to promote its internalization. …”

Table 1_Prevalence of azithromycin resistance after the COVID-19 era in clinical bacterial isolates from a tertiary care hospital in Gurugram, India.docx by Parbati Debnath (21189071)

“…<p>The increasing prevalence of antibiotic resistance in pathogenic bacteria poses a great healthcare problem worldwide. Azithromycin (AZM) is a very effective macrolide antibiotic to treat many bacterial infections, but increasing azithromycin resistance in clinical bacteria decreases the effectiveness of this vital antibiotic, which is a major concern. …”

Supplementary Material for: Perinatal High-Fat Diet and Bisphenol A: Effects on Behavior and Gene Expression in the Medial Prefrontal Cortex by Wise L.M. (6110090)

“…Both high-fat diets (HFD) and bisphenol A (BPA), an environmental endocrine disruptor, are prevalent in industrialized societies. …”

WNT10A Plays an Oncogenic Role in Renal Cell Carcinoma by Activating WNT/β-catenin Pathway by Ren-Jun Hsu (127121)

“…Conversely, WNT10A siRNA knockdown decreased cell proliferation and aggressiveness of RCC cells. …”

Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Table 1_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.docx by Yingying Zhang (42910)

“…Inflammatory responses were evaluated through histopathology, immunohistochemistry (NF-κB p65), and qRT-PCR analysis of cytokine expression.</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …”

Image 12_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Supplementary Material for: The Impact of <b><i>CYP24A1</i></b> Polymorphisms on Hypertension Susceptibility by Bao Q. (8272902)

“…<b><i>Results:</i></b> We found that rs56229249 of <i>CYP24A1</i>significantly<i></i>decreased the hypertension risk in homozygote (OR 0.51, 95% CI 0.29–0.91,<i> p</i> = 0.022) and recessive models (OR 0.51, 95% CI 0.29–0.91,<i> p</i> = 0.023). …”

Transwell co-culture of RAW 264.7 macrophages induces metastatic gene expression by A549 cells. by Xiuling Li (130607)

“…<b>D</b> Co-culture of RAW 264.7 macrophages decreased E-cadherin expression by A549 cells. Control A549 and A549-TPα cells were collected after 24 h of culture with or without RAW 264.7 cells as described in A. …”