<i>Trypanosoma cruzi</i> Disrupts Thymic Homeostasis by Altering Intrathymic and Systemic Stress-Related Endocrine Circuitries by Ailin Lepletier (328461)

“…These alterations were closely related with systemic changes, characterized by a stress hormone imbalance, with progressive GC augmentation simultaneously to PRL reduction. …”

The PI3K/Akt- and NO-related pathways contribute to EPC tube formation affected by oxLDL. by Feng-Yen Lin (143413)

“…<p>(A and B) EPCs were treated for 2 hours with 0–50 μg/mL oxLDL, then eNOS and Akt activation (phosphorylation) was analyzed by Western blot. …”

DataSheet_2_Disparate Interferon Signaling and Shared Aberrant Basaloid Cells in Single-Cell Profiling of Idiopathic Pulmonary Fibrosis and Systemic Sclerosis-Associated Interstiti... by Eleanor Valenzi (8508294)

“…Alveolar type I cells were dramatically decreased in both IPF and SSc-ILD, with a distinct transcriptome signature separating these cells by disease. …”

Association of Inhaled Corticosteroids with Incident Pneumonia and Mortality in COPD Patients; Systematic Review and Meta-Analysis by Emir Festic (834887)

“…<i>Conclusions:</i> Despite a substantial and significant increase in unadjusted risk of pneumonia associated with inhaled corticosteroid use, pneumonia fatality and overall mortality were found not to be increased in randomized controlled trials and were decreased in observational studies.…”

Presentation_2_Precision immunointerception of EGFR-driven tumorigenesis for lung cancer prevention.pptx by Jing Pan (95938)

“…In this study, we identified immunogenic epitopes for the common EGFR mutations in humans and formulated a multi-peptide vaccine (E^mut Vax) targeting the EGFR L858R, T790M, and Del19 mutations. …”

Presentation_1_Indirect influence of soil enzymes and their stoichiometry on soil organic carbon response to warming and nitrogen deposition in the Tibetan Plateau alpine meadow.pd... by Xiang Xuemei (18392970)

“…Furthermore, warming and nitrogen deposition altered soil bacterial community composition, specifically Gemmatimonadota and Nitrospirota, resulting in a positive impact on soil enzyme activity, particularly soil alkaline phosphatase and β-xylosidase, and enzyme stoichiometry, including N:P and C:P ratios. …”

Image1_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.TIF by Yan Zhou (6523)

“…Among the many biomarkers predicting the efficacy of NAC, immune-related biomarkers, such as immune-related genes and tumor-infiltrating lymphocytes (TILs), play a key role.</p><p>Methods: We analyzed gene expression from several datasets in the Gene Expression Omnibus (GEO) database and evaluated the relative proportion of immune cells using the CIBERSORT method. …”

Data_Sheet_1_Comparative transcriptome analysis of MDBK cells reveals that BoIFN-γ augmented host immune responses to bovine herpesvirus 1 infection.docx by Bo Jiang (76119)

“…Ιnterferon-gamma (IFN-γ) is a pleiotropic cytokine with antiviral activity that modulates the innate and adaptive immune responses. …”

Image1_Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.TIF by Junyu Han (13232310)

“…</p><p>Conclusion: This study demonstrated the functional role of the ARS/miR-29b-3p/HMCN1 axis in alleviating myocardial I/R injury, which provided a new direction for myocardial I/R injury therapy.…”

Image_2_PTEN Inhibition Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury Through PTEN/E2F1/β-Catenin Pathway.jpeg by Dan Zhao (285025)

“…<p>Intracerebral hemorrhage (ICH) is a subtype of stroke with highest mortality and morbidity. …”

Curcumin exerts anti-inflammatory and vasoprotective effects through amelioration of NFAT-dependent endothelin-1 production in mice with acute Chagas cardiomyopathy by Matías Hernández (5527544)

“…<div><p> BACKGROUND The anti-inflammatory and cardioprotective properties of curcumin (Cur), a natural polyphenolic flavonoid isolated from the rhizomes of Curcuma longa, are increasingly considered to have beneficial effects on the progression of Chagas heart disease, caused by the protozoan parasite Trypanosoma cruzi. …”

Image_3_Identification of subclusters and prognostic genes based on glycolysis/gluconeogenesis in hepatocellular carcinoma.tif by Dan Chen (32468)

“…The study also identified five intersecting DEGs from candidate genes in TCGA, GSE14520, and GSE141198 as prognostic genes, which had a protective role in HCC patient prognosis. Compared with the control group, the prognostic genes all showed decreased expression in HCC patients in RT-qPCR and Western blot analyses. …”

Table_2_Characterization and spoilage potential of Bacillus cereus isolated from farm environment and raw milk.DOCX by Lu Meng (289653)

“…This study addresses the biodiversity, toxicity, and proteolytic activity of B. cereus sl from 82 environmental samples and 18 raw bovine milk samples from a dairy farm in the region of Tianjin. In sum, 47 B. cereus sl isolates were characterized through biochemical tests, 16S rRNA gene sequencing, and panC gene analysis. …”

Supplementary Material for: Changes in QT Interval in Maintenance Hemodialysis Patients: Pre-Dialysis, One Hour after Initiation of Dialysis, and Post-Dialysis by Nguyen V.T. (14858983)

“…<b><i>Methods:</i></b> An observational prospective study was conducted, including 61 patients, on thrice-weekly MHD ≥3 months, and without acute diseases, at the Nephrology-Dialysis Department of a tertiary hospital in Vietnam. The exclusive criteria were atrial fibrillation, atrial flutter, branch block, prolonged QT recorded in medical history, and taking antiarrhythmic drugs lengthening QT interval before entering the study. …”

Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation by Xinhua Yan (541869)

Image_1_Calcium-Binding Protein S100P Promotes Tumor Progression but Enhances Chemosensitivity in Breast Cancer.JPEG by Yizi Cong (9377933)

“…</p>Conclusion<p>S100P promotes the aggressive properties of breast cancer cells and may be considered as a promising therapeutic target. Moreover, S100P can be used to predict the therapeutic effect of chemotherapy in HER2+ breast cancer patients.…”

Unique Behavioral and Neurochemical Effects Induced by Repeated Adolescent Consumption of Caffeine-Mixed Alcohol in C57BL/6 Mice by Meridith T. Robins (3159948)

“…To determine changes in neurological activity resulting from adolescent exposure, we monitored changes in expression of the transcription factor ΔFosB in the dopaminergic reward pathway as a sign of long-term increases in neuronal activity. …”

Image_2_Effect of four fluoroquinolones on the viability of bladder cancer cells in 2D and 3D cultures.tif by Tomasz Kloskowski (622176)

“…</p>Results and Discussion<p>All tested fluoroquinolones in 2D culture decreased the viability of both tested cell lines in a dose- and timedependent manner. …”

Pharmacokinetics and pharmacodynamics after treatment of DIO-mice with HI, X10 and IGF-1 by sc injection. by Henning Hvid (486358)

“…<p>A: Plasma concentrations measured in mice treated with HI, X10 or IGF-1. …”

Plant Food Delphinidin-3-Glucoside Significantly Inhibits Platelet Activation and Thrombosis: Novel Protective Roles against Cardiovascular Diseases by Yan Yang (33204)

“…Dp-3-g also significantly inhibited thrombus growth in a carotid artery thrombosis model. To elucidate the mechanisms, we examined platelet activation markers via flow cytometry and found that Dp-3-g significantly inhibited the expression of P-selectin, CD63, CD40L, which reflect platelet α- and δ-granule release, and cytosol protein secretion, respectively. …”