Low-Molecular Weight Heparin Increases Circulating sFlt-1 Levels and Enhances Urinary Elimination by Henning Hagmann (511941)

“…<div><p>Rationale</p><p>Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. …”

DataSheet_1_SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals.zip by Yi-Kong Lin (12882812)

“…</p>Results<p>Increased estrogen-estrogen receptor (ER) α signaling and decreased progesterone receptor isoform B (PRB) expression synergistically led to a hypo-autophagy state in eESCs, which further inhibited the apoptosis of eESCs. …”

Inflammasome elements are important for TIN progression, and inhibition of the xanthine oxidoreductase system attenuates the development of this disease. by Matheus Correa-Costa (119464)

“…<p>Control, WT and ASC and Caspase-1 KO animals were evaluated for (A) serum creatinine levels (ANOVA test - p<0.0001, with Tukey post test – p<0.001 vs. …”

Limited detection of small (≤ 10 mm) colorectal liver metastasis at preoperative CT in patients undergoing liver resection by Yousun Ko (4688230)

“…Nodules were matched between pathology reports and prospective CT reports following a predefined algorithm. Per-nodule sensitivity of CT was calculated by nodule-size category. …”

Table_1_Predicting Treatment Response of Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Using Amide Proton Transfer MRI Combined With Diffusion-Weighted Imaging.do... by Weicui Chen (11058369)

“…</p>Conclusion<p>The combination of APTw and DWI may serve as a noninvasive biomarker for evaluating and identifying response to NCRT in LARC patients.…”

DataSheet_2_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.pdf by Yuan Gao (159945)

“…Inhibition of miR-222-3p significantly suppressed the migration of B-CPAP and induced a mesenchymal-epithelial transition (MET) phenotype via the Snail transcription factor. …”

Image_2_Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.TIF by Leigh Dairaghi (5591222)

“…We show that in mouse: (1) both OECs and GnRH cells express ApoER2, VLDLR and Dab1, and (2) GnRH neurons and OECs show a normal distribution in the brain of two mutant reeler lines. …”

Table1_Geochemistry of Formation Water and Its Implications for Petroleum Source Rocks in the Fengcheng Formation, Mahu Depression, Xinjiang, China.xlsx by Jian Wang (5901)

“…From the first member to the third member of the formation, the salinity first increases and then decreases. This low-high-low trend corresponds to the initial stage of alkaline lake development followed by strong alkali formation and a final stage of water retreat. …”

Table_2_LncRNA TCF7 Promotes Epithelial Ovarian Cancer Viability, Mobility and Stemness via Regulating ITGB8.docx by Changlei Su (11717234)

“…It also correlates with advanced tumor features and poor prognosis in EOC, implying its potential as a target for EOC treatment.</p>…”

Image_2_Comprehensive Analysis of Long Non-coding RNA Modulates Axillary Bud Development in Tobacco (Nicotiana tabacum L.).JPEG by Lin Wang (11986)

“…By lncRNA transcriptomes of axillary buds in topped and untopped tobacco plants, we identified a total of 13,694 lncRNAs. LncRNA analysis indicated that the promoted growth of axillary bud by topping might be partially ascribed to the genes related to hormone signal transduction and glycometabolism, trans-regulated by differentially expressed lncRNAs, such as MSTRG.52498.1, MSTRG.60026.1, MSTRG.17770.1, and MSTRG.32431.1. …”

Cytokine Effects on Gap Junction Communication and Connexin Expression in Human Bladder Smooth Muscle Cells and Suburothelial Myofibroblasts by Marco Heinrich (152162)

“…</p> <h3>Conclusions/Significance</h3><p>Our finding of specific cytokine effects on GJIC support the notion that cytokines play a pivotal role for pathophysiology of OAB and IC. …”

<i>Toxoplasma gondii</i> 70 kDa Heat Shock Protein: Systemic Detection Is Associated with the Death of the Parasites by the Immune Response and Its Increased Expression in the Brai... by Paulo Victor Czarnewski Barenco (560371)

“…<div><p>The heat shock protein of <i>Toxoplasma gondii</i> (<i>Tg</i>HSP70) is a parasite virulence factor that is expressed during <i>T. gondii</i> stage conversion. …”

Presentation acuity & symptomatology. by Tia S. Sutton (16985926)

“…The aim of this study was to determine if procedural suspension due to the COVID-19 pandemic was associated with an increased proportion of acute presentations or more advanced stage at diagnosis for patients with rectal cancer. We conducted a single-center, retrospective review of adult patients with new or recurrent rectal adenocarcinoma from 2016–2021. …”

image1_Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson’s Disease Model.tif by Shuxuan Huang (5869745)

“…Taken together, our data indicated that BBR prevents NLRP3 inflammasome activation and restores autophagic activity to protect DA neurons against degeneration in vivo and in vitro, suggesting that BBR may be a potential therapeutic to treat PD.</p>…”

Growth and Adult Height in Patients with Crohn's Disease Treated with Anti-Tumor Necrosis Factor α Antibodies by Sarah Bamberger (3123876)

“…The purpose of this study was to evaluate growth and adult height in patients with Crohn’s disease taking maintenance infliximab or adalimumab therapy.This university-hospital based retrospective study included 61 patients, with a median follow-up of 2.6 years (2.0; 3.3). 38 patients (62%) reached their adult height. …”

Table_1_5-FU-Induced Upregulation of Exosomal PD-L1 Causes Immunosuppression in Advanced Gastric Cancer Patients.DOCX by Min Zhang (111999)

“…<p>Although the cytotoxic chemotherapeutic agent 5-fluorouracil (5-FU) is generally considered to directly kill cancer cells and exert immunostimulatory effects in advanced gastric cancer, accumulating evidence indicates that it upregulates the expression of PD-L1, a representative immune checkpoint blockade molecule involved in negative regulation of the immune response. …”

Data_Sheet_1_More Than Just Statics: Temporal Dynamic Changes in Inter- and Intrahemispheric Functional Connectivity in First-Episode, Drug-Naive Patients With Major Depressive Dis... by Yu Jiang (234328)

“…We computed the intra- and interhemispheric dynamic FCD (dFCD) using a sliding window analysis to capture the dynamic patterns of functional connectivity. …”

Table4_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.DOCX by Haomiao Li (2743693)

“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”

Clinicopathologic implication of meticulous pathologic examination of regional lymph nodes in gastric cancer patients by Jiwon Koh (3176034)

“…</p><p>Methods</p><p>Four cohorts with a total of 2,309 gastric cancer patients were enrolled. …”

Image_2_Carbon Amendments Influence Composition and Functional Capacities of Indigenous Soil Microbiomes.tif by José Pablo Dundore-Arias (6517574)

“…Mesocosms were established with soil from two field sites varying in soil organic matter content (low organic matter, LOM; high organic matter, HOM), that were amended at intervals over nine months with low or high dose solutions of glucose, fructose, malic acid, a mixture of these compounds, or water only (non-amended control). …”