Image1_Combination of plasma MMPs and PD-1-binding soluble PD-L1 predicts recurrence in gastric cancer and the efficacy of immune checkpoint inhibitors in non-small cell lung cance... by Fumihiko Ando (18512622)

“…The combination of bsPD-L1 and MMPs may represent a non-invasive tool to predict recurrence in GC and the efficacy of ICIs in NSCLC.…”

Impaired Thymic Export and Apoptosis Contribute to Regulatory T-Cell Defects in Patients with Chronic Heart Failure by Ting-Ting Tang (205000)

“…<div><h3>Objective</h3><p>Animal studies suggest that regulatory T (T_reg) cells play a beneficial role in ventricular remodeling and our previous data have demonstrated defects of T_reg cells in patients with chronic heart failure (CHF). …”

Image_4_The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice.pdf by Wenkai Xia (670350)

“…Introduction<p>The atypical chemokine receptor 2 (ACKR2) is a chemokine scavenger receptor, which limits inflammation and organ damage in several experimental disease models including kidney diseases. …”

Schematic model of systematic phosphorus tolerance mechanisms in maize. by Kewei Zhang (568150)

“…Protein expression patterns were indicated by marking protein names and arrows in red (increased expression) or blue (decreased expression). FNR: ferredoxin-NADP reductase; Fd: ferredoxin; ACC: 1-aminocyclopropane-1-carboxylate; ACCO: 1-aminocyclopropane-1-carboxylate oxidase; ADC: arginine decarboxylase; AdoMetsynthase: S-adenosylmethionine synthetase; ADP: adenosine diphosphate; ALA: 5-aminolevulinic acid; APX: ascorbate peroxidase; Arg: arginine; ASA: ascorbic acid; ASP: aspartic acid; ATP: adenosine triphosphate; 1,3-BPGA: 1,3-bisphosphoglycerate; 1,3-BPG: 1,3-bisphosphoglycerate; Cpn21: 10 KD subunit of Chaperonin 21; Cpn60: RuBisCO subunit binding-protein alpha subunit precursor; DAG: diacyl glycerol; dcSAM: S-adenosylmethionine decarboxylation; D-Glu6P: D-Glucose 6-phosphate; DHAR: dehydroascorbate reductase; EF: elongation factors; EMP: Embden-Meyerhof-Parnas pathway; FBP: fructose-1,6-bisphosphate; FBPaldose: fructose-1,6-bisphosphate aldose; FBPase: fructose-1,6-bisphosphatase; FKBP-PPlase: FK506 binding protein peptidyl-prolylisomerases; F6P: fructose-6-phosphate; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GDP-L-Gal: GDP-L-galactose; Glu: glutamic; GME: GDP-D-mannose-3,5-epimerase; G1P: glucose-1-phosphate; G3P: Glyceraldehyde-3-phosphate; G6P: glucose6-phosphate; G6PD: glucose-6-phosphate dehydrogenase; GR: glutathione reductase; GSA: glutamate-1-semialdehyde 2,1-aminomutase; GSSG: oxidized glutathione; GSH: reduced glutathione; GST: glutathione-S-transferase; HMP: hexose-monophophate-pathway; HSP70: heat shock protein 70; L-AsA: L-ascorbic acid; MDHA: monodehydroasorbate; MDHAR: monodehydroasorbate reductase; Met: methionine; NADP-MDH: NADP-Malate dehydrogenase; OAA: oxalacetic acid; PEP: phosphoenolpyruvate; PEPC: phosphoenolpyruvate carboxylase; 2PG: 2-phosphoglycerate; 3PG: 3-phosphoglycerate; 3-PGA: 3-phosphoglycerate; PGK: phosphoglycerate kinase; 6-PG-δ-lactone: 6-phosphoglucono—δ-lactone; 6PGLS: 6-phosphogluconolactonase; PPDK: pyruvate orthophosphate dikinase; Q: coenzyme-Q; QH2: Coenzyme-QH2; RCA: ribulose bisphosphate carboxylase/oxygenase activase; R5P: ribose-5-phosphate; RuBP: Ribulose-1,5-diphosphate; Ru5P: Ribulose-5-phosphate; SAM: s-adenosyl methionine; SBP: sedoheptulose-1,7-diphosphate; SHMT: serine-glycine hydroxymethyltransferase; SOD: superoxide dismutase; S6P: sucrose-6-phosphate; S7P: 7-Phosphosedoheptose; SPDS: spermidine synthase; SPP: sucrose-6-phosphate phosphohydrolase; SQD1: UDP-sulfoquinovose synthase; SQD2: SQDG synthase; SQDG: sulfoquinovosyl diacylglycerol; TCA cycle: Tricarboxylic acid cycle; TK: transketolase; UDPG: uridine diphosphoglucose; UDP-SQ: UDP-sulfoquinovosyl; Xu5P: Xylulose-5-phosphate.…”

Image1_Paleoclimate Records of the Middle Okinawa Trough Since the Middle Holocene: Modulation of the Low-Latitude Climate.jpg by Lei Liu (5074)

“…In contrast, RI-OH temperatures varied from 17.4 to 26.0°C, showing a lower trend than TEX^H₈₆ SSTs. …”

Image_9_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …”

Image_5_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …”

Image5_Combination of plasma MMPs and PD-1-binding soluble PD-L1 predicts recurrence in gastric cancer and the efficacy of immune checkpoint inhibitors in non-small cell lung cance... by Fumihiko Ando (18512622)

“…The combination of bsPD-L1 and MMPs may represent a non-invasive tool to predict recurrence in GC and the efficacy of ICIs in NSCLC.…”

Table_1_Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Acute Kidney Injury: Short-Term Recovery Predicts Long-Term Outcome.docx by Xiaohan Huang (790985)

“…Long-term renal and survival outcomes of these patients were analyzed with a Cox model. The renal endpoint was reaching end-stage renal disease (ESRD), and the survival endpoint was death. …”

Image_11_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …”

Image_2_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg by Chris Marco Mbianda Nana (14492776)

“…This study sought to investigate the involvement of γδ T cells and its subsets in placental Plasmodium falciparum malaria.</p>Methods<p>In a case-control study conducted in Yaoundé, Cameroon from March 2022 to May 2023, peripheral, placental and cord blood samples were collected from 50 women at delivery (29 PM negative: PM- and 21 PM positive: PM+; as diagnosed by light microscopy). …”

Table_1_Analysis on alteration of road traffic casualties in western China from multi-department data in recent decade.xlsx by Jinlong Qiu (9159113)

“…</p>Results<p>The number of traffic accidents and fatalities decreased in low-altitude areas in western China. However, there was a significant increasing trend in the high altitude area. …”

Image_6_The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice.pdf by Wenkai Xia (670350)

“…Introduction<p>The atypical chemokine receptor 2 (ACKR2) is a chemokine scavenger receptor, which limits inflammation and organ damage in several experimental disease models including kidney diseases. …”

Image_13_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …”

DataSheet1_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF by Ying-Hao Hu (11087037)

“…<p>A previously identified anti-rheumatic compound α-mangostin (MAN) possesses notable metabolism regulatory properties. …”

Data_Sheet_1_Intraocular complement activation is related to retinal vascular and neuronal degeneration in myopic retinopathy.docx by Ling Zeng (297715)

“…The levels of complement proteins including C1q, C3, C3b/iC3b, C4, CFB, CFH, C2, C4b, C5, C5a, CFD, MBL and CFI in the aqueous humour were measured using the Luminex Multiplexing system. …”

Downregulation of cancer-associated fibroblast exosome-derived miR-29b-1-5p restrains vasculogenic mimicry and apoptosis while accelerating migration and invasion of gastric cancer... by Chenqu Wu (16842903)

“…<p><b>Background:</b> Cancer-associated fibroblast (CAF) exosomal miRNAs have gradually a hot spot in cancer therapy. This study mainly explores the effect of CAF-derived exosomal miR-29b-1-5p on gastric cancer (GC) cells.…”

Table_1_Sex-specific differences in immunogenomic features of response to immune checkpoint blockade.xlsx by Susan C. Scott (13191618)

Proposed model for extracellular/intracellular Gal-9 <i>trans</i> and <i>cis</i> association with Tim-3 in regulation of monocyte inflammatory cytokine expressions through TLR sign... by Cheng J. Ma (219544)

“…Intracellular Gal-9 also inhibits STAT3 but not STAT-1 phosphorylation, leading to increased IL-12 and decreased IL-23 gene transcriptions. However, intracellular Gal-9 appears to reduce Tim-3 cell surface expression by two distinct mechanisms: <i>cis</i> association/internalization and transcriptional inhibition, through a STAT-3-independent but possibly T-bet-dependent pathway (10). …”

Twsg1 null mice were resistant to podocyte injury. by Sachiko Yamada (527282)

“…<p>(<b>A</b>) Twsg1^+/+:NEP25 and Twsg1^LacZ/LacZ:NEP25 mice were injected with immunotoxin and analyzed seven days later. …”