Potential mechanisms of the decreased efficacy of Nb-015 towards Gamma and XBB variants and Nb-021 towards Omicron variant. by Jing Yang (13969)

IgG binds to GluN2B and decreases CaMKII binding to GluN2B. by Dayton J. Goodell (559732)

“…<p><i>A</i>, Ca²⁺/CaM-stimulated CaMKII binding to GluN2B was tested as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096522#pone-0096522-g001" target="_blank">Figure 1A</a>. …”

Table_1_Prevalence of Plasmid-Mediated Determinants With Decreased Susceptibility to Azithromycin Among Shigella Isolates in Anhui, China.DOCX by Yanyan Liu (171941)

“…Objective<p>The aims of this study were to describe azithromycin (AZM) susceptibility patterns among Shigella isolates in Anhui, China and identify predictors of resistance with mobile element-mediated genes.</p>Methods<p>A total of 517 non-duplicate Shigella isolates (449 S. flexneri and 68 S. sonnei) were collected in the Anhui Province of China from September 2011–September 2015, and screened for the plasmid-mediated genes of decreased susceptibility to AZM (DSA), using polymerase chain reaction amplification and sequencing. …”

Data_Sheet_1_Oral anticoagulant decreases stroke recurrence in patients with atrial fibrillation detected after stroke.pdf by Jin-Yi Hsu (11372153)

Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage by Isobel J. Whitehouse (331843)

“…<div><p>The cellular prion protein (PrP^C) has been implicated in the development of Alzheimer's disease (AD). PrP^C decreases amyloid-β (Aβ) production, which is involved in AD pathogenesis, by inhibiting β-secretase (BACE1) activity. …”

Mobility metric of pre-restriction^a and post-restriction^b periods for the second restriction in two public health units (Toronto, Peel) stratified by neighbor... by Siyi Wang (1412581)

Cerebellar Soluble Mutant Ataxin-3 Level Decreases during Disease Progression in Spinocerebellar Ataxia Type 3 Mice by Huu Phuc Nguyen (110694)

“…Of interest, we observed a tendency for decrease of soluble mutant ataxin-3 only in the cerebellum of transgenic SCA3 mice, one of the most affected brain regions in Spinocerebellar Ataxia Type 3 but not in whole brain tissue, indicative of a brain region selective change in mutant ataxin-3 protein homeostasis.…”

Simulation results predict the role of AC in driving the in-phase behavior and decreasing time delay for inversely out-of-phase behavior. by Lingxia Qiao (19996756)

The time cost and accuracy of state-of-the-art secondary structure prediction methods assessed with PSSM target datasets of decreasing size. by Sheng-Hung Juan (9046515)

“…<p><b>(A)</b> Scorpion. <b>(B)</b> SpineX. <b>(C)</b> Spider2. …”

DataSheet_1_Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer.docx by Damian Kołat (10192637)

“…</p>Conclusion<p>Co-overexpression of WWOX with AP-2α or WWOX with AP-2γ resulted in a net anti-tumor effect. However, considering this research findings and the difference between AP-2α and AP-2γ, we suggest that this similarity is due to a divergent behavior of WWOX.…”

DataSheet_1_Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer.docx by Damian Kołat (10192637)

“…</p>Conclusion<p>Co-overexpression of WWOX with AP-2α or WWOX with AP-2γ resulted in a net anti-tumor effect. However, considering this research findings and the difference between AP-2α and AP-2γ, we suggest that this similarity is due to a divergent behavior of WWOX.…”

DataSheet1_Satisfaction With Governmental Risk Communication Both Increases and Decreases COVID-19 Mitigation Behaviours.docx by Darrick Evensen (13757068)

“…</p><p>Results: Structural equation modelling reveals that whilst perceptions of effective risk communication directly increase behaviours that mitigate COVID-19 health risks, these same perceptions indirectly decrease behaviour frequency via a mediated relationship with societal risk perceptions.…”

DataSheet2_Satisfaction With Governmental Risk Communication Both Increases and Decreases COVID-19 Mitigation Behaviours.docx by Darrick Evensen (13757068)

“…</p><p>Results: Structural equation modelling reveals that whilst perceptions of effective risk communication directly increase behaviours that mitigate COVID-19 health risks, these same perceptions indirectly decrease behaviour frequency via a mediated relationship with societal risk perceptions.…”

Data_Sheet_1_Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice.PDF by Hendrika W. Grievink (6564962)

“…More specifically, we observed a 23% decrease in atherogenic IFNγ-producing splenic CD4⁺ T cells and a 20% decrease in cytotoxic CD8⁺ T cells, whereas atheroprotective IL-10 producing CD4⁺ T cells were increased with 47%. …”

<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets. by Kayvan Zainabadi (502381)

“…<p><b>A)</b> A schematic representing the osteoblast transcriptional regulators and markers examined in this study. …”

Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism by Qing-Yun Guo (2007082)

“…Moreover, the effects of SKF were caused by a decrease in the endogenous levels of allopregnanolone (ALLO), a positive allosteric modulator of the GABA_A receptor. …”

siDDX6 depletion decreases HCV translation, but does not affect miR-122 stimulation of HCV translation. by Adam Huys (425527)

Treatment with BMP-7 decreases expression of M1 macrophage marker, iNOS, as well as pro-inflammatory cytokines. by Crystal Rocher (500661)

“…Histogram <b>C</b> shows quantitative analysis of expression of IL-6 with a significant decrease in the ACM+BMP7 group; n = 5–6. …”

Overexpression of Pif1p Decreases Viability of <i>cdc13–1</i> Cells at Otherwise Permissive Temperatures by Leticia R Vega (75561)

Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring by Ravi F. Sood (263139)

“…</p><p>Results</p><p>Our study population consisted of 538 adults (median age 40 years) who were predominantly White (76%) males (71%) admitted to our center from 2007–2014 with small-to-moderate-sized burns (median burn size 6% total body surface area). Of 2,146 SNPs tested, a rare missense variant in the <i>PTPN5</i> gene (rs56234898; minor allele frequency 1.5%) was significantly associated with decreased severity of post-burn HTS (<i>P</i> = 1.3×10⁻⁶). …”