Maduramicin Inhibits Proliferation and Induces Apoptosis in Myoblast Cells by Xin Chen (14149)

“…Concurrently, maduramicin downregulated protein expression of cyclin D1, cyclin-dependent kinases (CDK4 and CDK6), and CDC25A, and upregulated expression of the CDK inhibitors (p21^Cip1 and p27^Kip1), resulting in decreased phosphorylation of Rb. …”

The Mitochondrial Unfolded Protein Response Protects against Anoxia in <i>Caenorhabditis elegans</i> by Salvador Peña (3147126)

“…“remote”) effects, we found that restricted activation of the UPR^mt in neurons decreased A-R death. However, expression of the <i>atfs-1(gf)</i> mutant in neurons, which resulted in a robust activation of a neuronal UPR^mt, did not upregulate the UPR^mt in distal tissues, nor did it protect the worms from A-R toxicity. …”

Table_1_Vitamin A deficiency in the MENA region: a 30-year analysis (1990–2019).DOCX by Saeid Safiri (3713035)

“…Background<p>Vitamin A deficiency (VAD) is a common micronutrient deficiency that imposes a substantial burden worldwide. …”

Supplemental Figure 1 from BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume by Nicholas Theodosakis (3466673)

Characterization of recent and minimally passaged Brazilian dengue viruses inducing robust infection in rhesus macaques by Maria Beatriz Borges (5142965)

“…Consistent with observations in humans, increased MCP-1, IFN-γ and VEGF-A levels, and transiently decreased IL-8 levels were detected after infection with the selected isolates. …”

Combined loss of Neurog1 and Neurod4 function disrupts habenular neurogenesis. by Caroline Halluin (3158562)

“…The expression of <i>cxcr4b</i> and <i>brn3a</i> appears unaffected in <i>neurod4</i> morpholino injected embryos (C, n = 13/13 and G, n = 14/15) as compared with the expression in wild type (A, n = 9/9 and E, n = 9/9); <i>cxcr4b</i> and <i>brn3a</i> expression is also unaffected in <i>neurog1</i>^{<i>hi1059</i>} mutant (B, n = 12/14 and F, n = 9/11) or only slightly decreased in few cases (respectively n = 2/14 and n = 2/11; data not shown). …”

Image_1_Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis.tif by Hélène Buvelot (11401058)

“…Our results raise the possibility that ROS-dependent downregulation of pyrimidine metabolism might be a survival strategy of S. aureus, allowing colonization through intracellular survival, while decreasing the risk of killing the host through dampened extracellular growth.…”

Image_4_AHR Regulates NK Cell Migration via ASB2–Mediated Ubiquitination of Filamin A.tiff by June Ho Shin (10186634)

“…Our study introduces AHR as a new regulator of NK cell migration, through an AHR-ASB2-filamin A axis and provides insight into a potential therapeutic target for NK cell-based immunotherapies.…”

Data_Sheet_1_LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes.PDF by Yahya Sohrabi (160108)

“…This inflammatory activation by LXR agonists was accompanied by characteristic features of trained innate immunity, such as activating histone marks on inflammatory gene promoters and metabolic reprogramming with increased lactate production and decreased oxygen consumption rate. Mechanistically, LXR priming increased cellular acetyl-CoA levels and was dependent on the activation of the mevalonate pathway and IL-1β signaling. …”

Image_2_AHR Regulates NK Cell Migration via ASB2–Mediated Ubiquitination of Filamin A.tiff by June Ho Shin (10186634)

“…Our study introduces AHR as a new regulator of NK cell migration, through an AHR-ASB2-filamin A axis and provides insight into a potential therapeutic target for NK cell-based immunotherapies.…”

Image_2_Vitamin A deficiency in the MENA region: a 30-year analysis (1990–2019).JPEG by Saeid Safiri (3713035)

“…Background<p>Vitamin A deficiency (VAD) is a common micronutrient deficiency that imposes a substantial burden worldwide. …”

Image_1_Vitamin A deficiency in the MENA region: a 30-year analysis (1990–2019).JPEG by Saeid Safiri (3713035)

“…Background<p>Vitamin A deficiency (VAD) is a common micronutrient deficiency that imposes a substantial burden worldwide. …”

Table_1_Causal relationship between dietary intake and IgA nephropathy: a Mendelian randomization study.xls by Yaping Li (399717)

“…</p>Conclusion<p>Our study provided genetic evidence that alcohol intake frequency was associated with an increased risk of IgAN, while cheese, cereal, and sushi intake were associated with a decreased risk of IgAN. Further investigation is required to confirm these results.…”

Image_3_AHR Regulates NK Cell Migration via ASB2–Mediated Ubiquitination of Filamin A.tiff by June Ho Shin (10186634)

“…Our study introduces AHR as a new regulator of NK cell migration, through an AHR-ASB2-filamin A axis and provides insight into a potential therapeutic target for NK cell-based immunotherapies.…”

Image_2_Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis.tif by Hélène Buvelot (11401058)

“…Our results raise the possibility that ROS-dependent downregulation of pyrimidine metabolism might be a survival strategy of S. aureus, allowing colonization through intracellular survival, while decreasing the risk of killing the host through dampened extracellular growth.…”

Data_Sheet_1_Exosomal hsa-miR199a-3p Promotes Proliferation and Migration in Neuroblastoma.docx by Jing Ma (24574)

“…In summary, our data, for the first time, revealed that exosomal hsa-miR199a-3p could promote tumor proliferation and migration via decreasing NEDD4 expression in NB, suggesting that exosomal hsa-miR199a-3p may be applicated as a fast, easy, and non-invasive detection biomarker and contribute to the development of novel therapeutic strategies for NB in the future.…”

Table_1_Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis.docx by Hélène Buvelot (11401058)

“…Our results raise the possibility that ROS-dependent downregulation of pyrimidine metabolism might be a survival strategy of S. aureus, allowing colonization through intracellular survival, while decreasing the risk of killing the host through dampened extracellular growth.…”

Image_1_AHR Regulates NK Cell Migration via ASB2–Mediated Ubiquitination of Filamin A.tiff by June Ho Shin (10186634)

“…Our study introduces AHR as a new regulator of NK cell migration, through an AHR-ASB2-filamin A axis and provides insight into a potential therapeutic target for NK cell-based immunotherapies.…”

Supplemental Figure 7 from BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume by Nicholas Theodosakis (3466673)

Supplemental Figure 2 from BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume by Nicholas Theodosakis (3466673)