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47461
A proposed model: Different configurations of Pol II with different impact on post-transcriptional stage.
Published 2018“…Thus, the proportion of both configuration 2 and 3 decreases. Consistently, binding of the free Rpb4 and the fusion protein to mRNA is compromised upon over-expressing <i>rpb7-29</i> (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0206161#pone.0206161.g005" target="_blank">Fig 5C</a>, "Rpb2-4 fusion"). …”
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47462
Table_1_Effective Pro-Inflammatory Induced Activity of GALT, a Conserved Antigen in A. Pleuropneumoniae, Improves the Cytokines Secretion of Macrophage via p38, ERK1/2 and JNK MAPK...
Published 2018“…Furthermore, specific inhibitors of the extracellular signal-regulated P38 and JNK MAPKs pathways significantly decreased GALT-induced pro-inflammatory cytokine production, and a western blot assay showed that GALT stimulation induced the activation of the MAPKs pathway. …”
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47463
Presentation_1_OsDIRP1, a Putative RING E3 Ligase, Plays an Opposite Role in Drought and Cold Stress Responses as a Negative and Positive Factor, Respectively, in Rice (Oryza sativ...
Published 2018“…<p>As higher plants are sessile organisms, they are unable to move to more favorable places; thus, they have developed the ability to survive under potentially detrimental conditions. Ubiquitination is a crucial post-translational protein modification and participates in abiotic stress responses in higher plants. …”
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47464
Evaluation of intracellular nickel availability of <i>H</i>. <i>pylori</i> wild type strain and isogenic mutants with a P<i>fecA3</i>::<i>lacZ</i> reporter fusion.
Published 2021“…The expression of the fusion decreases in a NikR-dependent manner with increasing intracellular nickel concentration. …”
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47465
Image_1_A Case Series Clinical Trial of a Novel Approach Using Augmented Reality That Inspires Self-body Cognition in Patients With Stroke: Effects on Motor Function and Resting-St...
Published 2019“…<p>Barring a few studies, there are not enough established treatments to improve upper limb motor function in patients with severe impairments due to chronic stroke. …”
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47466
Hormone Receptor Expression Analyses in Neoplastic and Non-Neoplastic Canine Mammary Tissue by a Bead Based Multiplex Branched DNA Assay: A Gene Expression Study in Fresh Frozen an...
Published 2016“…In case of low hormone receptor expression, IHC is limited and thus is complemented by molecular analyses. In the present study, a multiplex bDNA assay was evaluated as a method for hormone receptor gene expression detection in canine mammary tissues. …”
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47467
Delayed first active-phase meal, a breakfast-skipping model, led to increased body weight and shifted the circadian oscillation of the hepatic clock and lipid metabolism-related ge...
Published 2018“…Moreover, DFAM delayed the surge in body temperature by 4 h and may have contributed to the increase in body weight gain and adipose tissue weight because of decreased energy expenditure. These data indicated a potential molecular mechanism by which breakfast skipping induces abnormal lipid metabolism, which is related to the altered circadian oscillation of hepatic gene expression. …”
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47468
Liver peliosis-like phenotype and thymus degeneration are associated with the doxycycline-induced overall VEGF-A-164 expression in adult pCAGGS-Cre, ROSA26-rtTA-IRES-EGFP, --VEGF-A...
Published 2011“…In addition, the mutant thymus lacks a well-defined cortical layer owing to a dramatically decreased number of basophilic thymocytes seen at higher magnifications (L) compared with (I). …”
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47469
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47470
Data_Sheet_1_Research protocol for bridging research, accurate information and dialogue (BRAID)—clinical trials: a mixed-methods study of a community-based intervention to improve...
Published 2024“…This lack of trust, particularly within underserved communities, contributes to decreased participation in clinical trials and a lack of representation in the data. …”
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47471
Image1_Efficacy of a vaginal suppository formulation prepared with Acacia arabica (Lam.) Willd. gum and Cinnamomum camphora (L.) J. Presl. in heavy menstrual bleeding analyzed usin...
Published 2024“…</p><p>Results: In the SG and TG, the mean PBLAC score decreased from 635.322 ± 504.23 to 67.70 ± 22.37 and 512.93 ± 283.57 to 97.96 ± 39.25, respectively, at post-intervention (TF3), demonstrating a statistically significant difference (p < 0.001). …”
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47472
Data_Sheet_1_A Multi-Sectoral Approach Improves Early Child Development in a Disadvantaged Community in Peru: Role of Community Gardens, Nutrition Workshops and Enhanced Caregiver-...
Published 2020“…Through the “step-by-step” approach, caregivers in IC gained skills in gardening, conscious nutrition and parenting that reduced the risk of food insecurity [Adjusted Risk Ratio = 0.20 (95% CI: 0.08–0.51)] and language delay [0.39 (0.19–0.82)] but not motor or social/cognitive delay. Use of a multiple micronutrient supplement decreased the risk of motor delay [0.12 (0.03–0.56)], but more pets were associated with higher risk of motor [3.24 (1.47–7.14)] and social/cognitive delay [2.72 (1.33–5.55)], and of food insecurity [1.73 (1.13–2.66)].…”
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47473
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47474
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47475
Fish Oil Supplements Lower Serum Lipids and Glucose in Correlation with a Reduction in Plasma Fibroblast Growth Factor 21 and Prostaglandin E2 in Nonalcoholic Fatty Liver Disease A...
Published 2015“…</p><p>Trial Registration</p><p><a href="http://www.chictr.org/en/proj/show.aspx?…”
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47476
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47477
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47478
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47479
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47480
Effect of target number magnitude, and difference in magnitude between target and distractor numbers (numerical distance) on reaction time.
Published 2022“…Reaction time increased (i.e. participants took more time to respond) when the difference in magnitude between the numbers decreased, being slowest to react for a difference of 1 unit, and fastest to react for a difference of 7 units as indicated by the respective coloured lines. …”