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49681
Mice deficient in NKLAM have attenuated inflammatory cytokine production in a Sendai virus pneumonia model
Published 2019“…<div><p>Recent studies have begun to elucidate a role for E3 ubiquitin ligases as important mediators of the innate immune response. …”
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49682
Improving Degradation Efficiency of Organic Pollutants through a Self-Powered Alternating Current Electrocoagulation System
Published 2021“…Moreover, the removal efficiency can be further enhanced by decreasing the frequency AC, in which a 5.7-fold improvement was achieved at 0.2 Hz compared to DC at 1.8 Hz. …”
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49683
Image2_The light-independent locomotion response to a static magnetic field in Xenopus tadpoles.TIF
Published 2022“…We have previously reported that the physical performance of mice decreased after 1 month of exposure to a hypomagnetic field, which probably includes a light-independent mechanism. …”
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49684
Data_Sheet_1_Mapping of a Regulatory Site of the Escherichia coli ADP-Glucose Pyrophosphorylase.PDF
Published 2019“…Other potent activator analogs include 1,6-hexanediol bisphosphate (HBP) and pyridoxal 5′-phosphate (PLP). Recently, a crystal structure with FBP bound was reported (PDB ID: 5L6S). …”
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49685
Image_1_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.TIFF
Published 2019“…<p>Postoperative delirium is a frequent and debilitating complication, especially amongst high risk procedures such as orthopedic surgery, and its pathogenesis remains unclear. …”
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49686
Ecto-5′-Nucleotidase: A Candidate Virulence Factor in <em>Streptococcus sanguinis</em> Experimental Endocarditis
Published 2012“…In the absence of <em>nt5e</em>, <em>S. sanguinis</em> caused IE (4 d) in a rabbit model with significantly decreased mass of vegetations (P<0.01) and recovered bacterial loads (log<sub>10</sub>CFU, P = 0.01), suggesting that Nt5e contributes to the virulence of <em>S. sanguinis</em> in vivo. …”
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49687
Image_9_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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49688
Functional Characterization of an <em>Aspergillus fumigatus</em> Calcium Transporter (PmcA) that Is Essential for Fungal Infection
Published 2012“…The <em>pmcA-C</em> genes have decreased mRNA abundance into the alveoli in the <em>ΔcalA</em> and <em>ΔcrzA</em> mutant strains. …”
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49689
Image_10_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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49690
How is Herstatin, a tumor suppressor splice variant of the oncogene <i>HER2</i>, regulated?
Published 2017“…However, using RNase-assisted RNA chromatography, followed by mass spectrometry, we identified six RNA-binding proteins (splicing factors) that bind to RNA sequences surrounding exon 8/intron 8 and intron 8/exon 9 boundaries; these included hnRNP I, H1, D, A2/B1 and hnRNPA1 plus the SR protein SRSF1. Specifically, overexpression of hnRNP A1 significantly increased retention of intron 8 resulting in higher levels of Herstatin in SKBR3 breast cancer cells whereas SRSF1 only had a marginal effect in decreasing Herstatin but increased exogenous HER2 levels under these experimental conditions. …”
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49691
Image_6_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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49692
Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation
Published 2012“…<div><p>Glioblastoma (GB) is a highly invasive and lethal brain tumor due to its universal recurrence. …”
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49693
Image_3_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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49694
Repetitive Transcranial Magnetic Stimulation in Cervical Dystonia: Effect of Site and Repetition in a Randomized Pilot Trial
Published 2015“…</p><p>Trial Registration</p><p>ClinicalTrials.gov <a href="https://clinicaltrials.gov/ct2/show/NCT01859247" target="_blank">NCT01859247</a></p></div>…”
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49695
Data_Sheet_1_Autonomic Nervous System Function in Anorexia Nervosa: A Systematic Review.docx
Published 2021“…The current review aimed to synthesize the evidence of basal ANS function in individuals with a current diagnosis of AN and those with a previous diagnosis who had achieved weight restoration, as compared to controls.…”
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49696
Table_2_Identification and Characterization of Circular RNA as a Novel Regulator and Biomarker in Preterm Birth.DOCX
Published 2020“…<p>Preterm birth (PTB), as the leading cause of neonatal death, is a severe threat to maternal–fetal health. The diagnosis and treatment of PTB are difficult as its underlying mechanism still unknown. …”
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49697
Effects of UBE3A on Cell and Liver Metabolism through the Ubiquitination of PDHA1 and ACAT1
Published 2023“…Furthermore, a high-fat diet suppressed the expression of UBE3A in the mouse liver, which was associated with increased ACAT1 protein levels, while forced expression of UBE3A in the mouse liver resulted in decreased ACAT1 protein contents. …”
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49698
A review of algal toxin exposures on reserved federal lands and among trust species in the United States
Published 2021“…<p>Associated health effects from algal toxin exposure are a growing concern for human and animal health. …”
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49699
Curcumin affects the brain amyloid deposition histology patterns as a function of <i>Drosophila</i> genotype.
Published 2012“…DAPI staining from regions with widespread p-FTAA-positive aggregates were decreased. (K–O) Aβ<sub>1–42 E22G</sub> expressing flies at day 0, day 5, and day 10, showed a spot-like staining from both p-FTAA and the Aβ specific antibody, but a weaker p-FTAA staining was apparent (c.f. …”
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49700
Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population
Published 2022“…Maternal (n = 167) and infant (n = 172) toenail and placenta (n = 115) samples for prenatal Pb exposure were obtained from participants in a US birth cohort, and methylation and hydroxymethylation data were quantified using the Illumina Infinium MethylationEPIC BeadChip. …”