A Meta-Analysis of <em>Caspase 9</em> Polymorphisms in Promoter and Exon Sequence on Cancer Susceptibility by Wei Xu (28953)

“…Polymorphisms in promoter and exon of <em>caspase 9</em> were shown to confer genetic susceptibility to multiple cancers, but the results were inconsistent. To accomplish a more precise estimation of the relationship, a meta-analysis was performed.…”

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation by Asya Rolls (84466)

“…Using the chimeric mice we found that the immediate inhibition of CSPG production caused a dramatic effect on the spatial organization of the infiltrating myeloid cells around the lesion site, decreased insulin-like growth factor 1 (IGF-1) production by microglia/macrophages, and increased tumor necrosis factor alpha (TNF-α) levels. …”

Monitoring Repair of UV-Induced 6-4-Photoproducts with a Purified DDB2 Protein Complex by Matija Dreze (515840)

“…The signals obtained with the DDB2 proteo-probe and with the antibody against (6-4)PPs decreased in a nearly identical manner. Since (6-4)PPs are repaired only by nucleotide excision repair (NER), our results strongly suggest the DDB2 proteo-probe hybridizes to DNA containing (6-4)PPs and allows monitoring of their removal during NER. …”

Exploring Geographic Variability in Cancer Prevalence in Eastern Morocco: A Retrospective Study over Eight Years by Manal Elidrissi Errahhali (2576014)

“…The ROC is the only hospital specialized in cancer care in Eastern Morocco.</p><p>Results</p><p>A total of 8,508 cases of cancer were registered among residents in Eastern Morocco, with a female to male ratio of 2.1. …”

Data Sheet 2_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.docx by Waner Wang (17773704)

“…</p>Aims<p>The evaluation system aims to provide a foundation and recommendations for optimizing the allocation of hospital nursing human resources by providing data-driven insights to guide staffing decisions. …”

Table1_Changes in carotid artery texture by ultrasound and elastin features in a murine model.xlsx by Carol Mitchell (3525455)

“…We performed this study to examine how grayscale ultrasound texture features and elastin fibers change in plaque-free segments of the arterial wall in a murine model prone to atherosclerosis.</p>Methods<p>A total of 10 Apoe^tm1Unc/J mice (n = 5 male, n = 5 female) were imaged at 6, 16, and 24 weeks of age. …”

Data Sheet 1_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.pdf by Waner Wang (17773704)

“…</p>Aims<p>The evaluation system aims to provide a foundation and recommendations for optimizing the allocation of hospital nursing human resources by providing data-driven insights to guide staffing decisions. …”

Data_Sheet_1_Serotonin Alters the Phase Equilibrium of a Ternary Mixture of Phospholipids and Cholesterol.docx by Oskar Engberg (1620424)

“…We studied the lipid structure and packing of a ternary membrane mixture consisting of palmitoyl-oleoyl-phosphatidylcholine, palmitoyl-sphingomyelin, and cholesterol at a molar ratio of 4/4/2 in the absence and in the presence of 5-HT, using a combination of solid-state ²H NMR, atomic force microscopy, and atomistic molecular dynamics (MD) simulations. …”

Image_2_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.tiff by Florence Jeny (4978466)

“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”

Table_4_HAUS5 Is A Potential Prognostic Biomarker With Functional Significance in Breast Cancer.xlsx by Zhijian Huang (1649578)

“…BRCA cells’ capacity to proliferate was decreased when HAUS5 was knocked down.</p>Conclusion<p>These findings show that HAUS5 is a positive regulator of BRCA progression that contributes to BRCA cells proliferation. …”

Prognostic value of systemic immune-inflammation index in cervical cancer: a systematic review and meta-analysis by Qin Zhan (807877)

“…Our findings indicate that, in contrast to those with low SII, patients exhibiting high SII levels experienced reduced overall and progression-free survival rates, along with a decreased likelihood of attaining complete remission. …”

Effect of <i>OVOS2</i> downregulation on cell proliferation, cell cycle, and apoptosis of A375. by Ying-Xue Huang (5130974)

“…The proliferative rate at 72 h significantly decreased in A375/<i>OVOS2</i>–shRNA compared with that in A375/NC–shRNA and untreated A375 cell groups (**<i>P</i> < 0.01, rANOVA, LSD multiple comparison). …”

Image_6_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.tiff by Florence Jeny (4978466)

“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”

Table_1_Ventricular Myocardial Deformation in Fetuses With Tetralogy of Fallot: A Necessary Field of Investigation.DOCX by Xiaoyan Song (2887361)

“…This study aimed to assess biventricular myocardial deformations in fetuses with TOF compared with normal fetuses.</p><p>Methods: A retrospective cohort study of fetuses with TOF and gestational age (GA)-matched controls was conducted at a single tertiary referral center from 2014 to 2020. …”

DNA Repair Gene XRCC1 Polymorphisms, Smoking, and Bladder Cancer Risk: A Meta-Analysis by Shan Li (110392)

“…<div><p>Background and Objective</p><p>The X-ray repair cross-complementing group 1 (XRCC1) protein plays a crucial role in base excision repair (BER) pathway by acting as a scaffold for other BER enzymes. …”

Cost-effectiveness of a collaborative care model among patients with type 2 diabetes and depression in India by Karl M. F. Emmert-Fees (13106805)

“…</p> <p><strong>Research Design and Methods</strong></p> <p>We performed a within-trial cost-effectiveness analysis of a 24-month parallel, open-label, pragmatic randomized clinical trial at four urban clinics in India from multipayer and societal perspectives. …”

Image_1_Neuroinflammation in early, late and recovery stages in a progressive parkinsonism model in rats.TIF by Debora M. G. Cunha (13432077)

“…Repeated treatment with a low dose of reserpine—inhibitor of VMAT2—has been proposed as a progressive pharmacological model of PD. …”

The urine metabolome differs between lean and overweight Labrador Retriever dogs during a feed-challenge by Josefin Söder (4183498)

“…After overnight fasting, a voided morning urine sample was collected. Dogs were then fed a high-fat mixed meal and postprandial urine was collected after 3 hours. …”

Supplementary Material for: Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage by Kolkhof P. (7545230)

“…Treatment with finerenone and the low-dose combination significantly decreased systolic blood pressure after 5 weeks. There was a dose-dependent protection from cardiac and kidney fibrosis and vasculopathy with both agents, while low-dose combination therapy was more efficient than the respective monotherapy dosages on most cardiorenal histology parameters. …”

Image_1_HAUS5 Is A Potential Prognostic Biomarker With Functional Significance in Breast Cancer.tif by Zhijian Huang (1649578)

“…BRCA cells’ capacity to proliferate was decreased when HAUS5 was knocked down.</p>Conclusion<p>These findings show that HAUS5 is a positive regulator of BRCA progression that contributes to BRCA cells proliferation. …”