Image 9_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.tif by Hong-Xing Li (316258)

“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”

DataSheet1_Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway.ZIP by Ting Zeng (1521649)

“…Transcriptome sequencing and bioinformatics analysis results showed that in cobll1a knockout group, the expression level of genes in the Retinoic Acid (RA) signaling pathway was affected, and the expression level of lipid metabolism-related genes (fasn, scd, elovl2, elovl6, dgat1a, srebf1 and srebf2) were significantly changed (p < 0.01), leading to increased lipid synthesis and decreased lipid catabolism. …”

Data_Sheet_1_Characterisation of the Myocardial Mitochondria Structural and Functional Phenotype in a Murine Model of Diabetic Cardiomyopathy.XLSX by Alex M. Parker (2337379)

“…Diabetic mice exhibited a spectrum of LV mitochondrial changes, including decreased mitochondria area, increased levels of mitochondrial complex-III and complex-V protein abundance, and reduced complex-II oxygen consumption. …”

Ligation of Na, K ATPase β3 subunit on monocytes by a specific monoclonal antibody mediates T cell hypofunction by Nuchjira Takheaw (5447486)

“…<div><p>T cells play a crucial role in orchestrating body immune responses. …”

Table 2_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.docx by Hong Xu (71477)

“…Additionally, these offspring demonstrated a decreased likelihood of elevated homeostasis model assessment of insulin resistance (OR: 0.58; 95% CI: 0.34–0.98; P < 0.05). …”

Table_4_Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent.XLSX by Thuyen Truong (5351702)

“…Consistently, supplementing the resistant strains, GZY803, and SC5314 with peptone, a form of digested peptides, decreased susceptibility to SM21. …”

Data_Sheet_1_An examination from 1990 to 2019: investigating the burden of knee dislocation on a global scale.docx by Cheng Chen (136164)

“…Falls had consistently emerged as the most important cause for both incidence and YLD rates. Additionally, a positive correlation between SDI and the disease burden of knee dislocation was found.…”

Table_3_Gut microbiota composition in travellers is associated with faecal lipocalin-2, a mediator of gut inflammation.csv by Javier Gandasegui (778298)

“…Differential abundance (DA) testing highlighted a microbial profile tied to high LCN2 levels, marked by increased Proteobacteria and Escherichia-Shigella, and decreased Firmicutes, notably Oscillospiraceae. …”

Image 4_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.tif by Hong-Xing Li (316258)

“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”

Supplementary Material for: A Prospective Investigation of Graves' Disease and Selenium: Thyroid Hormones, Auto-Antibodies and Self-Rated Symptoms by Calissendorff J. (4152922)

“…<b><i>Methods:</i></b> We prospectively investigated 38 patients with initially untreated thyrotoxicosis by measuring the thyroid-stimulating hormone (TSH), free thyroxine (FT₄), free triiodothyronine (FT₃), thyroid receptor antibodies and thyroid peroxidase auto-antibodies before medication and at 6, 18 and 36 weeks after commencing treatment with methimazole and levo-thyroxine, with a randomized blinded oral administration of 200 µg Se/day or placebo. …”

Image_1_A Novel Mice Model for Studying the Efficacy and IRAEs of Anti-CTLA4 Targeted Immunotherapy.tif by Shengchao Xu (5715461)

“…Background<p>Patient-derived orthotopic xenograft (PDOX) is a popular animal model for translational cancer research. …”

Dexamethasone therapy prevents delayed neuropsychiatric sequelae after carbon monoxide poisoning: a prospective registry-based study by Sechan Kim (11805470)

“…</p> <p>Early dexamethasone treatment was significantly associated with a decreased incidence of delayed neuropsychiatric sequelae. …”

Supplementary Material for: Introduction of a Quality Improvement Bundle Is Associated with Reduced Exposure to Mechanical Ventilation in Very Preterm Infants by Lo S.C.-Y. (11370777)

“…<b><i>Results:</i></b> The pre-QI and post-QICs included 87 and 98 VPTIs, respectively. The post-QIC had decreased rates of MV in the DR (adjusted odds ratio [aOR] 0.26, 95% confidence interval [CI] 0.09–0.71), in the first 72 h of life (aOR 0.27, 95% CI 0.11–0.62) and during admission (aOR 0.28, 95% CI 0.12–0.66). …”

Data Sheet 1_Changed expression of placental transporters and disrupted epigenetic patterns in a rat model of schizophrenia.pdf by Péter Szatmári (22611392)

“…We hypothesize that the altered protein expression may also be a result of the disease-induced epigenetic pattern changes. …”

Data_Sheet_1_A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception.docx by Hao Zhang (15339)

“…Objective<p>To investigate the temporospatial changes in sympathetic skin response (SSR) and electroencephalogram (EEG) under thermal stimuli and to draw a topographic map of SSR threshold temperature of the oral mucosa.…”

Image 1_Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies.pdf by Zhongmei Fu (11869694)

Image 1_Fatty acid traits mediate the effects of uric acid on cancers: a Mendelian randomization study.pdf by Jianing Li (359834)

“…</p>Results and Discussion<p> Elevated UA levels were associated with an increased risk of in situ neoplasms, cervical cancer, and invasive mucinous ovarian cancer, while they were linked to a decreased risk of cancers of the eye and adnexa, small cell lung cancer, bronchus and lung cancer, respiratory system and intrathoracic organ cancers, as well as lung cancer. …”

Fluctuations in <em>spo0A</em> Transcription Control Rare Developmental Transitions in <em>Bacillus subtilis</em> by Nicolas Mirouze (178835)

“…<div><p>Phosphorylated Spo0A is a master regulator of stationary phase development in the model bacterium <em>Bacillus subtilis</em>, controlling the formation of spores, biofilms, and cells competent for transformation. …”

Image_1_Case report: Rare case of a preoperatively diagnosed spermatic cord paraganglioma and literature review.tif by Yining Hao (10531310)

“…<p>Paraganglioma (PGL) is rare, and PGL that arises from the urogenital system is even rarer. Here we report a case of PGL in spermatic cord and review the relevant literatures. …”

Table_1_Alterations of gut microbiota in cirrhotic patients with spontaneous bacterial peritonitis: A distinctive diagnostic feature.docx by Zumo Zhou (293879)

“…Background<p>Spontaneous bacterial peritonitis (SBP) is a severe infection in cirrhotic patients that requires early diagnosis to improve the long-term outcome. …”