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55561
Image_3_A Novel Mice Model for Studying the Efficacy and IRAEs of Anti-CTLA4 Targeted Immunotherapy.tif
Published 2021“…Background<p>Patient-derived orthotopic xenograft (PDOX) is a popular animal model for translational cancer research. …”
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55562
Table1_Genetic Influence Underlying Brain Connectivity Phenotype: A Study on Two Age-Specific Cohorts.XLSX
Published 2022“…Specifically, it revealed a novel association between the minor allele (G) of rs7937515 and the decreased network segregation measures of the left middle temporal gyrus across young and elderly adults, indicating a consistent genetic effect on brain connectivity across the lifespan. 2) It revealed rs7937515 as a genetic marker for body mass index in young adults but not in elderly adults. 3) It discovered brain network segregation alterations as a potential neuroimaging biomarker for obesity. 4) It demonstrated the hemispheric asymmetry of structural network organization in genetic association analyses and outcome-relevant studies.…”
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55563
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice
Published 2015“…<div><p>Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family DNA helicase, WRN. …”
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55564
Image 10_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.tif
Published 2025“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”
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55565
Image 3_Fatty acid traits mediate the effects of uric acid on cancers: a Mendelian randomization study.pdf
Published 2024“…</p>Results and Discussion<p> Elevated UA levels were associated with an increased risk of in situ neoplasms, cervical cancer, and invasive mucinous ovarian cancer, while they were linked to a decreased risk of cancers of the eye and adnexa, small cell lung cancer, bronchus and lung cancer, respiratory system and intrathoracic organ cancers, as well as lung cancer. …”
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55566
Image 11_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.tif
Published 2025“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”
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55567
Data_Sheet_1_Examining the Benefits of Greenness on Reducing Suicide Mortality Rate: A Global Ecological Study.pdf
Published 2022“…</p>Results<p>The main finding of this study indicates a negative association between greenness exposure and suicide mortality, as greenness significantly decreases the risk of suicide mortality per interquartile unit increment of NDVI (relative risk = 0.69, 95%CI: 0.59–0.81). …”
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55568
Table_2_Assessing the genetic relationship between phimosis and 26 urogenital diseases: a Mendelian randomization study.docx
Published 2024“…</p>Material and method<p>A dual-sample Mendelian randomization (MR) analysis was conducted using the publicly available genome-wide association study (GWAS) data. …”
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55569
Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots
Published 2025“…Such a comprehensive control strategy can inhibit the production of cytotoxic Se species and ROS bursts, significantly increasing the cell viability from 4 to 80% and enhancing the fluorescence of intracellularly synthesized Ag<sub>2</sub>Se QDs by over 8.7 times. …”
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55570
Data_Sheet_1_Ultrasound-guided glenohumeral joint injections for shoulder pain in ALS: A case series.pdf
Published 2023“…Introduction<p>Shoulder pain is a common secondary impairment for people living with ALS (PALS). …”
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55571
Table 1_Application of metagenomics sequencing to diagnose paralytic rabies with stroke-like onset: a case report.docx
Published 2025“…Following admission, the patient exhibited rapidly progressive stroke symptoms, and on the second day, he suffered a sudden respiratory arrest accompanied by a weakened heartbeat and a decreased heart rate. …”
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55572
Data Sheet 3_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf
Published 2025“…Introduction<p>Anomalous congenital bands are a rare cause of intestinal obstruction, with only five previously reported cases involving duodenal obstruction. …”
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55573
Preparation of Silica@Silica Core–Shell Microspheres Using an Aqueous Two-Phase System in a Novel Microchannel Device
Published 2020“…In the present work, a novel microchannel device was developed and used for the preparation of core–shell microspheres combining with a dextran/poly(ethylene glycol) diacrylate (DEX/PEGDA) aqueous two-phase system. …”
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55574
Actin Filaments at the Leading Edge of Cancer Cells Are Characterized by a High Mobile Fraction and Turnover Regulation by Profilin I
Published 2014“…Our results suggest that (i) a high level of actin dynamics (i.e., a large mobile fraction of actin filaments and a fast turnover) is a common characteristic of some cancer cells; (ii) actin polymerization shows a high degree of independence from the presence of extracellular growth factors; and (iii) our results also corroborate the role of Profilin I in regulating actin polymerization, as raising the intracellular levels of Profilin I decreased the mobile fraction ratio of actin filaments and slowed their polymerization rate; furthermore, increased Profilin levels also led to reduced individual cell velocity and directionality.…”
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55575
Table_1_Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent.XLSX
Published 2018“…Consistently, supplementing the resistant strains, GZY803, and SC5314 with peptone, a form of digested peptides, decreased susceptibility to SM21. …”
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55576
Cranial Ontogeny in <em>Stegoceras validum</em> (Dinosauria: Pachycephalosauria): A Quantitative Model of Pachycephalosaur Dome Growth and Variation
Published 2011“…High-resolution CT scans of three frontoparietals reveal that vascularity decreases with size and document a pattern that is consistent with previously proposed histological changes during growth. …”
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55577
Prevalence of clinically validated primary causes of end-stage renal disease (ESRD) in a State Capital in Northeastern Brazil
Published 2018“…A high rate of unknown causes and categorization bias were observed mainly in relation to primary hypertension as a cause of CKD, which affects the overall prevalence of causes of ESRD in patients on dialysis.…”
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55578
Table 1_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.xlsx
Published 2025“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”
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55579
Table_1_Mitochondrial Cytochrome Oxidase Subunit 1: A Promising Molecular Marker for Species Identification in Foraminifera.XLSX
Published 2022“…<p>Traditional morphological methods for species identification are highly time consuming, especially for small organisms, such as Foraminifera, a group of shell-building microbial eukaryotes. …”
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55580
Supplementary Material for: Lifestyle measures and the risk of Metabolic Dysfunction-Associated Steatotic Liver Disease: a cross-sectional study
Published 2025“…Results: The population included (n=58) had a mean age of 62.1±9.2 years, and 58.6% were female. …”