Image_1_Transgenic zebrafish as a model for investigating diabetic peripheral neuropathy: investigation of the role of insulin signaling.TIF by Dong-Won Lee (2208223)

“…Furthermore, we found that the activity of mTOR, a downstream target of IR signaling, was decreased in the PLL ganglion cells of the transgenic zebrafish. …”

Image 2_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.pdf by Yi-Chang Zhao (14080107)

“…Adverse reactions showed a non-significant reduction (RR = 0.65; 95% CI: 0.38–1.11). …”

DataSheet2_Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway.ZIP by Ting Zeng (1521649)

“…Transcriptome sequencing and bioinformatics analysis results showed that in cobll1a knockout group, the expression level of genes in the Retinoic Acid (RA) signaling pathway was affected, and the expression level of lipid metabolism-related genes (fasn, scd, elovl2, elovl6, dgat1a, srebf1 and srebf2) were significantly changed (p < 0.01), leading to increased lipid synthesis and decreased lipid catabolism. …”

DataSheet_1_Integrin-β6 Serves as a Potential Prognostic Serum Biomarker for Gastric Cancer.docx by Zequn Li (5707799)

“…In addition, the serum expression of ITGB6 decreased significantly after radical surgery, and a new rise in serum ITGB6 expression indicated tumor recurrence or progression. …”

Sample level gene expression changes in MSI-H STAD samples with a <i>JAK1</i> frameshift. by Lee A. Albacker (1897015)

“…<p>(A) Heatmap of MSI-H, STAD tumors (columns). Marker rows: 1) Samples with a <i>JAK1</i> frameshift are denoted in green. 2) IFN Response, after <i>JAK1</i> frameshift samples are ordered by IFN Response. 3) Log10 of <i>JAK1</i> expression. 4) <i>JAK1</i> frameshift (FS) MAF. …”

Image 2_Fatty acid traits mediate the effects of uric acid on cancers: a Mendelian randomization study.pdf by Jianing Li (359834)

“…</p>Results and Discussion<p> Elevated UA levels were associated with an increased risk of in situ neoplasms, cervical cancer, and invasive mucinous ovarian cancer, while they were linked to a decreased risk of cancers of the eye and adnexa, small cell lung cancer, bronchus and lung cancer, respiratory system and intrathoracic organ cancers, as well as lung cancer. …”

Investigation of Observational Techniques Ergonomic Risk Assessment of Work-Related Musculoskeletal Disorders among Farmers - A Systematic Review by Adel Mazloumi (10037882)

“…Various ergonomic risk evaluation techniques have been created for industrial fields, but there is a shortage of specific techniques for farming occupations. …”

Charge Density-Regulated Microchannel-Based Electrochemiluminescence Sensor for Hydrogen Sulfide Detection with a Highly Efficient Accumulation Strategy by Yanling Huang (577654)

“…The interaction of azide groups and hydrogen sulfide served as a research model. Hydrogen sulfide can react with the negatively charged azide groups in the microchannel surface to produce positively charged amino groups, decreasing the negative charge density of the microchannel and thus altering the ionic current and ECL intensity. …”

Physiological and Molecular Responses of a Marine Copepod Under Multigenerational Exposure to Coastal Warming and Mercury at an Environmentally Realistic Concentration by Zhuoan Bai (14642500)

“…In this work, we investigated how a warmer temperature (26 °C) and mercury pollution (1 μg/L) affect the marine copepod Tigriopus japonicus across three generations (F0–F2). …”

Image_2_Molecular cloning and functional analysis of a plastidial ω3 desaturase from Emiliania huxleyi.TIF by Kaiwen Sun (1504108)

“…<p>Emiliania huxleyi is a marine microalga playing a significant ecological and biogeochemical role in oceans. …”

Image_2_TNFR2 Is a Crucial Hub Controlling Mesenchymal Stem Cell Biological and Functional Properties.TIFF by Ghada Beldi (9730292)

“…In this article, we have explored the importance of TNFR2 expression in a series of MSCs’ biological and functional properties. …”

Table 2_Pilot study characterizing a single pooled preparation of equine platelet lysate for nebulization in the horse.docx by Patricia Egli (20420606)

Table_1_Monocyte Transcriptional Profiling Highlights a Shift in Immune Signatures Over the Course of Illness in Schizophrenia.DOCX by Jennifer K. Melbourne (10800639)

“…Specifically, the “M1-like” interferon-gamma signature shows decreased enrichment accompanied by increased enrichment of opposing “M2-like” signatures in participants with a medium illness duration shifting to a strong enrichment of interferon response signatures only in participants with a long illness duration. …”

MaMsb2, a signaling mucin, is involved in conidiation, stress tolerances, and virulence in the entomopathogenic fungus Metarhizium acridum by Kai Jin (20368413)

“…<em>Metarhizium acridum</em>, an entomopathogenic fungus, is a promising biopesticide for agricultural, forestry, and urban pest control. …”

Table_1_Gut microbiota composition in travellers is associated with faecal lipocalin-2, a mediator of gut inflammation.xlsx by Javier Gandasegui (778298)

“…Differential abundance (DA) testing highlighted a microbial profile tied to high LCN2 levels, marked by increased Proteobacteria and Escherichia-Shigella, and decreased Firmicutes, notably Oscillospiraceae. …”

Image_1_TNFR2 Is a Crucial Hub Controlling Mesenchymal Stem Cell Biological and Functional Properties.TIFF by Ghada Beldi (9730292)

“…In this article, we have explored the importance of TNFR2 expression in a series of MSCs’ biological and functional properties. …”

Table_1_Altered resting-state brain functional activities and networks in Crohn’s disease: a systematic review.DOCX by Ling Yang (34478)

“…Background<p>Crohn’s disease (CD) is a non-specific chronic inflammatory disease of the gastrointestinal tract and is a phenotype of inflammatory bowel disease (IBD). …”

Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx by Reema Priyanka Suram (22399759)

“…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …”

Table_1_A Novel Mice Model for Studying the Efficacy and IRAEs of Anti-CTLA4 Targeted Immunotherapy.docx by Shengchao Xu (5715461)

“…Background<p>Patient-derived orthotopic xenograft (PDOX) is a popular animal model for translational cancer research. …”

DataSheet1_Effect of type 2 diabetes on biochemical markers of bone metabolism: a meta-analysis.XLSX by Jie Yang (121778)

“…</p>Conclusion<p>In individuals with T2DM, most bone turnover markers indicated a reduced rate of bone turnover. This reduction can lead to increased bone fragility despite higher bone mineral density, potentially increasing the risk of osteoporosis.…”