The PHD Finger of Human UHRF1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers by Nada Lallous (196880)

“…Indeed, a mutation of the former aspartate disrupts the formation of the complex, while mutating the latter decreases the binding affinity nine-fold.…”

Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation by Xi-Song Ke (231600)

“…The model allows a clearer identification of the molecular mechanisms of EMT and its potential role in malignant transformation.…”

Table_2_SCI1 Is a Direct Target of AGAMOUS and WUSCHEL and Is Specifically Expressed in the Floral Meristematic Cells.XLSX by Joelma O. Cruz (10322258)

“…<p>The specified floral meristem will develop a pre-established number of floral organs and, thus, terminate the floral meristematic cells. …”

Table_1_SCI1 Is a Direct Target of AGAMOUS and WUSCHEL and Is Specifically Expressed in the Floral Meristematic Cells.XLSX by Joelma O. Cruz (10322258)

“…<p>The specified floral meristem will develop a pre-established number of floral organs and, thus, terminate the floral meristematic cells. …”

Presentation 1_Ischemia-reperfusion injury with a model of porcine whole-blood ex-vivo lung perfusion.pptx by Jean-Baptiste Menager (22163560)

“…</p>Results<p>Compared to the short CIT group, the long CIT group had a lower maximum perfusion flow rate (mean difference in % cardiac output, −39%; 95% CI, −66 to −12; P = 0.005) and higher pulmonary vascular resistance (mean difference, 1,077 dyne·s·cm⁻⁵; 95% CI, 685–1,469; P < 0.001). …”

Image 1_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.tif by Hong-Xing Li (316258)

“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”

MiR-106a aggravates sepsis-induced acute kidney injury by targeting THBS2 in mice model by Yezhou Shen (7291235)

“…LPS reduced cell viability and Bcl-2 expression, and increased caspase-3 activity, Bax expression, the content of TNF-α, IL-1β, IL-6. THBS2 was a target of miR-106a. The decreases of caspase-3 activity, TNF-α, IL-1β, IL-6, Bax expression and the increases of cell viability, Bcl-2 expression caused by miR-106a knockdown were reversed when THBS2 silencing in LPS-stimulated TCMK-1 cells. …”

Table_1_Assessing the genetic relationship between phimosis and 26 urogenital diseases: a Mendelian randomization study.xlsx by Wei Li (7081)

“…</p>Material and method<p>A dual-sample Mendelian randomization (MR) analysis was conducted using the publicly available genome-wide association study (GWAS) data. …”

Methylglyoxal-related enzymatic removal and molecular damage in brains of mice undergoing a long-term moderate treadmill running. by Stefano Falone (301445)

“…<p>Immunoreactivity levels against arg-pyrimidine (arg-pyr, panel a) and specific activities of glyoxalase 1 (GLO1, panel b) and glyoxalase 2 (GLO2, panel c) in brain cortices of adult CD1 female mice undergoing a two- or four-month moderate and regular treadmill-based exercise program (E2 or E4, respectively); age-matched sedentary animals (S2, S4) were used as controls (n = 6 per group). …”

Electrical Mapping of Silver Nanowire Networks: A Versatile Tool for Imaging Network Homogeneity and Degradation Dynamics during Failure by Thomas Sannicolo (3239889)

“…Our ability to distinguish defects, inhomogeneities, or inactive areas at the scale of the entire network is therefore a critical issue. We propose one-probe electrical mapping (1P-mapping) as a specific simple tool to study the electrical distribution in these discrete structures. 1P-mapping has allowed us to show that the tortuosity of the voltage equipotential lines of AgNW networks under bias decreases with increasing network density, leading to a better electrical homogeneity. …”

Effect of somatic cell count on milk yield and milk components in Holstein cows in a semi-arid climate in Brazil by José Edmário da Silva (6072149)

“…<div><p>SUMMARY This study aimed to investigate the relationship among somatic cell scores (SCS) and currently selected traits (milk yield, and fat, protein, lactose, total solids and no-fat-solids contents) in Holstein dairy cows in a semi-arid climate. The data were collected from available records of 272 Holstein cows from January 2007 to December 2016. …”

Soluble factors from gingival fibroblasts (GFs) inhibit the differentiation of CD1a⁺ dendritic cells. by Sylvie Séguier (441106)

“…Percentages of CD1a⁺ DC-SIGN⁺ dendritic cells decreased with increasing GF/monocyte ratio. …”

Data_Sheet_2_Sphingomyelin and Medullary Sponge Kidney Disease: A Biological Link Identified by Omics Approach.PDF by Simona Granata (477257)

“…<p>Background: Molecular biology has recently added new insights into the comprehension of the physiopathology of the medullary sponge kidney disease (MSK), a rare kidney malformation featuring nephrocalcinosis and recurrent renal stones. …”

DataSheet2_Effect of type 2 diabetes on biochemical markers of bone metabolism: a meta-analysis.XLSX by Jie Yang (121778)

“…</p>Conclusion<p>In individuals with T2DM, most bone turnover markers indicated a reduced rate of bone turnover. This reduction can lead to increased bone fragility despite higher bone mineral density, potentially increasing the risk of osteoporosis.…”

Risk Analysis of Plausible Incidental Exploitation Rates for the Pacific Sleeper Shark, a Data-Poor Species in the Gulf of Alaska by Dean L. Courtney (2745364)

“…Monte Carlo simulations were implemented with a standard, length-based, age-structured model that was evaluated with forward projection. …”

Data_Sheet_1_Reference Interval for Pulse Oxygen Saturation in Neonates at Different Altitudes: A Systematic Review.docx by Bo Wang (86769)

Are Environmental Levels of Nonsteroidal Anti-Inflammatory Drugs a Reason for Concern? Chronic Life-Cycle Effects of Naproxen in Zebrafish by Susana Barros (586042)

“…An integration of apical endpoints, i.e., survival, growth, and reproduction, with gonad histopathology and gene transcription (RNA-seq) was performed to provide additional insights into the mode of action (MoA) of NPX. NPX decreased zebrafish growth and reproduction and led to histopathological alterations in gonads at concentrations as low as 0.1 μg/L. …”

The Putative Protein Methyltransferase LAE1 of <i>Trichoderma atroviride</i> Is a Key Regulator of Asexual Development and Mycoparasitism by Razieh Karimi Aghcheh (425524)

“…In the presence of light, conidiation was 50% decreased in a <b>Δ</b><i>lae1</i> and 30–50% increased in <i>lae1</i>-overexpressing (OE<i>lae1</i>) strains. …”

Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers by Daniel Nettersheim (2866097)

“…<p dir="ltr">In germ cell tumors (GCT), a growing teratoma during chemotherapy with decreasing tumor markers was defined as ´growing teratoma syndrome` (GTS) by Logothetis et al. in 1982. …”

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination by Monica Ghidinelli (4164244)

“…Lm211 can inhibit Nrg1III by limiting protein kinase A (PKA) activation, which is required to initiate myelination. …”