Image_3_Lutzomyia longipalpis TGF-β Has a Role in Leishmania infantum chagasi Survival in the Vector.JPEG by Tatiana Di-Blasi (4680811)

“…The blockage of the LlTGF-β pathway increased significantly antimicrobial peptides expression and nitric oxide levels in the insect gut, as expected. Both methods led to a decreased L. i. chagasi infection. Our results show that inactivation of the L. longipalpis TGF-β signal transduction pathway reduce L. i. chagasi survival, therefore suggesting that under natural conditions the parasite benefits from the insect LlTGF-β pathway, as already seen in Plamodium infection of mosquitoes.…”

Table_2_Causal associations between gut microbiota and Cholestatic liver diseases: a Mendelian randomization study.XLSX by Jiaqi Yang (4380466)

“…</p>Result<p>This two-sample MR study indicated that the order Bacillales, family Peptostreptococcaceae, family Ruminococcaceae, genus Anaerotruncu was associated with a decreased risk of developing PBC, and that order Selenomonadales, family Bifidobacteriaceae may be factors that increase the risk of PBC. …”

Data from: Making a queen: an epigenetic analysis of the robustness of the honey bee (Apis mellifera) queen developmental pathway by Xu Jiang He (8029184)

“…Specialized castes are considered a key reason for the evolutionary and ecological success of the social insect lifestyle. …”

Rodent control to fight Lassa fever: Evaluation and lessons learned from a 4-year study in Upper Guinea by Almudena Mari Saez (5937806)

“…<i>natalensis</i>, as measured by the trapping success, varied between 3.6 and 16.7% before treatment and decreased significantly to 1–2% after treatment. Individuals in treated villages welcomed the intervention and trapping because mice are generally regarded as a nuisance. …”

Appendicular skeletal muscle mass: A more sensitive biomarker of disease severity than BMI in adults with mitochondrial diseases by Yue Hou (2562085)

“…Altogether, compared with BMI, ASMI is a more sensitive biomarker predicting disease severity of MD, both in MELAS and CPEO patients.…”

Fabrication of Mouse Embryonic Stem Cell-Derived Layered Cardiac Cell Sheets Using a Bioreactor Culture System by Katsuhisa Matsuura (111393)

“…In the present study, we established a cultivation system with suitable conditions for expansion and cardiac differentiation of mES cells by embryoid body formation using a three-dimensional bioreactor. …”

Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin by Éric Bergeron (5663428)

“…<div><p>Crimean Congo hemorrhagic fever virus (CCHFV) is a negative-strand RNA virus of the family <i>Bunyaviridae</i> (genus: <i>Nairovirus</i>). …”

Table_3_Genetic associations between ULK3 and epilepsy: a two-sample Mendelian randomization study.xlsx by Baolai Liu (19369291)

“…</p>Results<p>Our MR analyses revealed a causal relationship where an increased level of ULK3 was associated with a decreased risk of focal epilepsy (odds ratio = 0.92, 95% confidence interval: 0.86–1.00, p = 0.041). …”

DataSheet_1_Lifetime risk and health-care burden of diabetic ketoacidosis: A population-based study.docx by Fahim Ebrahimi (6627524)

“…Objective<p>Diabetic ketoacidosis (DKA) is a life-threatening complication of both type 1 and type 2 diabetes. …”

Table_1_Modeling Soil Responses to Nitrogen and Phosphorus Fertilization Along a Soil Phosphorus Stock Gradient.docx by Lin Yu (221619)

“…<p>In this study, we investigate the responses of soil organic carbon (C) to nitrogen (N) and phosphorus (P) additions along a soil P stock gradient of five beech forest stands in Germany, using a modeling approach. …”

Table_1_Genetic infrapopulation sizes in blood parasites: a pilot quantification of the bottleneck in louse fly vectors.xlsx by Kai Fischer (12841946)

“…They are believed to play a particularly prominent role for parasitic infrapopulations, inhabiting single host individuals, which are often established by very few parasite individuals during transmission. …”

Incidence of HIV-Associated Tuberculosis among Individuals Taking Combination Antiretroviral Therapy: A Systematic Review and Meta-Analysis by Tendesayi Kufa (659563)

Development and Validation of a UPLC-MS/MS Method to Monitor Cephapirin Excretion in Dairy Cows following Intramammary Infusion by Partha Ray (655741)

“…Peak excretion (2.69 mg) was on day 1 following intramammary infusion and decreased sharply thereafter (0.19, 0.19, 0.08, and 0.17 mg on day 2, 3, 4, and 5, respectively) reflecting a quadratic pattern of excretion (Quadratic: <i>P</i> = 0.03). …”

Table1_Impact of systemic lupus erythematosus on cardiovascular morphologic and functional phenotypes: a Mendelian randomization analysis.xlsx by Zishan Lin (14501705)

“…</p>Results<p>SLE exhibited a correlation with increased stroke volume (β_LVSV = 0.007, P = 0.045), regional peak circumferential strain (β_{Ecc_AHA_9} = 0.013, P = 0.002; β_{Ecc_AHA_12} = 0.009, P = 0.043; β_{Ecc_AHA_14} = 0.013, P = 0.006), and global peak circumferential strain of the LV (β_{Ecc_global} = 0.010, P = 0.022), as well as decreased regional radial strain (β_{Err_AHA_11} = −0.010, P = 0.017).…”

Supplementary Materials for Genotypic and phenotypic spectrum and pathogenesis of WNT1 variants in a large cohort of patients with OI / osteoporosis by Jing Hu (14249099)

“…We reported for the first time a decreased β-catenin level in the bone of patient 10 with c.677C>T and c.502G>A compared to the healthy control, which revealed the potential mechanisms of WNT1-induced skeletal phenotypes. …”

Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Image_3_A synonymous mutation in PI4KA impacts the transcription and translation process of gene expression.tif by Kaihui Zhang (2162758)

“…<p>Phosphatidylinositol-4-kinase alpha (PI4KIIIα), encoded by the PI4KA gene, can synthesize phosphatidylinositol-4-phosphate (PI-4-P), which serves as a specific membrane marker and is instrumental in signal transduction. …”

Effects of Successive Rotation Regimes on Carbon Stocks in Eucalyptus Plantations in Subtropical China Measured over a Full Rotation by Xiaoqiong Li (684376)

“…<div><p>Plantations play an important role in carbon sequestration and the global carbon cycle. However, there is a dilemma in that most plantations are managed on short rotations, and the carbon sequestration capacities of these short-rotation plantations remain understudied. …”

Table 3_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Background<p>Osteomyelitis, a persistent inflammatory bone disease, is only partially responsive to conventional antibiotics and surgery. …”

Effect of different phosphorus sources on P-uptake and yield of rice in acidic soil: a study of phosphorus availability dynamics by Sagolshem Kalidas-Singh (14327868)

“…Rhizosphere-based P management has been considered as a means of enhancing PUE in acidic rice soils, but no clear dynamic study on this context. …”