Treatment with SEFA-6179 in mice receiving a high carbohydrate diet (HCD) with intravenous saline or SOLE decreases lipid metabolites involved in lipotoxicity including diacylglycerol, triglycerides, cholesterol, and ceramides. by Bennet S. Cho (6944669)

<i>Nf1</i> OPG mice show decreased spontaneous alternations in a Y-maze but no deficits in spatial working memory or long-term depression (LTD) in hippocampal slices. by David F. Wozniak (78177)

Decreasing rates of disorganised attachment in infants and young children, who are at risk of developing, or who already have disorganised attachment. A systematic review and meta-analysis of early parenting interventions by Barry Wright (313307)

Data_Sheet_1_Low molecular weight heparin decreases mortality and major complication rates in moderately severe and severe acute pancreatitis–a systematic review and meta-analysis.docx by Cristina Patoni (16619856)

“…Randomized controlled trials (RCTs) and observational studies that reported the differences in the outcomes of AP for patients receiving anticoagulants (intervention group) in addition to the standard of care (SOC), compared to patients managed by SOC alone (control group), were eligible. A random-effects model was used to calculate the pooled odds ratios (OR) and mean differences (MD) with the corresponding 95%-confidence intervals (CI). …”

Decreased intracellular replication of <i>S</i>. Typhimurium Δ<i>sucCD</i> and Δ<i>gltA</i> strains during infection of HeLa epithelial cells. by Steven D. Bowden (237943)

Evolutionary dynamics of replicators’ association rate without and with parasites: <i>k</i>_<i>a</i> decreases in the absence of parasites, and evolves to higher values the stronger the parasites. by Enrico Sandro Colizzi (2633266)

Table_1_YTHDF2 Gene rs3738067 A>G Polymorphism Decreases Neuroblastoma Risk in Chinese Children: Evidence From an Eight-Center Case-Control Study.DOC by Huijuan Zeng (6637514)

“…We found that the rs3738067 A>G could decrease neuroblastoma risk [AG vs. AA: adjusted odds ratio (OR) = 0.76, 95% confidence interval (CI) = 0.64–0.90, P = 0.002; AG/GG vs. …”

Phenotypic diversity and drug susceptibility of <i>Trypanosoma cruzi</i> TcV clinical isolates by Luz P. Quebrada Palacio (613253)

“…Benznidazole-resistant BOL-FC10A epimastigotes had decreased expression of Old Yellow Enzyme and cytosolic superoxide dismutase, and overexpression of mitochondrial superoxide dismutase and tryparedoxin- 1, compared to benznidazole-susceptible AR-SE23C parasites. …”

Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene by Melanie S. Flint (2263015)

“…The proteomic results further indicate that exposure to DMBA induces increases in the abundance of CYP1A2 and serine protease inhibitors and decreases the abundance of CYP4 V3. …”

Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene by Melanie S. Flint (2263015)

“…The proteomic results further indicate that exposure to DMBA induces increases in the abundance of CYP1A2 and serine protease inhibitors and decreases the abundance of CYP4 V3. …”

Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene by Melanie S. Flint (2263015)

“…The proteomic results further indicate that exposure to DMBA induces increases in the abundance of CYP1A2 and serine protease inhibitors and decreases the abundance of CYP4 V3. …”

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven <i>Salmonella</i> Typhimurium Host Cell Invasion - Fig 2 by Daniel Andritschke (149523)

“…(H) KEGG pathway mapping of decreasing hits from the Qiagen unpooled <i>S</i>. Tm^SipA siRNA screen. …”

The phosphorylation of FgHapX mediated by the Ser/Thr kinase FgYak1 is required for the transcriptional activity of FgHapX. by Zhihui Wang (88248)

“…<p>(A) The mutations of FgHapX at 245 and 338 from Ser to Ala or loss of FgYak1 led to a decreased phosphorylation level of FgHapX. …”

The extreme N-terminus of TDP-43 is required to repress <i>UNC13A</i> cryptic exon splicing. by Yuka Koike (2249959)

“…Blot provided in Supporting information (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002028#pbio.3002028.s013" target="_blank">S1 Raw images</a>). qRT-PCR (right) analysis shows significantly decreased TDP-43 binding to <i>UNC13A</i> RNA only in the cells expressing GFP-TDP-43_5FL compared with the cells expressing GFP-TDP-43_WT. …”

PXT3003 therapy acting on Pmp22 overexpression and downstream signalling in long-term at 12 weeks. by Thomas Prukop (6236186)

“…At the end of long-term observation, PXT3003 early short-term treatment restored the decreased p-AKT/AKT signalling in CMT1A rats (H; WT controls 1.00±0.17, CMT1A controls 0.38±0.08, CMT PXT3003-3 0.93±0.21) and dose-dependently corrected the disrupted ratio of p-AKT/AKT to p-MAPK/MAPK signalling towards the wildtype situation (I; CMT1A controls 0.30±0.08, CMT PXT3003-1 0.56±0.15, CMT PXT3003-2 0.85±0.13, CMT PXT3003-3 1.36±0.52), which is characterized by a higher relative amount of p-AKT versus p-MAPK. …”

HDACIs That Simultaneously Inhibit HDACs 1 and 6 Showed Greater Antileukemic Activities than HDACIs that Don't at Cmax Concentrations. by Xuelian Xu (229877)

“…The effects of the 3 h and 24 h HDACI treatments on cell proliferation, as reflected by percent decrease of live cells relative to untreated cells (panel E), and apoptosis (panel F) were determined by flow cytometry analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017138#s2" target="_blank">Materials and Methods</a>.…”

The effect of meal frequency in a reduced-energy regimen on the gastrointestinal and appetite hormones in patients with type 2 diabetes: A randomised crossover study by Lenka Belinova (618839)

“…The aim of this secondary analysis was to explore the effect of two hypocaloric diet regimens on fasting levels of appetite and GIHs and on their postprandial responses after a standard meal. It was hypothesized that lower meal frequency in a reduced-energy regimen leading to greater body weight reduction and reduced hunger would be associated with decreased plasma concentrations of GIHs: gastric inhibitory peptide (GIP), glucagon-like peptide-1(GLP-1), peptide YY(PYY), pancreatic polypeptide (PP) and leptin and increased plasma concentration of ghrelin. …”

A. Concise demographic details for each patient included in the study. by Neil K. Jairath (13237338)

Immunoblotting analysis to validate the protein expression shown in Figs 1A, 2A, 4A, 4E, 5B, and S13. by Yongle Zhang (11355546)

Hypothesis 3: The mean difference between “Class 1” (a school attack happens within <i>k</i> kms. of a given school) and “Class 0” (no school attack happens within <i>k</i> kms. of a given school) for increases as the Socioeconomic Risk Score of the region of each school decreases (i.e. the school is in a wealthier neighborhood). by Lirika Sola (21560710)