Data_Sheet_1_An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss.DOCX by Seyed Ali Elahi (11005782)

“…The algorithm iteratively interacts with a finite element (FE) model of a cartilage explant, with and without variable depth to full-thickness defects. …”

Cellular Effects of Bacterial <i>N</i>-3-Oxo-Dodecanoyl-_L-Homoserine Lactone on the Sponge <i>Suberites domuncula</i> (Olivi, 1792): Insights into an Intimate Inter-King... by Johan Gardères (568196)

“…This molecule seemed to inhibit the sponge innate immune system through a decrease of the expression of genes coding for proteins sensing the bacterial membrane: a Toll-Like Receptor and a Toll-like Receptor Associated Factor 6 and for an anti-bacterial perforin-like molecule. …”

Video_2_ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure.MP4 by Anja Schulz-Kuhnt (8803928)

“…Although group-2 innate lymphoid cells (ILC2s) act as crucial initiators of lung inflammation, our understanding of their involvement in the pathogenesis of cystic fibrosis remains incomplete. Here we report a marked decrease of circulating CCR6⁺ ILC2s in the blood of cystic fibrosis patients, which significantly correlated with high disease severity and advanced pulmonary failure, strongly implicating increased ILC2 homing from the peripheral blood to the chronically inflamed lung tissue in cystic fibrosis patients. …”

DataSheet_1_Tryptophan synthase ß subunit 1 affects stomatal phenotypes in Arabidopsis thaliana.pdf by Midori N. Soda (14184509)

“…To elucidate the molecular mechanism of stomatal movements, we performed a genetic screen based on stomatal aperture-dependent weight decrease of detached leaves from EMS-treated Arabidopsis thaliana and isolated a rapid transpiration in detached leaves 2 (rtl2). …”

miR-22 inhibits DCs from expressing IL-6 and driving Th17 cells differentiation. by Xue Liang (449130)

“…The bar plots are expressed in the form of mean±SD. * means a significant decrease appears when compared with the control group (p-value < 0.05, t test), while ** represents a significant increase relative to the control (p-value < 0.05, t test).…”

Relative Energies of α and β Isomers of Keggin Dodecatungstogallate by Karthik M. Sundaram (2652337)

“…This finding is evaluated by analysis of the X-ray crystal structure α-K₂Na₃[GaW₁₂O₄₀]·9.3H₂O [trigonal, space group <i>P</i>3₂21, <i>a</i> = 18.9201(13) Å, <i>b</i> = 18.9201(13) Å, <i>c</i> = 12.5108(12) Å, <i>Z</i> = 3, <i>T</i> = 100(2)K], comparison of the Shannon and Prewitt radii and Pauling electronegativities of Al³⁺ and Ga³⁺, and insight from density functional theory calculations, which predicted <i>E</i>_β − <i>E</i>_α = 0.32 kcal mol^-1.…”

Alterations in tone and FM sweeps evoked activity during repetitive stress. by Ghattas Bisharat (20706928)

“…Activity rates decreased at moderate sound intensities, while activity at high intensities remained comparable to baseline intensities (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003012#pbio.3003012.g002" target="_blank">Fig 2D</a>, 2-way ANOVA, condition F = 16.1, <i>p</i> = 6.02 × 10⁻⁰⁵, nested ANOVA (mouse nested within session) F = 16.1, <i>p</i> = 5.9 × 10⁻⁰⁵, mean ± SE). …”

List of DEGs from iPSC analysis. by Sara Cuvertino (18892069)

“…<div><p>Kabuki syndrome type 1 (KS1) is a neurodevelopmental disorder caused by loss-of-function variants in <i>KMT2D</i> which encodes a H3K4 methyltransferase. …”

Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf by Gufeng Gao (16835753)

“…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). In PASMCs stimulated with PDGF-BB, a similar trend of increased p-PKC, p-IRS-1(Ser318), and p-ERK levels was observed, along with a decrease in IRS-1 expression. …”

Image_2_Organ-Specific Gene Expression Reveals the Role of the Cymbidium ensifolium-miR396/Growth-Regulating Factors Module in Flower Development of the Orchid Plant Cymbidium ensi... by Fengxi Yang (428964)

“…We observed a significant decrease in the transcripts of several CeGRFs in flowers and leaves, indicating a potential role for miR396–GRF module in organ development through the cleavage of distinct CeGRFs. …”

DataSheet_1_Rapid Emergence of T Follicular Helper and Germinal Center B Cells Following Antiretroviral Therapy in Advanced HIV Disease.xlsx by Chun-Shu Wong (6750368)

“…CD4:CD8 and CD4 T- and B-cell PB subsets partly normalized compared to HC post-ART as viral load decreased. Strikingly in LN, ART led to a rapid decrease in interferon signaling pathways and an increase in Tfh, germinal center and IgD^-CD27^- B cells, consistent with histological findings of post-ART follicular hyperplasia. …”

Data_Sheet_1_Detection of COVID-19 epidemic outbreak using machine learning.pdf by Giphil Cho (14129502)

“…</p>Objective<p>In this study, we aimed to propose a machine learning-based method to predict the transmission trend of COVID-19 and a new approach to detect the start time of new outbreaks by analyzing epidemiological data.…”

Effects of TNFR neutralizing antibodies on mTORC1 and caspase activity. by Valentina Guerrini (3396608)

“…Full-length blots are presented in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007223#ppat.1007223.s008" target="_blank">S8 Fig</a>. …”

Types of decisions. by Yael Appelboom (20570815)

“…Mental effort rose from 17h onwards higher values, whereas a decrease in comfortability was seen from 21h onwards.…”

Data_Sheet_1_Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats.docx by Gaudencio Fernández-Miranda (6650009)

“…Quiescent MetS cardiomyocytes showed a decrease in Ca²⁺ spark frequency, amplitude, and spark-mediated Ca²⁺ leak. …”

<i>Lp</i> knockdown significantly impairs oogenesis and affects Vg expression and localization. by Iryna Stryapunina (17867390)

“…(C) Western blot quantification from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011145#pgen.1011145.g001" target="_blank">Fig 1C</a> showing an accumulation of Vg in the fat body and a decrease of Vg in the ovaries upon <i>Lp</i> knockdown; samples of five tissues, three biological replicates (REML variance component analysis: ** = p < 0.01; **** = p < 0.0001). …”

Inclusion and exclusion criteria. by Laurence Weinberg (2960238)

“…Scoping review registered on OSF registries (<a href="https://osf.io/4mg7n" target="_blank">https://osf.io/4mg7n</a>).…”

Table 1_Evaluation of F18 enterotoxigenic Escherichia coli intestinal attachment and early disease onset in nursery pigs.docx by Elizabeth M. Due (22819034)

“…Introduction<p>Enterotoxigenic Escherichia coli (ETEC) is a major cause of post-weaning diarrhea and reduced performance in nursery pigs. …”

DataSheet5_An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages.xlsx by Fei Jing (298892)

“…Fuzheng Huayu (FZHY) formula, a Chinese herbal product, is effective in treating pulmonary fibrosis in our previous study. …”

Knockdown of Ice-Binding Proteins in <i>Brachypodium distachyon</i> Demonstrates Their Role in Freeze Protection by Melissa Bredow (3396572)

“…IBP-knockdown lines also demonstrated a significant decrease in viability following freezing to −8°C, with some lines showing only two-thirds the survival seen in control lines. …”