datasheet1_In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.docx by Dahara Keyse Carvalho Silva (9774635)

“…Also, in vivo treatment of BALB/c mice infected with L. amazonensis resulted in a decrease of lesion size, parasitic load and caused histopathological alterations, when compared to vehicle-treated control. …”

Distinct Peripheral Blood RNA Responses to <em>Salmonella</em> in Pigs Differing in <em>Salmonella</em> Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways by Ting-Hua Huang (192546)

“…We confirmed the activation of two regulatory factors, SPI1 and CEBPB, and demonstrated that expression of miR-155 was decreased specifically in the PS animals. These data provide insight into specific pathways associated with extremes in <em>Salmonella</em> fecal shedding that can be targeted for further exploration on why some animals develop a carrier state. …”

Image_2_Endocannabinoids Produced by White Adipose Tissue Modulate Lipolysis in Lean but Not in Obese Rodent and Human.tiff by Chloé Buch (9093966)

“…In the present study, we used different strategies to acutely increase ECS activity in WAT and tested the consequences on glycerol production as a marker of lipolysis. Treating lean mice or rat WAT explants with JLZ195, which inhibits ECs degrading enzymes, induced an increase in 2-AG tissue contents that was associated with a CB1R-dependent decrease in lipolysis. …”

Image_2_Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors’ Transc... by Weijie Yang (3625022)

“…Mice were treated with a single dose of CTX (100 mg/kg) at post-natal day 21 and sacrificed 47 days later when primordial follicles surviving chemotherapy developed to the antral stage. …”

Ion Transport Analysis of Anion-Exchange Membranes in Various Hydration States: Combining Experiments with Molecular Dynamics Simulation by Yuri Nara (22402134)

“…To overcome these issues, it is crucial to understand how the polymer morphology changes with hydration states and why low humidity conditions lead to a decrease in anion conductivity. In the present study, all-atom molecular dynamics (MD) simulations have been carried out to elucidate the hydration structure of trimethylammonium-substituted polyfluorene (TMA-PF), previously reported by the authors [Nara et al., <i>Polym. …”

Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice by Chi-Cheng Lu (163756)

“…Our results indicated that a concentration-dependent decrease of cell viability was shown in MJ-29-treated cells. …”

Data_Sheet_4_Differential effects on TDP-43, piezo-2, tight-junction proteins in various brain regions following repetitive low-intensity blast overpressure.CSV by Lanier Heyburn (7055039)

“…</p>Methods<p>In this study, using a rodent model of relBOP and western blotting for protein expression we showed the differential expression of various neuropathological proteins like TDP-43, tight junction proteins (claudin-5, occludin, and glial fibrillary acidic protein (GFAP)) and a mechanosensitive protein (piezo-2) in different regions of the brain at different intensities and frequency of blast.…”

Table_2_Conventional-Vincristine Sulfate vs. Modified Protocol of Vincristine Sulfate and L-Asparaginase in Canine Transmissible Venereal Tumor.DOCX by Chanokchon Setthawongsin (6568634)

“…<p>Background: Vincristine (VCR) is a mono-chemotherapy for canine transmissible venereal tumor (CTVT). …”

Table_3_Developmental, Morphological and Physiological Traits in Plants Exposed for Five Generations to Chronic Low-Level Ionising Radiation.XLSX by Nicol M. Caplin (8710839)

“…This is explained by the redundancy and/or degeneracy between biological levels of organization in plants that produces a relatively loose association between genotype and phenotype. …”

Data_Sheet_1_Projecting shifts in the distributions of Chinese endemic vertebrate species under climate and land-use change.pdf by Yiming Deng (2814844)

“…<p>Human-induced climate and land-use change impact species’ habitats and survival ability. A growing body of research uses species distribution models (SDMs) to predict potential changes in species ranges under global change. …”

Data_Sheet_2_Harmful Effect of Rheinheimera sp. EpRS3 (Gammaproteobacteria) Against the Protist Euplotes aediculatus (Ciliophora, Spirotrichea): Insights Into the Ecological Role o... by Carolina Chiellini (6498890)

“…Additionally, TEM investigation showed that when the ciliate culture was inoculated with Tq treatment, both a notable decrease of P. necessarius number and an increase of damaged and degraded mitochondria occur. …”

DataSheet_1_Coastal carbonate system variability along an active lava–seawater interface.docx by David González-Santana (9121751)

“…The evolution of surface and water column physicochemical properties (temperature, salinity, carbonate system variables, and dissolved oxygen) was characterized during 13 visits to the frontal zone of the newly formed deltas. A large volume of hot (50°C measured on November 12th) and high salinity seawater promoted pH values in the frontal zone of 7.0 with important decreases in alkalinity, ΔA_T, and total dissolved inorganic carbon, ΔC_T, that reached 566 and 272 µmol kg⁻¹, respectively. …”

Tumor suppressive properties of OGDHL using stable clone. by Tanusree Sen (119721)

“…<p><b>A.</b> RT-PCR analysis of SiHa cells stably transfected with the mammalian expression vector pcDNA3 with full-length OGDHL cDNA and empty pcDNA3 vector (mock). …”

Model Studies of 6,7-Indolequinone Cofactors of Quinoprotein Amine Dehydrogenases by Yoko Murakami (423119)

“…The electronic effects of the C-4 substituent on the physicochemical properties and reactivity of the 6,7-inodolequinone cofactors (CTQ and TTQ) have extensively been investigated with use of a series of C-4 substituted 6,7-inodolequinone derivatives (<b>1</b>−<b>4</b>). …”

Image_2_Does Stream Water Composition at Sleepers River in Vermont Reflect Dynamic Changes in Soils During Recovery From Acidification?.eps by Jesse R. Armfield (6424550)

“…Although base cations, especially Ca, decrease progressively with time in GW, riparian soils have become more enriched in Ca, due to a mixture of lateral and vertical transfers. …”

Study scheme. by Ayako Shoji (78037)

“…</p><p>Conclusions</p><p>We demonstrated a reduction in the incidence rate of suspected mild cognitive impairment among residents who participated in the CHAP and a decrease in the medical and caregiving costs associated with suspected severe cognitive impairment.…”

Table_5_Research on Dynamic Evolution of Systemic Risk in Chinese Banking System.doc by Hong Fan (146238)

“…The results show that the evolution characteristics of credit risk of 18 real industries can be divided into 4 types which are stability after decline, increase in fluctuation, decrease in fluctuation, and fluctuation. The systemic risk of Chinese banking system with the double risk exposures gradually increased with the evolution of time, and then stabilized at a certain degree. …”

Data_Sheet_1_Long-term effects of chloropicrin fumigation on soil microbe recovery and growth promotion of Panax notoginseng.docx by Xin Wang (91924)

“…Introduction<p>Panax notoginseng is a precious Chinese medicinal material. Soil fumigation can control soil-borne disease and overcome the continuous cropping obstacles of P. notoginseng. …”

Data_Sheet_1_The effect of urban environments on the diversity of plants in unmanaged grasslands in Los Angeles, United States.docx by John English (78856)

“…<p>Urbanization is a strong driver of plant diversity and may have complex effects on developed ecosystems. …”

Asymmetric Hydrogenation of Enamides with Rh-BisP* and Rh-MiniPHOS Catalysts. Scope, Limitations, and Mechanism by Ilya D. Gridnev (1357566)

“…In these monohydrides the Rh atom is bound to the β-carbon. A new effect of the significant decrease of ee was found for the asymmetric hydrogenation of CH₂C(C₆H₄OCH₃-<i>o</i>)NHCOCH₃ (<b>21</b>), when H₂ was substituted for HD or D₂.…”