Supplementary Material for: The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in... by Reuther C. (3593810)

“…In a Western blot analysis of GOT1 cells, NVP-CGM097 caused a dose-dependent increase in the expression of p53 and p21 tumor suppressor proteins and a decrease in phospho-Rb and E2F1. …”

p53 trans-activates the <i>Pax2</i> promoter. by Zubaida Saifudeen (135684)

“…<p><b>A</b>) <i>p53^−/−</i> H1299 cells were co-transfected with a p53 expression plasmid (pCMV-p53) and a 4.1-Pax2-CAT reporter construct. …”

Data_Sheet_2_Personalized surgical planning for coronary bypass graft configurations using patient-specific computational modeling to avoid flow competition in arterial grafts.XLSX by Krish Chaudhuri (13866956)

“…The use of the computational models led to a significant decrease in the selection of unsatisfactory grafting configurations when surgeons employed “anaortic” (21.25% (17/80) vs. 1.25% (1/80), P < 0.001) but not “aortic” techniques (5% (4/80) vs. 0% (0/80), P = 0.64). …”

Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (<i>Ailuropoda melanoleuca</i>) reproductive monitoring by Jella Wauters (1657804)

“…To this extent, six cycles from two female pandas (SB741(1) and SB569(5)) were monitored through urine analysis for oestrogen, progesterone, ceruloplasmin and 13,14-dihydro-15-keto-PGF2a (PGFM). The Pearson’s correlation between creatinine and USpG was high (r = 0.805–0.894; p < 0.01), indicative for a similar performance of both normalisation methods. …”

Arrest and synchronous triggering of ASLV pseudovirus fusion with endosomes using NH₄Cl. by Sergi Padilla-Parra (166100)

“…Removal of NH₄Cl through perfusion with HBSS caused a marked decrease in the GFP signal, but not in DiD fluorescence (middle). …”

Arkadia Ubiquitinates P-Smad2 and Mediates Its Degradation via the Proteasome by Konstantinos J Mavrakis (25033)

“…<div><p>(A and B) IP with anti-Flag antibody from <i>Akd</i>−/− MEFs transiently transfected with various plasmids as indicated, and Western blotted (WB) with anti-P-Smad2, anti-HA, or anti-ubiquitin antibodies. …”

Data_Sheet_4_Personalized surgical planning for coronary bypass graft configurations using patient-specific computational modeling to avoid flow competition in arterial grafts.XLSX by Krish Chaudhuri (13866956)

“…The use of the computational models led to a significant decrease in the selection of unsatisfactory grafting configurations when surgeons employed “anaortic” (21.25% (17/80) vs. 1.25% (1/80), P < 0.001) but not “aortic” techniques (5% (4/80) vs. 0% (0/80), P = 0.64). …”

YorkU.Impermeable/Pond.Oct17-2016 by Numra Shah (3113883)

“…A pond habitat represents an area with a small body of water, at least 100 m in diameter. …”

Table_1_Farm-related determinants of food insecurity among livestock dependent households in two agrarian districts with varying rainfall patterns in Ghana.DOCX by Francis Sena Nuvey (6458915)

“…Household's odds of severe food insecurity decreased with each additional head of cattle in their herds (aOR = 0.97, 95% CI: 0.96, 0.99). …”

Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis by Oonagh E. Keag (4789215)

“…Pregnancy following cesarean delivery was associated with increased risk of placenta previa (OR 1.74, 1.62 to 1.87; <i>n</i> = 7,101,692; 10 studies), placenta accreta (OR 2.95, 1.32 to 6.60; <i>n</i> = 705,108; 3 studies), and placental abruption (OR 1.38, 1.27 to 1.49; <i>n</i> = 5,667,160; 6 studies).</p><p>This is a comprehensive review adhering to a registered protocol, and guidelines for the Meta-analysis of Observational Studies in Epidemiology were followed, but it is based on predominantly observational data, and in some meta-analyses, between-study heterogeneity is high; therefore, causation cannot be inferred and the results should be interpreted with caution.…”

Image_2_An Analysis Based on Japonica Rice Root Characteristics and Crop Growth Under the Interaction of Irrigation and Nitrogen Methods.png by Zhuoqian Wang (9012881)

“…From full heading to maturity stages, N2 could promote root growth, LAD, and CGR under AWD to a greater extent than those under the other treatments. …”

Image_2_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.JPEG by Veronika Marek (6725135)

“…In modern highly illuminated world, complaints about greater photosensitivity to blue light increasingly appear. …”

Aryl-Fluoride Reductive Elimination from Pd(II):  Feasibility Assessment from Theory and Experiment by Dmitry V. Yandulov (2507068)

“…Three-coordinate T-shaped geometry of Pd^IIAr(F)L (L = NHC, PR₃) was shown to offer kinetics and thermodynamics of Ar−F elimination largely compatible with synthetic applications, whereas coordination of strong fourth ligands to Pd or association of hydrogen bond donors with F each caused pronounced stabilization of Pd(II) reactant and increased activation barrier beyond the practical range. Decreasing donor ability of L promotes elimination kinetics via increasing driving force and <i>para</i>-substituents on Ar exert a sizable S_NAr-type TS effect. …”

Peripheral Blood T Cell Dynamics Predict Relapse in Multiple Sclerosis Patients on Fingolimod by Zi-Ye Song (731226)

“…The IL17-, IL9-, and IL4-producing CD4⁺T cell percentages were significantly higher at pre-treatment in MS patients compared with HCs (<i>p</i><0.01 for all), while the IL17-producing CD4⁺T cell percentages tended to show a transient increase at 2 weeks of fingolimod therapy (<i>p^corr</i>=0.0834).…”

Antagonism of mGluR5 or Erk signaling reduces induction of epileptiform activity in TSC2^+/− CA3 hippocampus. by Wyatt B. Potter (367463)

“…<p>(a) Representative traces of WT and TSC2^+/− slices following DHPG treatment (50 µM, 30 min) and in the presence and absence of drug. …”

Image_1_An Analysis Based on Japonica Rice Root Characteristics and Crop Growth Under the Interaction of Irrigation and Nitrogen Methods.jpg by Zhuoqian Wang (9012881)

“…From full heading to maturity stages, N2 could promote root growth, LAD, and CGR under AWD to a greater extent than those under the other treatments. …”

Image_2_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.JPEG by Veronika Marek (6725135)

“…In modern highly illuminated world, complaints about greater photosensitivity to blue light increasingly appear. …”

Image_3_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…In modern highly illuminated world, complaints about greater photosensitivity to blue light increasingly appear. …”

Image_5_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…In modern highly illuminated world, complaints about greater photosensitivity to blue light increasingly appear. …”

Image_7_Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.TIF by Veronika Marek (6725135)

“…In modern highly illuminated world, complaints about greater photosensitivity to blue light increasingly appear. …”