Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate by Sophia T. Mundle (303078)

“…The endonucleolytic activity of human apurinic/apyrimidinic endonuclease (AP endo) is a major factor in the maintenance of the integrity of the human genome. …”

Covid-19 and the impacts on mental health: a sample from Rio Grande do Sul, Brazil by Michael de Quadros Duarte (10399891)

“…<p></p><p>Abstract Pandemics such as that of COVID-19 affect a relatively large number of people and impose new rules and social habits on the world population. …”

Branching behavior of a N = 10 units network at trial T (case of weak inhibition = 0.55). by Elif Köksal-Ersöz (20378631)

“…When the punishment is weak, the system activates Br-1 in 0.26% the trials. This ratio decreases to 1% for a medium punishment and to 0 strong punishment. …”

Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate by Sophia T. Mundle (303078)

“…The endonucleolytic activity of human apurinic/apyrimidinic endonuclease (AP endo) is a major factor in the maintenance of the integrity of the human genome. …”

Mifepristone Promotes Adiponectin Production and Improves Insulin Sensitivity in a Mouse Model of Diet-Induced-Obesity by Takeshi Hashimoto (69561)

“…First, we explored the effects of mifepristone, on metabolic functions in obese mice receiving a high-fat diet. When these mice were fed mifepristone, they exhibited a marked improvement in insulin sensitivity, attenuated hepatic injury, and decreased adipocyte size, compared with mice that received only the high-fat diet. …”

Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate by Sophia T. Mundle (303078)

“…The endonucleolytic activity of human apurinic/apyrimidinic endonuclease (AP endo) is a major factor in the maintenance of the integrity of the human genome. …”

Phosphorus dynamics in a highly polluted urban drainage channel-shallow reservoir system in the Brazilian semiarid by GERMÁRIO M. ARAÚJO (7290242)

“…During the rainy season, as a consequence of dilution, phosphorus concentrations decreased by about 5-fold. …”

Changes in corticospinal excitability and the direction of evoked movements during motor preparation: A TMS study-5 by Gijs van Elswijk (90758)

“…For the APB, there was a significant effect of the precued direction at -100 ms and 250 ms (see Table 1). …”

The expression of miR-99a and mTOR in heart with hypertrophy and failure induced by TAC in mice. by Qiaoling Li (290816)

“…<p>A. Representative images of hearts. B-D. UCG measurement after TAC surgery. …”

A review on fermented aquatic food storage quality based on heat treatment and water retention technology by Lawal Adedoyin ISOLA (12729273)

“…Most of the end product quality of wine and meat, including taste, texture, and nutritional content, is determined by the main and secondary microbial metabolism formed during fermentation. A standard procedure in the food industry is the addition of salt to thermally processed meat and fish products in order to avoid weight loss that may otherwise have occurred due to the decreased water retaining capability caused by heat treatment. …”

Grx1 silencing causes MMP loss which can be prevented by thiol antioxidants and cyclosporine A. by Uzma Saeed (49670)

“…<p>SH-SY5Y cells were transfected with empty vector or shRNA to Grx1 and were used for quantitation of Grx1 at mRNA and protein levels and for the qualitative observation of MMP loss, 72 hr after the transfection. (A) Immunocytochemistry for Grx1 in cells transfected with shRNA to Grx1 show decreased Grx1 levels as compared to the mock control. …”

Decomposition and nutrients release from crop residues placed on a Yellow Latosol in the savanna of the Maranhão State by Luiz Fernando Carvalho Leite (10378353)

“…<p></p><p>Abstract In the no-tillage system the use of cover crops is a widely adopted alternative to increase the sustainability of the agricultural system. …”

MicroRNA differential expression versus LSR change of targets and preference of target sites in aUTRs. by Hao-Han Liaw (380928)

“…Target genes of up-regulated microRNAs (red) show a significantly decreased LSR in MCF-7 versus the down-regulated ones (green). …”

Oligomeric state of D4 and His-D4/A20_1–50. by Céline Contesto-Richefeu (531761)

“…The molecular mass of 43±2 kDa at the maximum peak height decreases down to ∼28 kDa suggesting that a monomer/dimer equilibrium of D4 (calculated molecular mass of 25.4 kDa) exists in solution (grey dashed line). …”

Transcranial Direct Current Stimulation (tDCS) modulates motor execution in a limb reaching task. by Thomas Zandonai (12813623)

“…Result indicates that individuals after receiving anodal stimulation decreased their movement time and increased their movement speed while the opposite happened after receiving a cathodal stimulation. …”

A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci by Martin A. Bewley (150467)

“…Inhibition of cathepsin D had no effect on early bacterial killing but inhibited the late phase of apoptosis-associated killing of pneumococci <em>in vitro</em>. Mice bearing a cathepsin D^−/− hematopoietic system demonstrated reduced macrophage apoptosis <em>in vivo</em>, with decreased clearance of pneumococci and enhanced recruitment of neutrophils to control pulmonary infection. …”

A patient with bilateral DME and massive hard exudates receiving different treatment strategies in both eyes. by Hsuan-Chieh Lin (9192861)

“…<p>(a) A 63-year-old female with hypertension and type 2 diabetes mellitus for 20 years presented with bilateral diabetic macular edema with massive hard exudates, unresponsive to intravitreal bevacizumab injection and macular photocoagulation. …”

Di/Tripeptide Uptake Is Enhanced by a Positive Feedback Loop Governed by the N-End Rule Pathway by Oliver R Homann (274920)

“…[<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0010080#pgen-0010080-b033" target="_blank">33</a>], with the authors' permission.…”

Brazilian International Development Cooperation and Public Opinion: Domestic Costs Faced by a Troubled Emerging Donor by Matheus Soldi Hardt (10359684)

“…Although the country does not see itself as a traditional donor, its IDC policy, in the context of South-South Cooperation, has increased the country’s international profile as an influential actor in the IDC landscape. …”

A Universal Trend of Reduced mRNA Stability near the Translation-Initiation Site in Prokaryotes and Eukaryotes by Wanjun Gu (123093)

“…Yet the most GC rich genes in these organisms do show such a signal. We conclude that reduced stability of the mRNA secondary structure near the start codon is a universal feature of all cellular life. …”