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greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
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7901
The effect of eEF1A mutations on TBSV repRNA accumulation in yeast.
Published 2010“…(C) Critical eEF1A residues for tombusvirus replication. Three novel mutants of eEF1A were identified, which exhibited increased tombusvirus replication (V301D, L374V/N377K, and F413L; yellow balls) while the new A76V and the previously identified T22S exhibited decreased tombusvirus replication (green balls). …”
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7902
Zinc exposure attenuates NR2A clusters and currents.
Published 2012“…(B) and (C) show the quantification data of (A). Both the number and mean intensity of NR2A clusters significantly decreased after zinc treatment. …”
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7903
Table 1_Tissue-specific effects of bacterial PncA overexpression on NAD+ metabolism and aging in mice: implications for tissue-specific aging interventions.docx
Published 2025“…Overexpressing the bacterial nicotinamidase PncA in mice increased NAD<sup>+</sup> levels in the liver and kidneys but decreased levels in the heart and hippocampus. …”
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7904
Table 1_Epidemiology and genetic characteristics of coxsackievirus A16 associated with hand-foot-mouth disease in Hangzhou city, Zhejiang province from 2021 to 2024.docx
Published 2025“…The detected number of CV-A16 began to rise in March, peaked in May–August, and then decreased in September. …”
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7905
Retinol and mineral status in grazing foals during the dry season
Published 2022“…Beta-carotene in grass showed a downward trend over time from 38.53 to 0.09 mg/kg of dry matter. …”
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7906
Data Sheet 1_Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis.pdf
Published 2025“…In vitro, experiments showed that semaglutide decreased the expression of S100A9 by activating the Protein Kinase C(PKC) pathway, thus inhibiting ferroptosis in cardiomyocytes.…”
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7907
Data Sheet 2_Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis.docx
Published 2025“…In vitro, experiments showed that semaglutide decreased the expression of S100A9 by activating the Protein Kinase C(PKC) pathway, thus inhibiting ferroptosis in cardiomyocytes.…”
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7908
Table 1_Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis.docx
Published 2025“…In vitro, experiments showed that semaglutide decreased the expression of S100A9 by activating the Protein Kinase C(PKC) pathway, thus inhibiting ferroptosis in cardiomyocytes.…”
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7909
Image 1_Epidemiology and genetic characteristics of coxsackievirus A16 associated with hand-foot-mouth disease in Hangzhou city, Zhejiang province from 2021 to 2024.jpeg
Published 2025“…The detected number of CV-A16 began to rise in March, peaked in May–August, and then decreased in September. …”
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7910
Supplementary Material for: The Designer Antimicrobial Peptide A-hBD-2 Facilitates Skin Wound Healing by Stimulating Keratinocyte Migration and Proliferation
Published 2018“…<b><i>Conclusion:</i></b> Our data suggest that A-hBD-2 may be a promising candidate therapy for wound healing.…”
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7911
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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7912
Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo)
Published 2014“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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7913
A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in <em>Leishmania donovani</em>
Published 2012“…<div><p>Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (<em>N</em><sup>€</sup>-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, <em>Leishmania donovani,</em> which causes visceral leishmaniasis. …”
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7914
Efmoroctocog Alfa: A Review in Haemophilia A
Published 2021“…</p> <p><b> </b></p> <p><b>Authorship and Conflict of interest</b> James E. Frampton is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. …”
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7915
Chemoresistance of Human Monocyte-Derived Dendritic Cells Is Regulated by IL-17A
Published 2013“…Immature dendritic cells were CD40<sup>low</sup>HLADR<sup>low</sup> CD1a<sup>+</sup> MCL1<sup>+</sup>, did not express CD14, CD68 or BCL2A1, and displayed a short 2-day lifespan. …”
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7916
Porcine Coro1A inhibit <i>H.parasuis</i> induced NF-κB activation.
Published 2014“…<p>(A) PK-15 cells were transfected with pNF-κB-luc (0.2 µg) and pRL-TK (0.05 µg), then cells were control-inoculated, live or heat-killed <i>H.parasuis</i> (10<sup>7</sup> CFU) inoculated. …”
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7917
Reduction of NF-κB activation when porcine Coro1A was overexpressed.
Published 2014“…<p>(A) PK-15 cells were co-transfected with the pNF-κB-luc reporter plasmid (0.2 µg), pRL-TK plasmid (0.05 µg), along with 0.6 µg of the expression plasmid encoding porcine Coro1A protein. …”
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7918
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7919
HilD-activation results in a growth defect.
Published 2023“…Representative images are shown in the right panel. the same strains as in (A) were analysed. (C) Time-lapse microscopy analysis reveals a decreased cell elongation rate (left), a decrease in the maximal cell length (middle) as well as decreased length elongation during a division cycle (right) upon HilD induction. …”
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7920