Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol by Yuhuan Li (337260)

“…The inhibition and knockout of transporters, such as P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and multidrug resistance-associated proteins (MRPs), exhibited a marked increase in subcellular kaempferol and decrease in its subcellular glucuronides. …”

Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol by Yuhuan Li (337260)

“…The inhibition and knockout of transporters, such as P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and multidrug resistance-associated proteins (MRPs), exhibited a marked increase in subcellular kaempferol and decrease in its subcellular glucuronides. …”

Interplay of Efflux Transporters with Glucuronidation and Its Impact on Subcellular Aglycone and Glucuronide Disposition: A Case Study with Kaempferol by Yuhuan Li (337260)

“…The inhibition and knockout of transporters, such as P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and multidrug resistance-associated proteins (MRPs), exhibited a marked increase in subcellular kaempferol and decrease in its subcellular glucuronides. …”

Map of studied gentoo penguin colony locations along a latitudinal gradient ranging from 1) Maiviken, South Georgia to 2) Georges Point, 3) Port Lockroy, and 4) Petermann Island on... by Caitlin Black (2141434)

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for institutional births in a census of 379 clinics providing services in Liberia fro... by Bradley H. Wagenaar (311527)

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for measles vaccinations in a census of 379 clinics providing services in Liberia fro... by Bradley H. Wagenaar (311527)

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for clinic visits in a census of 379 clinics providing services in Liberia from 2010–... by Bradley H. Wagenaar (311527)

Participants with virologic suppression or failure at week 24. by Tosi M. Mwakyandile (16408705)

Socio-demographic and clinical characteristics of HIV-infected treatment-naïve individuals initiating ART. by Tosi M. Mwakyandile (16408705)

Consolidated Standards of Reporting Trials flow diagram for participants in the trial. by Tosi M. Mwakyandile (16408705)

BPAG1a and b Associate with EB1 and EB3 and Modulate Vesicular Transport, Golgi Apparatus Structure, and Cell Migration in C2.7 Myoblasts by Kseniia Poliakova (632665)

“…Finally, knockdown of BPAG1a/b caused a specific decrease in the directness of cell migration, but did not impair initial cell adhesion. …”

Most frequently experienced adverse events among study participants by treatment arms from baseline through week 24. by Tosi M. Mwakyandile (16408705)

Qualitative summary of trends observed in this study, relating catchment size and viral prevalence to (a) the extent to which near-source wastewater surveillance revealed locally-s... by Jay C. Bullen (10232606)

Cumulative incidence of mortality and loss to follow-up (LTF) among study participants by treatment arms from baseline through week 24. by Tosi M. Mwakyandile (16408705)

Cumulative incidence of morbidity, loss to follow-up (LTF) and mortality among study participants by treatment arms from baseline through week 24. by Tosi M. Mwakyandile (16408705)

Median changes in CD4 count, platelet activation, immune activation, and exhaustion markers from baseline through week 12 and week 24. by Tosi M. Mwakyandile (16408705)

Illustrative MRI of a given patient at baseline and at the end of follow-up. by Lucas L. A. Nunes (19360381)

CFDP1 and H2A.Z co-bound peaks. by Gokul Gopinathan (7930679)

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Modulation of serum lipid levels after a single-dose treatment of MGL-3196 or T3 in HFD fed rats. by Xuan G. Luong (9761423)

Subjects:

EA inhibited the DNMT3a overecpression and restore MOR expression in the CCI rats DRG. by Feng Wang (44414)

Subjects: