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greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
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224201
Data Sheet 2_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind...
Published 2025“…</p>Methods<p>In this study, the chronic unpredictable mild stress (CUMS) method was used to establish a rat model of depression to investigate the ameliorative effects of HLTP on depression.…”
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224202
Schematic summary: MC immuno-phenotype and MC-CD8+ T-cell interactions in healthy compared to lesional AA skin.
Published 2014“…Most of them express IL-10, TGFβ1 while only some express OX40L and PD-L1 and very few express CD30L and ICAM-1 (A). In lesional AA skin, the degranulation of MCs is increased (release of tryptase, heparin and histamine) and the expression of tryptase is increased, while the contents of TGFbeta1, IL-10 are decreased. …”
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224203
Table_2_Associations between plasma metal elements and risk of cognitive impairment among Chinese older adults.DOCX
Published 2024“…Moreover, subgroup analyses by age, sex, and body mass index suggested a consistent significant correlation (p < 0.05).…”
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224204
Image_1_Comprehensive Analysis of Long Non-coding RNA Modulates Axillary Bud Development in Tobacco (Nicotiana tabacum L.).JPEG
Published 2022“…By lncRNA transcriptomes of axillary buds in topped and untopped tobacco plants, we identified a total of 13,694 lncRNAs. LncRNA analysis indicated that the promoted growth of axillary bud by topping might be partially ascribed to the genes related to hormone signal transduction and glycometabolism, trans-regulated by differentially expressed lncRNAs, such as MSTRG.52498.1, MSTRG.60026.1, MSTRG.17770.1, and MSTRG.32431.1. …”
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224205
Temporal and spatial variation of potassium balance in agricultural land at national and regional levels in China
Published 2017“…<div><p>Linking potassium (K) balance to soil fertility creates a valuable indicator for sustainability assessment in agricultural land-use systems. …”
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224206
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224207
Recombinant PLTP induced FLS proliferation and cytokine production independently of its lipid transfer ability.
Published 2018“…<p><b>(A)</b> RA-FLS were stimulated for 48 hours with 2μg/ml of PLTP or heat inactivated-PLTP (heated-PLTP) and proliferation was evaluated using [<sup>3</sup>H] thymidine incorporation during the last day of stimulation. …”
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224208
Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts
Published 2024“…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …”
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224209
Image_1_Geographic Variation in the Petiole–Lamina Relationship of 325 Eastern Qinghai–Tibetan Woody Species: Analysis in Three Dimensions.pdf
Published 2021“…Understanding environmental gradients in the relationship and its underlying mechanisms remains a critical challenge for ecologists. We investigated the possible scaling of the petiole–lamina relationships in three dimensions, i.e., petiole length (PL) vs. lamina length (LL), petiole cross sectional area (PCA) vs. lamina area (LA), and petiole mass (PM) vs. lamina mass (LM), for 325 Qinghai–Tibetan woody species, and examined their relation to leaf form, altitude, climate, and vegetation types. …”
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224210
Effect of SILD on STZ-diabetic kidney: modulation of macrophage infiltration.
Published 2015“…<p>(A) Representative photomicrographs of H&E-stained kidneys (×200 magnification) on harvesting show normal structure in the CTRL and SILD, mild mesangial expansion and tubular damage in the STZ, and normal structure in the STZ+SILD group (bar represents 100 μm).…”
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224211
DataSheet1_Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway.XLSX
Published 2021“…The combination of network pharmacology approaches with experimental validation may offer a useful tool to characterize the molecular mechanism of multicomponent complexes.…”
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224212
Table1_HSP90 Inhibitor 17-AAG Attenuates Nucleus Pulposus Inflammation and Catabolism Induced by M1-Polarized Macrophages.DOCX
Published 2022“…In conclusion, HSP90 inhibitor 17-AAG attenuates NP inflammation and catabolism induced by M1 macrophages, suggesting 17-AAG as a promising candidate for IVDD treatment.</p>…”
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224213
MCT4/CD147 transporter complex-associated cell proliferation, migration and invasion in U87 and U251 cell lines.
Published 2024“…<p><b>A.</b> Cell proliferation curves of U251 cells. …”
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224214
Table2_Deciphering the mechanism of PSORI-CM02 in suppressing keratinocyte proliferation through the mTOR/HK2/glycolysis axis.XLSX
Published 2023“…<p>Hyperplasia of epidermal keratinocytes that depend on glycolysis is a new hallmark of psoriasis pathogenesis. Our previous studies demonstrated that PSORI-CM02 could halt the pathological progression of psoriasis by targeting inflammatory response and angiogenesis, but its effect(s) and mechanism(s) on proliferating keratinocytes remained unclear. …”
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224215
Spanish real-world experience with fingolimod in relapsing-remitting multiple sclerosis patients: MS NEXT study
Published 2020“…</p><p>Methods</p><p>This observational, retrospective, multicentre, nationwide study was performed at 56 Spanish hospitals and involved 804 RRMS patients who received oral fingolimod (0.5 mg) since November 2011, with a minimum follow-up of 12 months.</p><p>Results</p><p>The mean annualized relapse rate (ARR) in the year before fingolimod was 1.08 and the median EDSS was 3; patients were exposed to fingolimod for 2.2 years as average; regarding magnetic resonance imaging (MRI) activity, more than half of the patients had >20 lesions at baseline. …”
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224216
Table_3_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx
Published 2022“…Notably, 5 optimal ASV-based microbial markers were identified as the diagnostic model of AL amyloidosis and the AUC value of the train set and the test set was 0.8549 (95% CI 0.7310-0.9789) and 0.8025 (95% CI 0.5771-1), respectively. With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”
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224217
Image_1_Precision immunointerception of EGFR-driven tumorigenesis for lung cancer prevention.jpeg
Published 2023“…In this study, we identified immunogenic epitopes for the common EGFR mutations in humans and formulated a multi-peptide vaccine (E<sup>mut</sup> Vax) targeting the EGFR L858R, T790M, and Del19 mutations. …”
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224218
Image_5_Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.tif
Published 2023“…However, higher IL37 expression correlated with a reduced proinflammatory cytokine response in murine colonic organoids. …”
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224219
Investigation on the morphological and optical evolution of bimetallic Pd-Ag nanoparticles on sapphire (0001) by the systematic control of composition, annealing temperature and ti...
Published 2017“…Depending on the annealing temperature, Pd-Ag alloy nanostructures evolve with a series of configurations, i.e. nucleation of voids, porous network, elongated nanoclusters and round alloy NPs. …”
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224220
Data_Sheet_2_RETRACTED: Endothelial-Monocyte Activating Polypeptide II Suppresses the In Vitro Glioblastoma-Induced Angiogenesis by Inducing Autophagy.DOC
Published 2024“…<p>The obstacle in delivering therapeutics to glioblastoma (GBM) is tumor-induced angiogenesis which leads to the formation of abnormal vessels and a dysfunctional blood-tumor barrier. Here, we elucidated the effect of endothelial-monocyte activating polypeptide II (EMAP II) on the GBM-induced angiogenesis as well as its potential mechanisms. …”