Effect of Vankyrins on immune gene expression. by Gwenaelle Gueguen (451908)

“…<p><b>A</b>. Both Vankyrins strongly reduce the expression of <i>Drosomycin</i> in manually-poked larvae (t = 4.1, df = 6, p = 0.006 for <i>Cg>GFP, P1</i> and t = 4, df = 5, p = 0.009 for <i>Cg>GFP, I3</i>). …”

Refractoriness of <i>Sergentomyia schwetzi</i> to <i>Leishmania</i> spp. is mediated by the peritrophic matrix by Jovana Sadlova (48915)

“…Here we tested the hypothesis that in <i>Sergentomyia schwetzi</i> the PM creates a physical barrier that prevents escape of <i>Leishmania</i> parasites from the endoperitrophic space.…”

Table_2_Disparate Interferon Signaling and Shared Aberrant Basaloid Cells in Single-Cell Profiling of Idiopathic Pulmonary Fibrosis and Systemic Sclerosis-Associated Interstitial L... by Eleanor Valenzi (8508294)

“…Alveolar type I cells were dramatically decreased in both IPF and SSc-ILD, with a distinct transcriptome signature separating these cells by disease. …”

Table 7_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx by Yanyao Lu (22163632)

“…However, the specific effects of different drainage durations on soil microorganisms and metabolites remain unclear. This study adopted a multi-omics research method. After nontargeted metabolomics analysis of lipids as the main metabolite, microbial diversity analysis and lipidomics analysis were conducted to determine the main influencing factors. …”

Identification of key genes involved in the recurrence of glioblastoma multiforme using weighted gene co-expression network analysis and differential expression analysis by Peng Ren (337555)

“…Among these, 13 genes – <i>EHF, TRPM1, FXYD4, CDH15, LHX5, TP73, FBN3, TLX1, C1QL4, COL2A, SEC61G, NEUROD4</i> and <i>GPR139</i> – were differentially expressed in recurrent GBM samples; low <i>LHX5</i> and <i>TLX1</i> expression predicted poor outcomes. …”

Image3_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.TIF by Haomiao Li (2743693)

“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”

Long-term acceptance of MHC mismatched cardiac allograft in Nur77Tg recipients. by Ran Tao (81449)

“…<p>(a) BALB/c cardiac allografts were accepted long-term by Nur77Tg recipients, in contrast to acute rejection in WT C57BL/6 recipients (p<0.001). …”

<i>S. boulardii</i> Fails to Hold Its Cell Wall Integrity against Nonpathogenic <i>E. coli</i>: Are Probiotic Yeasts Losing the Battle? by Satyajit Lenka (10290092)

“…Co-cultured methylene blue-supplemented agar-plate assay indicates that rough lipopolysaccharides might be playing a key role in <i>S. boulardii</i> cell wall damage. …”

Table_11_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx by Jipeng Yan (8473710)

“…Notably, 5 optimal ASV-based microbial markers were identified as the diagnostic model of AL amyloidosis and the AUC value of the train set and the test set was 0.8549 (95% CI 0.7310-0.9789) and 0.8025 (95% CI 0.5771-1), respectively. With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”

Image 5_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Image_3_Systemic Oxidative Stress, Aging and the Risk of Cardiovascular Events in the General Female Population.TIFF by Martin F. Bourgonje (10115305)

“…<p>Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free thiols (R-SH, sulfhydryl groups), which are key components of the extracellular antioxidant machinery. …”

Table3_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.XLSX by Yan Zhou (6523)

“…Among the many biomarkers predicting the efficacy of NAC, immune-related biomarkers, such as immune-related genes and tumor-infiltrating lymphocytes (TILs), play a key role.</p><p>Methods: We analyzed gene expression from several datasets in the Gene Expression Omnibus (GEO) database and evaluated the relative proportion of immune cells using the CIBERSORT method. …”

Mitochondrial Superoxide Signaling Contributes to Norepinephrine-Mediated T-Lymphocyte Cytokine Profiles by Adam J. Case (232046)

“…Overall, these studies indicate that mitochondrial metabolism and O₂^●--mediated redox signaling play a regulatory role in the T-lymphocyte response to NE.…”

Differential Roles of Fibroblast Growth Factor Receptors (FGFR) 1, 2 and 3 in the Regulation of S115 Breast Cancer Cell Growth by Kati M. Tarkkonen (119690)

“…The results also suggest that the expression of FGFR1 itself is regulated by FGF-8 and FGF signaling, which may be of importance in breast tumors expressing FGFs at a high level.</p> </div>…”

Image_2_Abnormal Glucose Metabolism in Male Mice Offspring Conceived by in vitro Fertilization and Frozen-Thawed Embryo Transfer.TIF by Ningxin Qin (10115329)

“…It is of great necessity to assess the safety of FET and investigate the long-term effect including glucose metabolism on FET-conceived offspring. The mouse model is a highly efficient method to figure out the relationship between the process of FET and offspring health. …”

Table_4_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.DOCX by Dong-sheng Di (11634688)

“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic by Fang Han (435237)

“…<div><p>Previous studies in narcolepsy, an autoimmune disorder affecting hypocretin (orexin) neurons and recently associated with H1N1 influenza, have demonstrated significant associations with five loci. Using a well-characterized Chinese cohort, we refined known associations in TRA@ and P2RY11-DNMT1 and identified new associations in the TCR beta (TRB@; rs9648789 max P = 3.7×10⁻⁹ OR 0.77), ZNF365 (rs10995245 max P = 1.2×10⁻¹¹ OR 1.23), and IL10RB-IFNAR1 loci (rs2252931 max P = 2.2×10⁻⁹ OR 0.75). …”

Longitudinal trends in the prevalence of hyperuricaemia and chronic kidney disease in hypertensive and normotensive adults by Alena Krajčoviechová (8822516)

“…A decline in the prevalence of CKD was only observed in hypertensive individuals and was accompanied by the increased use of RAS inhibitors and CCBs.…”

DataSheet1_Regulation of hydrogen rich water on strawberry seedlings and root endophytic bacteria under salt stress.docx by Renyuan Wang (10921218)

“…Our findings indicate that HRW could help restore the microecological homeostasis of strawberry seedlings, thus further mitigating salt stress. This study provides a novel perspective on the mechanisms by which HRW alleviates salt stress, thereby enriching the scientific understanding of hydrogen’s applications in agriculture.…”

Image 2_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”