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greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
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224701
Glucocorticoid and dietary effects on mucosal microbiota in canine inflammatory bowel disease
Published 2019“…Apicaljunction protein (AJP) expression using immunohistochemistry investigated the effect of medical therapy on intestinal barrier integrity. All IBD dogs had a reduction in GI signs following diet and prednisone therapy compared with baseline CIBDAI scores (<i>P</i> < 0.05). …”
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224702
Image2_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.TIF
Published 2022“…Among the many biomarkers predicting the efficacy of NAC, immune-related biomarkers, such as immune-related genes and tumor-infiltrating lymphocytes (TILs), play a key role.</p><p>Methods: We analyzed gene expression from several datasets in the Gene Expression Omnibus (GEO) database and evaluated the relative proportion of immune cells using the CIBERSORT method. …”
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224703
DataSheet_6_Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction...
Published 2021“…We confirmed this mechanistic effect in a CLP-induced sepsis model of intestinal SIRT3 conditional-knockout mice, and found that melatonin preserved mitochondrial function and induced autophagy of small-intestine epithelial cells; these effects were dependent on SIRT3 activation. …”
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224704
ESI–MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell Xenografts
Published 2015“…However, recent evidence has demonstrated the promise of bone marrow-derived mesenchymal stem cells (BM-hMSCs) as a therapeutic delivery vehicle for anti-glioma agents due to their ability to migrate or home to human gliomas. …”
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224705
DataSheet1_Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies.pdf
Published 2022“…Overexpression of zDHHC5 in rabbit ventricular cardiomyocytes did not alter palmitoylation of its substrates or overall cardiomyocyte contractility, suggesting changes in zDHHC5 expression in disease may not be a primary driver of pathology. zDHHC5 itself is regulated by post-translational modifications, including palmitoylation in its C-terminal tail. …”
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224706
Table 2_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.docx
Published 2025“…<p>The mining industry in China plays a pivotal role in economic development but also leads to severe environmental issues, particularly heavy metal pollution in soils. …”
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224707
Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage
Published 2023“…Ferroptosis, a form of regulatory non-apoptotic cell death driven by iron-dependent lipid peroxidation, accounts for more than 80% of the total types of neuronal death in the acute phase of intracerebral hemorrhage (ICH). …”
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224708
Image_4_Synergistic and Antagonistic Effects of Biogenic Silver Nanoparticles in Combination With Antibiotics Against Some Pathogenic Microbes.jpg
Published 2021“…The synergistic effects of biogenic AgNPs in combination with some antibiotics support their potential as a safe therapeutic for bacterial infections because they are capped with organic biomolecules.…”
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224709
Image_1_Carbon Amendments Influence Composition and Functional Capacities of Indigenous Soil Microbiomes.tif
Published 2020“…Mesocosms were established with soil from two field sites varying in soil organic matter content (low organic matter, LOM; high organic matter, HOM), that were amended at intervals over nine months with low or high dose solutions of glucose, fructose, malic acid, a mixture of these compounds, or water only (non-amended control). …”
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224710
Image2_Treadmill training does not enhance skeletal muscle recovery following disuse atrophy in older male mice.pdf
Published 2023“…<p>Introduction: A hallmark of aging is poor muscle recovery following disuse atrophy. …”
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224711
Effects of Dp on mitochondrial dysfunction in oxLDL-induced HUVECs.
Published 2013“…<p>HUVECs were pretreated with various Dp concentrations (1, 10, 50 and 100 μM, respectively) for 2 h, and then exposed to 100 μg/mL of oxLDL for another 24 h. (A) Intracellular ROS levels were estimated using the probe DCFH-DA. …”
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224712
DataSheet4_Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway.XLSX
Published 2021“…The combination of network pharmacology approaches with experimental validation may offer a useful tool to characterize the molecular mechanism of multicomponent complexes.…”
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224713
Table_2_Microbial community diversity of an integrated constructed wetland used for treatment of sewage.XLSX
Published 2024“…<p>The microbial community diversity in Constructed Wetland System (CWS) plays a key role in the removal of pollutants from waste water. …”
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224714
Table_1_Change of mortality of patients with acute ischemic stroke before and after 2015.docx
Published 2022“…</p>Materials and methods<p>A retrospective cohort study was conducted using combined anonymized data from the Acute Stroke Assessment Registry of Korea and the Health Insurance Review & Assessment Service database. …”
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224715
Image_3_Splenic SUMO1 controls systemic inflammation in experimental sepsis.jpeg
Published 2023“…In the spleen, endotoxemia induced a distinct temporal and substrate specificity for SUMO1 and SUMO2/3, and both were inhibited by TAK981. …”
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224716
Table_1_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.xlsx
Published 2022“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”
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224717
Data_Sheet_3_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP
Published 2022“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”
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224718
Administration of rIL-22 reduces AHR and airway inflammation.
Published 2013“…<p>Airway responsiveness (panel A), cell counts in BAL fluid (panel B) and lung tissue inflammation and goblet cell metaplasia (panel C) were assessed in mice 48 h after the last airway challenge. …”
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224719
Table2_Geochemistry of Formation Water and Its Implications for Petroleum Source Rocks in the Fengcheng Formation, Mahu Depression, Xinjiang, China.xlsx
Published 2022“…From the first member to the third member of the formation, the salinity first increases and then decreases. This low-high-low trend corresponds to the initial stage of alkaline lake development followed by strong alkali formation and a final stage of water retreat. …”
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224720
Table_1_Direct Comparison of Herbicidal or Biological Treatment on Myriophyllum spicatum Control and Biochemistry.docx
Published 2018“…Several treatment alternatives are available for milfoil control, although cost and efficacy vary significantly, with some treatments resulting in more harm to the native population than no treatment at all. A series of field-based microcosms containing actively growing milfoil were constructed in order to directly compare the impact of two herbicides (2,4-dichlorophenoxyacetic acid and fluridone) and the milfoil weevil (Euhrychiopsis lecontei) on weed control and plant biochemistry. …”