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greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
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26201
Image_1_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png
Published 2023“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”
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26202
HIV-Tat regulates macrophage gene expression in the context of neuroAIDS
Published 2017“…We found that HIV Tat increased expression of C5, APBA1, and BDNF, and decreased CRLF2. The K50A Tat-mutation dysregulated expression of these genes without affecting the binding of the Tat complex to their gene sequences. …”
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26203
Image_2_Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.jpeg
Published 2021“…In mice having B-cell-specific Rap1a/b double knockouts (DKO), the number of B cells in lymph nodes decreased to approximately 4% of that of control mice, and B cells were present in the spleen and blood. …”
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26204
Lysine Mutation of the Claw-Arm-Like Loop Accelerates Catalysis by Cellobiohydrolases
Published 2019“…Searching for viable strategies to accelerate the catalytic cycle of glycoside hydrolase family 7 (GH7) cellobiohydrolase I (CBHI)the workhorse cellulose-degrading enzymes, we have performed a total of 12-μs molecular dynamics simulations on GH7 CBHI, which brought to light a new mechanism for cellobiose expulsion, coined “claw-arm” action. …”
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26205
Image_1_Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.jpg
Published 2021“…In mice having B-cell-specific Rap1a/b double knockouts (DKO), the number of B cells in lymph nodes decreased to approximately 4% of that of control mice, and B cells were present in the spleen and blood. …”
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26206
Image_8_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png
Published 2023“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”
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26207
Table_1_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.docx
Published 2023“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”
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26208
DataSheet_1_Complement C3 and Activated Fragment C3a Are Involved in Complement Activation and Anti-Bacterial Immunity.pdf
Published 2022“…<p>In the complement system, C3 is a central component in complement activation, immune defense and immune regulation. …”
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26209
Image_4_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png
Published 2023“…These changes could partially be confirmed at functional level, with significant increases in apoptosis and decreases in lipid uptake and IL-6, IL-8, and TNFa cytokine secretion after STAT5A knockdown. …”
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26210
Data_Sheet_1_Physical and Physiological Match-Play Demands and Player Characteristics in Futsal: A Systematic Review.pdf
Published 2020“…<p>Futsal, also known as five-a-side indoor soccer, is a team-sport that is becoming increasingly popular. …”
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26211
Lysine 50 of Tat regulates expression of C5, CRLF2, APBA1, and BDNF genes.
Published 2017“…<p>THP-1Tat-Flag and THP-1Tat K50ATat-Flag cell lines (generated from independent experiments described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179882#pone.0179882.g005" target="_blank">Fig 5</a>) were differentiated to macrophages with PMA for 24 and 48 hours. …”
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26212
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
Published 2020“…ABCB1 is a promising therapeutic target for overcoming multidrug resistance (MDR). …”
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26213
DataSheet_1_Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis.pdf
Published 2022“…Objectives<p>HTR2A is previously identified as a susceptibility gene for rheumatoid arthritis (RA). …”
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26214
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
Published 2020“…ABCB1 is a promising therapeutic target for overcoming multidrug resistance (MDR). …”
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26215
DataSheet_1_METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner.docx
Published 2022“…<p>N<sup>6</sup>-metyladenosine (m<sup>6</sup>A) RNA methylation has been proven to be involved in diverse biological processes, but its potential roles in the development of lipopolysaccharide (LPS) induced retinal pigment epithelium (RPE) inflammation have not been revealed. …”
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26216
Table_1_Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis.xlsx
Published 2022“…Objectives<p>HTR2A is previously identified as a susceptibility gene for rheumatoid arthritis (RA). …”
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26217
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators
Published 2020“…ABCB1 is a promising therapeutic target for overcoming multidrug resistance (MDR). …”
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26218
Image_1_Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis.tif
Published 2022“…Objectives<p>HTR2A is previously identified as a susceptibility gene for rheumatoid arthritis (RA). …”
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26219
Data_Sheet_1_Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring.docx
Published 2020“…Infected kidneys from androgenized mice harbored more alternatively activated (M2) macrophages than vehicle-treated mice, reflecting an earlier shift from a pro-inflammatory (M1) phenotype. Androgen exposure also led to a sharp increase in activin A-producing myeloid cells in the infected kidney, as well as decreased levels of follistatin (which normally antagonizes activin action). …”
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26220
Table_1_An aldehyde dehydrogenase gene, GhALDH7B4_A06, positively regulates fiber strength in upland cotton (Gossypium hirsutum L.).xlsx
Published 2024“…Virus-induced gene silencing of GhALDH7B4 in cotton caused significant decreases in FS and fiber micronaire. Conversely, GhALDH7B4_A06<sup>O</sup> overexpression in Arabidopsis boosted cell wall component contents in the stem. …”