Meta-regression of macrolide resistance Mycobacterium isolates over the years; The results of the meta-regression analysis are presented in a scatter plot that shows the trend in t... by Saeid Sadeghi Ghazi Chaki (22582028)

“…The scatter plot reveals how resistance rates have changed over time. A fitted regression line indicates the overall trend, highlighting whether resistance rates have increased, decreased, or remained stable.…”

Demographic characteristics, laboratory features and complications in 346 cases of brucellosis: A retrospective study from Qatar by Varikkodan, Irfan

“…Objectives: To study the epidemiology and laboratory findings and outcomes of human brucellosis in the state of Qatar. Methods: A retrospective study involving adult patients with a definitive diagnosis of brucellosis was conducted. …”
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X-ray crystallography identified a functional glycan-binding pocket on the side of the light chain of 2526. by Matthew J. Vukovich (19697895)

“…<p>(A) Crystal structure of 2526 IgG1 Fab complexed with D-Mannose is shown. …”

Investigating the blood-host plasticity and dispersal of Anopheles coluzzii using a novel field-based methodology by Orsborne J.

“…Results: A collection strategy utilising a transect of mosquito traps placed at 50 m intervals allowed the collection of blood-fed Anopheles coluzzii from a malaria-endemic village of southern Ghana where human host availability ranged from zero (a cattle pen), increasing until humans were the dominant host choice (the middle of the village). …”
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data_sheet_1_A Comparative Study of Primary Adenoid Cystic and Mucoepidermoid Carcinoma of Lung.DOCX by Vivek Kumar (261698)

Image_1_Divergent Antiviral Mechanisms of Two Viperin Homeologs in a Recurrent Polyploid Fish.tiff by Cheng-Yan Mou (4269523)

“…Subsequently, using co-immunoprecipitation (Co-IP) screening analysis, both CgViperin-A and CgViperin-B were found to interact with crucian carp (C. auratus) herpesvirus (CaHV) open reading frame 46 right (ORF46R) protein, a negative herpesvirus regulator of host interferon (IFN) production, and to promote the proteasomal degradation of ORF46R via decreasing K63-linked ubiquitination. …”

Supplementary Material for: Hypofractionated Radiotherapy for Anaplastic Thyroid Carcinoma: 15 Years of Experience in a Single Institution by Takahashi N. (4478392)

“…<b><i>Background:</i></b> Anaplastic thyroid carcinoma (ATC) is a rare cancer and has a poor prognosis. Several radiation protocols have been reported, but the results were not satisfactory. …”

Image3_GSK-3 Inhibition Modulates Metalloproteases in a Model of Lung Inflammation and Fibrosis.JPEG by Francesco Cinetto (8638674)

“…To the same extent, GSK-3 inhibition blunted the increased MMP-9 and MMP-2 activity induced by pro-fibrotic stimuli in a human lung fibroblast cell line. Moreover, the αSMA protein level, a marker of fibroblast-to-myofibroblast transition involved in fibrosis, was decreased in primary fibroblasts treated with TGFβ following GSK-3 inhibition. …”

Image1_GSK-3 Inhibition Modulates Metalloproteases in a Model of Lung Inflammation and Fibrosis.JPEG by Francesco Cinetto (8638674)

“…To the same extent, GSK-3 inhibition blunted the increased MMP-9 and MMP-2 activity induced by pro-fibrotic stimuli in a human lung fibroblast cell line. Moreover, the αSMA protein level, a marker of fibroblast-to-myofibroblast transition involved in fibrosis, was decreased in primary fibroblasts treated with TGFβ following GSK-3 inhibition. …”

Predictors of nonfunctional arteriovenous access at hemodialysis initiation and timing of access creation: A registry-based study by Natalia Alencar de Pinho (3771187)

“…A higher percentage of AV access creation at the region level was associated with a lower rate of nonfunctional AV access (OR 0.98, 95% CI 0.98–0.99 per 1% increase). …”

Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx by Alexandra Prodea (22617710)

“…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …”

Table_3_Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis.DOCX by Qiang Lu (49688)

“…Patients with pre-existing meibomian gland dysfunction (MGD) had worsened subjective symptoms of dry eye (1.31, 95% confidence interval (CI) [0.66, 1.95], P < 0.0001), a reduced tear break-up time (BUT) (−2.27, 95% CI [−2.66, −1.88], P < 0.0001), and a worse corneal fluorescein staining (CFS) score (0.75, 95% CI [0.5, 1.0], P < 0.0001) after phacoemulsification cataract surgery, whereas in the general population, the subjective symptoms score and CFS remained unchanged and BUT decreased slightly after surgery. …”

Table_1_Achieving WHO's Goal for Reducing Cesarean Section Rate in a Chinese Hospital.DOCX by Yan-Jie Ji (11736254)

Data_Sheet_9_Predictors of sequence capture in a large-scale anchored phylogenomics project.csv by Renato Nunes (5704595)

“…Sequence capture, also known as anchored hybrid enrichment, is a method to produce reduced representation libraries for NGS sequencing. …”

Table 1_The impact of climate change on medicinal plants and natural products: A scoping review.pdf by Marce Inggritha Takubessi (22671905)

“…Background<p>Medicinal plants and natural products are essential for healthcare systems globally, and, at the same time, they are a part of ecosystems and have major socioeconomic importance in many regions of the world. …”

Publication trends of research on diabetes mellitus and T cells (1997–2016): A 20-year bibliometric study by Ye Gao (338234)

“…<div><p>Introduction</p><p>Diabetes Mellitus (DM) is a huge burden for human health. Recent studies show the close relationship between DM and T cells. …”

Image1_A Stable Chemokine Gradient Controls Directional Persistence of Migrating Dendritic Cells.tiff by Thomas Quast (249407)

“…In contrast to Dictyostelium amoeba, DCs are unable to decode oscillatory stimulation of soluble chemokine traveling waves into a directional response toward the wave source. …”

Table_4_A Multilevel Assessment of Plasticity in Response to High-Altitude Environment for Agama Lizards.pdf by Yin Qi (314969)

“…Both lizards were capable of acclimating to the high-altitude environment without sacrificing their performance in bite force, but they also showed high plasticity in tail display behavior by either decreasing the intensity of a specific display component (P. forsythii) or by the trade-off between display components (P. axillaris). …”

DataSheet_1_PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.zip by Sharmilee Vetrivel (10176326)

“…Background<p>We performed a transcriptomic analysis of adrenal signaling pathways in various forms of endogenous Cushing’s syndrome (CS) to define areas of dysregulated and druggable targets.…”

A novel crosstalk between BRCA1 and poly (ADP-ribose) polymerase 1 in breast cancer by Da Li (194457)

“…Here, we showed that: (i) BRCA1 inactivation events (mutation, promoter methylation, or knockdown) were accompanied by increased PARP1 and nicotinamide adenine dinucleotide (NAD) levels, and a subsequent increase in NAD-dependent PARP1 activity in MDA-MB-231 and primary breast cancer cells; (ii) the overexpression of BRCA1 resulted in decreased PARP1 and NAD levels, and a subsequent impairment in NAD-dependent PARP1 activity in MDA-MB-231 and primary breast cancer cells; and (iii) intracellular NAD levels were largely responsible for regulating PARP1 activity in breast cancer cells, and NAD levels were positively correlated with PARP1 activity in human breast cancer specimens (R = 0.647, <i>P</i> < 0.001). …”