The Proteasome Inhibitor Bortezomib Induces an Inhibitory Chromatin Environment at a Distal Enhancer of the Estrogen Receptor-α Gene by Ginny L. Powers (493853)

“…<div><p>Expression of the estrogen receptor-α (ERα) gene, <i>ESR1</i>, is a clinical biomarker used to predict therapeutic outcome of breast cancer. …”

Contrast- enhanced CT imaging in the arterial phase of a 78-year-old male patient with recurrent HCC. by Akira Fuchigami (8697924)

“…<p>a) Multiple HCC are seen in the whole liver before administration of lenvatinib. b) Enhancement lesions are decreased in diameters at 5 weeks after the initiation of lenvatinib.…”

Table_1_Characterization and Mutational Analysis of a Monogalactosyldiacylglycerol Synthase Gene OsMGD2 in Rice.docx by Rasbin Basnet (7121534)

“…The leaf of osmgd2 mutants showed reduced MGDG (∼11.6%) and DGDG (∼9.5%) content with chlorophyll a content decreased by ∼23%, consequently affecting the photosynthesis. …”

Fed State Prior to Hemorrhagic Shock and Polytrauma in a Porcine Model Results in Altered Liver Transcriptomic Response by Charles Determan Jr (579219)

“…Functional analysis of the response to shock and resuscitation confirmed several typical responses including carbohydrate metabolism, cytokine inflammation, decreased cholesterol synthesis, and apoptosis. Our findings also suggest that the fasting state, relative to a carbohydrate prefed state, displays decreased carbohydrate metabolism, increased cytoskeleton reorganization and decreased inflammation in response to hemorrhagic shock and reperfusion. …”

Fig 12 - by Matti Viluksela (321291)

“…<p>Geometric means of absolute concentrations (A) and average relative (B) concentrations of 5 most abundant BDE congeners and the sum of other congeners in different study areas during the first (1972–1986), second (1987–2001) and third (2002–2017) trimester of the study. …”

Individual data and box plots on ∑PCN of all samples. by Matti Viluksela (321291)

Fig 10 - by Matti Viluksela (321291)

Fig 16 - by Matti Viluksela (321291)

“…<p>Geometric means of absolute concentrations (A) and average relative (B) concentrations of DDT metabolites DDE, DDD and the parent compound DDT in different study areas during the first (1972–1986), second (1987–2001) and third (2002–2006) trimester of the study. …”

Fig 8 - by Matti Viluksela (321291)

Temporal trend of ∑PCN levels in osprey eggs in different study areas. by Matti Viluksela (321291)

“…<p>Blue circles indicate individual data, and a red regression line is shown if p<0.05 (two-sided regression analysis). …”

Fig 14 - by Matti Viluksela (321291)

Supplemental Figure S2 from Targeting RRM2 and Mutant BRAF Is a Novel Combinatorial Strategy for Melanoma by Nail Fatkhutdinov (14934183)

Theoretical Modeling (Sparkle RM1 and PM7) and Crystal Structures of the Luminescent Dinuclear Sm(III) and Eu(III) Complexes of 6,6,7,7,8,8,8- Heptafluoro-2,2-dimethyl-3,5-octanedi... by Aabid Bashir Ganaie (11265478)

“…Of the two metal centers, in a given complex, one has a distorted square antiprism arrangement and the other acquires a distorted dodecahedron geometry. …”

Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of <i>Nigella sativa</i> oil and antidiabetic drugs by Mahmoud Balbaa (4025558)

“…</p><p>Methods</p><p>T2DM-induced rats were orally and daily administrated 2.0 ml NSO, 100 mg metformin (MT), 0.8 mg glimepiride (GI) and different combinations (100 mg MT & 2.0 ml NSO, 0.8 mg GI & 2.0 ml NSO and 2.0 ml NSO & intraperitoneal injection of 1/100 LD50 of IOMe-AG538) per kg body weight for 21 days.</p><p>Results</p><p>A significant increase in the brain lipid peroxidation and decrease in the antioxidant status with peripheral and central production of pro-inflammatory mediators were observed in diabetes-induced rats. …”

Theoretical Modeling (Sparkle RM1 and PM7) and Crystal Structures of the Luminescent Dinuclear Sm(III) and Eu(III) Complexes of 6,6,7,7,8,8,8- Heptafluoro-2,2-dimethyl-3,5-octanedi... by Aabid Bashir Ganaie (11265478)

“…Of the two metal centers, in a given complex, one has a distorted square antiprism arrangement and the other acquires a distorted dodecahedron geometry. …”

Mechanism underlying sex-ratio distortion and selection of male-deleterious alleles in Kruger (A) and HiP (B). by Pim van Hooft (272911)

“…Increased relative fertility and decreased lifetime mating success have a net positive effect on male relative fitness. …”

Development of immune factors over visits in the AAF and AAF-syn treatment group as (A) scores and (B) loadings. by Diana M. Hendrickx (1507435)

“…A negative loading means that the NPX value of the immune factor decreases when the scores increase.…”

Data_Sheet_1_Dynamic changes of fecal microbiota in a weight-change model of Bama minipigs.docx by Bo Zeng (428742)

“…</p>Results<p>During the weight gain period (1~27 week), the alpha diversity of fecal microbiota exhibited a “down-up-down” fluctuations, initially decreasing, recovering in the mid-term, and decreasing again in the later stage. …”

Image_4_The effects of statins in patients with advanced-stage cancers - a systematic review and meta-analysis.jpeg by Qiang Zhou (29805)

“…</p>Results<p>Statin therapy was associated with a 26% decreased risk of overall survival (HR, 0.74; 95% CI, 0.67, 0.81), 26% decreased risk of cancer-specific survival (HR, 0.74; 95% CI, 0.61-0.88), and 24% decreased risk of progression-free survival (HR, 0.76; 95% CI, 0.65-0.87) for advanced-stage cancer patients. …”

Image_2_The effects of statins in patients with advanced-stage cancers - a systematic review and meta-analysis.jpeg by Qiang Zhou (29805)

“…</p>Results<p>Statin therapy was associated with a 26% decreased risk of overall survival (HR, 0.74; 95% CI, 0.67, 0.81), 26% decreased risk of cancer-specific survival (HR, 0.74; 95% CI, 0.61-0.88), and 24% decreased risk of progression-free survival (HR, 0.76; 95% CI, 0.65-0.87) for advanced-stage cancer patients. …”