A Tightly Controlled Conditional Knockdown System Using the <em>Tol2</em> Transposon-Mediated Technique by Tokuichi Iguchi (178202)

“…However, the application of this method to analyses in later stages of brain development or in the adult brain is still difficult because the amount of injected plasmids in a cell decreases along with development due to dilution by cell proliferation and the degradation of the plasmids. …”

During cortical development there is a switch from exocytosis dominated by spontaneous exocytosis to asynchronous and synchronous vesicle exocytosis. by Marijn B. Martens (769522)

“…<b>C</b>: By implementing the mRNA expression levels as ratios for SVE, aEVE and sEVE, a period of rapid learning is observed early in development during which SVE decreases and aEVE and sEVE increase. …”

RNA-seq analysis of <i>sig-7(RNAi)</i> embryos reveals a global transcription defect. by Jeong H. Ahn (3067842)

“…<p>RNA-seq was performed on RNA purified from <i>sig-7(RNAi)</i> and L4440 control RNAi embryos and the profiles compared. A) Volcano plot of normalized RNA-seq results showing the number of genes exhibiting significantly decreased (1549) and increased (362) RNA abundance in <i>sig-7(RNAi)</i> compared to L4440 (>2-fold differences with q value < 0.05). …”

0A ~ P amplitude and frequency control cell fate decision between biofilm matrix production and sporulation. by Cristina S. D. Palma (12024768)

“…., mild starvation), the amplitude of the 0A ~ P signal increases, its frequency decreases, and biofilm matrix production is activated stochastically in some cells (green line). …”

A Prospective Study of Bone Marrow Hematopoietic and Mesenchymal Stem Cells in Type 1 Gaucher Disease Patients by Séverine Lecourt (437757)

“…In order to evaluate the role of BM stem cells in GD pathophysiology, we prospectively analyzed BM-MSCs and HSPCs properties in a series of 10 patients with type 1 GD. GBA activity was decreased in all tested cell subtypes. …”

Table2_Fetal–neonatal exposure to antibiotics and NEC development: A systematic review and meta-analysis.docx by Daphne H. Klerk (10227647)

Association between testosterone with type 2 diabetes in adult males, a meta-analysis and trial sequential analysis by Jianzhong Zhang (135766)

“…Besides, trial sequential analysis was used to verify the pooled results.</p> <p>A total of 56 studies were enrolled in our meta-analysis. …”

Generation of a Tex signature from the T cell atlas and its network-based rescoring for target prioritization with Patrimony. by Adèle Mangelinck (17778420)

“…<p><b>(A)</b> Venn diagram of Tex scRNA-seq signatures. …”

Evolution of Extra-Nigral Damage Predicts Behavioural Deficits in a Rat Proteasome Inhibitor Model of Parkinson's Disease by Anthony C. Vernon (229125)

“…<div><p>Establishing the neurological basis of behavioural dysfunction is key to provide a better understanding of Parkinson's disease (PD) and facilitate development of effective novel therapies. …”

The effect of macronutrient and micronutrient fertilization on the abundance of brown food web arthropods in a coastal tallgrass prairie in Texas by Ryan Reihart (9174179)

“…</p><p><br></p><p>Abstract:</p><p>Nitrogen and phosphorus are thought to be the most important limiting nutrients in most terrestrial ecosystems, but little is known about how other elements may limit the abundance of arthropod communities. We utilized a fully factorial fertilization experiment that manipulated macronutrients (N&P, together) and micronutrients (calcium, sodium, potassium, separately), in large 30 x 30 m² plots and sampled litter arthropods via pitfall trapping to determine the nutrients that limit this group. …”

Image_1_HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease.jpeg by Sandra O. Braz (10748169)

“…Introduction<p>In Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine. …”

Alien Plants Introduced by Different Pathways Differ in Invasion Success: Unintentional Introductions as a Threat to Natural Areas by Petr Pyšek (124962)

“…The proportion of naturalized and invasive species among all introductions delivered by a particular pathway decreases with a decreasing level of direct assistance from humans associated with that pathway, from release and escape to contaminant and stowaway. …”

Data_Sheet_2_Longitudinal analysis of exposure to a low concentration of oxytetracycline on the zebrafish gut microbiome.XLSX by Masood ur Rehman Kayani (5486279)

“…<p>Oxytetracycline, a widely produced and administered antibiotic, is uncontrollably released in low concentrations in various types of environments. …”

Supplementary Material for: Effects and patient benefits of a 10% urea-based moisturizing lotion on xerosis in aging skin by figshare admin karger (2628495)

“…Introduction Skin senescence leads to decreased lipid and water levels, inducing xerosis with compromised barrier function. …”

DataSheet1_Cardiac ischemia modulates white adipose tissue in a depot-specific manner.pdf by Luzhou Wang (14021760)

“…We conclude that targeted interference with lipolysis in SAT may be a promising approach to promote cardiac healing after ischemia.…”

Image_1_HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease.jpeg by Sandra O. Braz (10748169)

“…Introduction<p>In Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine. …”

Data_Sheet_1_Longitudinal analysis of exposure to a low concentration of oxytetracycline on the zebrafish gut microbiome.DOCX by Masood ur Rehman Kayani (5486279)

“…<p>Oxytetracycline, a widely produced and administered antibiotic, is uncontrollably released in low concentrations in various types of environments. …”

Data Sheet 1_Factors affecting posaconazole plasma concentrations: a meta-analysis and systematic review.docx by Ruochen Qu (16946790)

“…Background<p>Posaconazole is a potent antifungal agent widely used to manage invasive fungal infections, especially in immunocompromised individuals. …”

Changes in facial skin blood-flow distribution in a subject before (Pre) and during (Stimulus) gustatory stimulation. by Hideaki Kashima (338536)

“…The white ellipses in the six facial regions represent the target areas where blood flow was measured. Sweet (a) and umami (b) stimuli characteristically increased eyelid skin blood flow, while bitter (c) stimuli decreased nose skin blood flow.…”

Multistability and snap-through behaviour of a bistable clamped strip from Adaptive compliant structures for flow regulation by Gaetano Arena (4332022)

“…The applied load increases until it reaches a critical value. At this point the beam snaps through a region of instability, where applied load decreases, reaching a second stable branch. …”