Efficacy and safety of corticosteroid regimens for the treatment of hospitalized COVID-19 patients: a meta-analysis: Supplementary data by Fangwen Zhou (9034640)

Early occurrence of primary angle-closure glaucoma in a patient with retinitis pigmentosa and CRB1 gene variations by Ricardo Yuji Abe (10366857)

“…<div><p>ABSTRACT We describe the case of a 15-year-old girl with decreased visual acuity associated with elevated intraocular pressure in both eyes and angle closure on gonioscopy. …”

A combination of CPI-613 and chloroquine significantly suppressed tumor growth in an orthotropic metastatic tumor model of CCS. by Yuki Egawa (5349512)

“…<p>A: Tumor volume at injection site with intraperitoneal injection of vehicle only, (Mock), CPI-613, chloroquine, or a combination of CPI-613 and chloroquine. …”

Evolutionarily Repurposed Networks Reveal the Well-Known Antifungal Drug Thiabendazole to Be a Novel Vascular Disrupting Agent by Hye Ji Cha (140719)

“…<div><p>Studies in diverse organisms have revealed a surprising depth to the evolutionary conservation of genetic modules. …”

Table_1_A large-scale forward genetic screen for maize mutants with altered lignocellulosic properties.docx by Shaogan Wang (14727736)

“…<p>The development of efficient pipelines for the bioconversion of grass lignocellulosic feedstocks is challenging due to the limited understanding of the molecular mechanisms controlling the synthesis, deposition, and degradation of the varying polymers unique to grass cell walls. Here, we describe a large-scale forward genetic approach resulting in the identification of a collection of chemically mutagenized maize mutants with diverse alterations in their cell wall attributes such as crystalline cellulose content or hemicellulose composition. …”

Disrupted Small-World Brain Networks in Moderate Alzheimer's Disease: A Resting-State fMRI Study by Xiaohu Zhao (175664)

“…<div><p>The small-world organization has been hypothesized to reflect a balance between local processing and global integration in the human brain. …”

Pediculectomy and fenestration for spinal cord decompression of the lumbar spine of a bush dog (Speothos venaticus) - case report by P.V.T. Marinho (5383583)

“…<div><p>ABSTRACT A captive adult male bush dog (Speothos venaticus) was referred to our Veterinary Medical Teaching Hospital from a local zoo due to a two-week history of progressive hind limb gait impairment and ataxia, non-responsive to clinical management. …”

Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor by LiMei Wang (5651041)

“…<div><p>The multifunctional signaling protein p75 neurotrophin receptor (p75^NTR) is a central regulator and major contributor to the highly invasive nature of malignant gliomas. …”

Data_Sheet_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.PDF by Ran Fang (533948)

“…<p>Pyoderma gangrenosum (PG) is a rare, destructive inflammatory skin disease of which a painful nodule or pustule breaks down to form a progressively enlarging ulcer. …”

Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties by Keigo Hirai (12095443)

“…Through IAM chromatography analysis and in vivo brain penetration assay of the HyTs, we discovered a brain-permeable HyT. Our results and mechanistic analysis indicate that conversion of protein degraders into HyTs could be a useful approach to improve their drug-like properties.…”

Table_1_A Novel Biallelic STING1 Gene Variant Causing SAVI in Two Siblings.doc by Malak Ali Alghamdi (9960260)

“…Exome sequencing revealed a novel homozygous NM_198282.3: c.841C>T; p.(Arg281Trp) variant in exon 7 of the STING1 gene. …”

Cross-Linking Porcine Pericardium by 3,4-Dihydroxybenzaldehyde: A Novel Method to Improve the Biocompatibility of Bioprosthetic Valve by Binggang Wu (9925999)

“…In conclusion, the properties of bioprosthetic valves could be effectively improved by processing valves with a DHBA-based cross-linking method.…”

Cone densities and opsin expression patterns along a dorso-ventral strip in temporal retina (aardvark 1). by Leo Peichl (219825)

“…<p>(A) Cone density along the dorso-ventral strip (region 1 in the retina scheme <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0314252#pone.0314252.s001" target="_blank">S1 Fig</a>) decreases with distance from the streak, the horizontal band of reduced pigmentation in the fundus (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0314252#pone.0314252.g003" target="_blank">Fig 3</a>). …”

Experimental and computational studies on a protonated 2-pyridinyl moiety and its switchable effect for the design of thermolytic devices by Jolanta Brzezinska (1456774)

“…Such protonation seems to be a major inhibitory factor in the thermal removal of 2-pyridynyl TPG by the “chemical switch” approach and decreases the aromaticity of the pyridine ring. …”

Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors by Jumpei Aida (1399486)

“…Monoacylglycerol lipase (MAGL) is a major serine hydrolase that hydrolyzes 2-arachidonoylglycerol (2-AG) to arachidonic acid (AA) and glycerol in the brain. …”

Changes in dietary habits and eating behaviors during COVID-19 induced confinement: A study from Jordan by Alomari, Mahmoud A.

“…Among these changes, they have increased (p < 0.05) the prevalence of fruit and vegetable, immune boosters, water, and hot beverage consumption, as well as decreased (p < 0.05) eating in restaurants and fatty food consumption, indicating a positive change. …”
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Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis by Paravattil, Bridget

“…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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Image_2_Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.JPEG by Ling Hu (374570)

“…<p>Schizophrenia (SCZ) is a chronic and severe mental disease that affects around 1% of the population. …”

HuR specifically represses translation through the IGF-IR 5′-UTR in a concentration-dependent manner by Zheng Meng (9293)

“…The FLuc RNA (5 ng) was used as a control. The results are expressed relative to the control reactions without HuR. () translation with recombinant HuR protein. …”

Deletion of <i>Kif3a</i> in early stages of forebrain development leads to increased brain size. by John Snedeker (3836410)

“…<p>(A-L) <i>Foxg1-Cre</i> was used to delete a conditional allele of <i>Kif3a</i> and the forebrain was enlarged at E14.5 (B) and E18.5 (H,J,). …”