Loss of <i>Fgf3</i> causes variable anterior-posterior axis truncation and caudal malformation. by Matthew J. Anderson (265883)

“…Bars in <b>F</b> and <b>G</b> indicate total PSM length, which is quantified in <b>N</b>. Note that a decrease in the amount of mutant PSM begins at 37 ss followed by a total loss of PSM around 54 ss, resulting with fewer somites in mutants. …”

Data Sheet 1_Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.pdf by Robert B. Rebhun (8479020)

“…We evaluated inhaled IL-15 combined with amputation and chemotherapy for localized canine OSA eligible for treatment with curative intent.</p>Methods<p>In a multicenter COTC phase-II-trial for dogs with limb OSA, we hypothesized 2 weeks of inhaled rhIL-15 after amputation and prior to chemotherapy would reduce the risk of metastatic failure at the completion of chemotherapy from a historical rate of 40% to 20%. …”

Construction of Recombinant HVT Expressing PmpD, and Immunological Evaluation against <i>Chlamydia psittaci</i> and Marek’s Disease Virus by Shanshan Liu (315561)

“…<i>psittaci</i> CB7 strain, a significant decrease in respiratory distress, lesions and <i>Chlamydia</i> load was found in the rHVT-<i>pmpD</i>-N-vaccinated group compared to the parental HVT. …”

STEP in-person sessions. by Shirley Yen (12632685)

“…Skills to Enhance Positivity (STEP) is an acceptance-based intervention, designed to increase attention to, and awareness of, positive affect and positive experiences. Results from a pilot RCT demonstrated engagement of the target (positive affect) and a decrease in clinical outcomes (suicidal events; i.e., either a suicide attempt or an emergency intervention for an acute suicidal crisis), providing support to test the clinical effectiveness of STEP in a larger clinical trial with clinical staff implementing the intervention.…”

Effect of MMA on luciferase reporter activity in HepG2 cells transfected with vectors containing <i>Gsta1</i>-ARE. by Ai Orimoto (389831)

“…<p>(A) Structures of reporter constructs. The vector pGL4.10-<i>Gsta1</i>pro990 contains 5′-flanking region (-990 to +46; the 41-bp of ARE region is located -729 to -689) immediately upstream of the synthetic firefly luciferase reporter gene (<i>luc2</i>), which was previously constructed <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058907#pone.0058907-Hattori1" target="_blank">[16]</a>. …”

Table1_Shale Heavy Metal Isotope Records of Low Environmental O2 Between Two Archean Oxidation Events.XLSX by Chadlin M. Ostrander (12460062)

“…Sylvia formations preserved in drill core ABDP9). We find a progressive decrease in bulk-shale Fe isotope compositions moving up core (as low as δ⁵⁶Fe = –0.78 ± 0.08‰; 2SD) accompanied by invariant authigenic Tl isotope compositions (average ε²⁰⁵Tl_A = –2.0 ± 0.6; 2SD) and bulk-shale U isotope compositions (average δ²³⁸U = –0.30 ± 0.05‰; 2SD) that are both not appreciably different from crustal rocks or bulk silicate Earth. …”

Proportion of dead and alive neonates. by Sujan Kumar Naha (20577028)

“…Among them, 23.07% received a single dose, and 22.82% took adequate doses (receiving more than two doses) and adhered to WHO guidelines. …”

Supramolecular Luminescent Gold(I)−Copper(I) Complexes: Self-Assembly of the Au_<i>x</i>Cu_<i>y</i> Clusters inside the [Au₃(diphosphine)₃... by Igor O. Koshevoy (1444258)

“…Photophysical experiments demonstrate that an increase of the size of the aggregates leads to a decrease in photostability and photoefficiency. …”

Table_2_Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.XLSX by Marie Isabel Rasmussen (11110416)

“…There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019).…”

EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer - Fig 9 by Stephanie Rossnagl (553093)

“…<p><b>Myeloid cells are intrinsically different based on exposure to EDA-FN.</b> (A) Adoptive transfer using similar numbers of isolated CD11b⁺-cells from cKO and CT animals mixed with B16 melanoma cells and injected subcutaneously showed a significant decrease in growth in the tumors that contained cKO CD11b⁺-cells, <i>n</i> = 16/10/18/18. …”

Image_1_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_1_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_3_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_3_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Chronic High Fructose Intake Reduces Serum 1,25 (OH)₂D₃ Levels in Calcium-Sufficient Rodents by Veronique Douard (549533)

“…Replacing glucose with fructose prevented these increases in Ca²⁺ transporter, CYP27B1, and 1,25(OH)₂D₃ levels induced by a low Ca²⁺ diet. In adult mice fed for three mo a normal Ca²⁺ diet, renal expression of CYP27B1 and of CYP24A1 (24-hydroxylase) decreased and increased, respectively, when the carbohydrate source was fructose instead of glucose or starch. …”

Timeline of interventions and assessments. by Shirley Yen (12632685)

“…Skills to Enhance Positivity (STEP) is an acceptance-based intervention, designed to increase attention to, and awareness of, positive affect and positive experiences. Results from a pilot RCT demonstrated engagement of the target (positive affect) and a decrease in clinical outcomes (suicidal events; i.e., either a suicide attempt or an emergency intervention for an acute suicidal crisis), providing support to test the clinical effectiveness of STEP in a larger clinical trial with clinical staff implementing the intervention.…”

DataSheet_1_Differential regulatory T cell signature after recovery from mild COVID-19.pdf by Pedro Henrique de Sousa Palmeira (14758156)

“…Interestingly, Pool Spike CoV-2 elicited a decrease in Treg IL-17⁺ frequency in the Severe Recovered group. …”

Factor associated with neonatal mortality. by Sujan Kumar Naha (20577028)

“…Among them, 23.07% received a single dose, and 22.82% took adequate doses (receiving more than two doses) and adhered to WHO guidelines. …”

Table1_Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms... by Pei Teng Lum (16537509)

“…Further, a significant depletion in brain malondialdehyde (MDA) level, an increase in reduced glutathione (GSH) level, succinate dehydrogenase (SDH), superoxide dismutase (SOD) and catalase (CAT) activities, and a decrease in tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β) and interleukin-6 (IL-6) levels were observed in mangiferin treated groups. …”

Image_2_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”