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145061
Table_1_Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production.DOCX
Published 2020“…Herein, DHAA biosynthesis was achieved in Saccharomyces cerevisiae by introducing a series of heterologous enzymes: ADS (amorpha-4,11-diene synthase), CYP71AV1 (amorphadiene oxidase), ADH1, DBR2 and ALDH1, obtaining initial DHAA/AA ratio at 2.53. …”
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145062
Image 6_Global ischemic heart disease burden attributable to environmental risk factors, 1990–2021: an Age-Period-Cohort analysis.tiff
Published 2025“…</p>Conclusion<p>IHD burden attributable to environmental factors shows a declining trend globally but with notable regional and gender disparities. …”
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145063
Table2_Phosphoenolpyruvate carboxykinase 2-mediated metabolism promotes lung tumorigenesis by inhibiting mitochondrial-associated apoptotic cell death.DOCX
Published 2024“…</p>Methods<p>RNA-seq, Western blot and RT-PCR were performed in A549 cell lines cultured in medium containing low or high concentrations of glucose (1 mM vs. 20 mM) to gain insight into how cancer cells rewire their metabolism under glucose-restriction conditions. …”
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145064
Notch3 overexpression causes arrest of cell cycle progression by inducing Cdh1 expression in human breast cancer cells
Published 2015“…Conversely, silencing of Notch3 in the breast cancer cell line, MCF-7, caused a decrease in expression levels of Cdh1 and p27<sup>Kip </sup>at both the protein and mRNA levels, while the expression of Skp2 only increased at the protein level. …”
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145065
Formation of Formic Acid Derivatives through Activation and Hydroboration of CO<sub>2</sub> by Low-Valent Group 14 (Si, Ge, Sn, Pb) Catalysts
Published 2020“…The trend in reactivity found in the present study is a direct consequence of the change in the central main group element, enabling enhanced polar character of the E–H (L<sup>1</sup>EH in the CO<sub>2</sub> activation step) and E–O (metal formates in the hydroboration step) bonds as the atomic radius increases. …”
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145066
Presentation_1_Effects of plastic film mulching on soil microbial carbon metabolic activity and functional diversity at different maize growth stages in cool, semi-arid regions.pdf
Published 2024“…A similar trend was observed for the microbial functional diversity index. …”
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145067
Table_5_Vitamins and Helicobacter pylori: An Updated Comprehensive Meta-Analysis and Systematic Review.docx
Published 2022“…Background<p>Over recent decades, epidemiological studies have shown relationships between vitamins and Helicobacter pylori (H. pylori) infection and eradication, but the results are controversial.</p>Methods<p>A comprehensive meta-analysis and systematic review were conducted to clarify the relationships between common types of vitamins and H. pylori. …”
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145068
Data_Sheet_1_DHAV-1 Inhibits Type I Interferon Signaling to Assist Viral Adaption by Increasing the Expression of SOCS3.docx
Published 2019“…<p>Duck hepatitis A virus type 1 (DHAV-1) is one of the most lethal pathogens in the duck industry. …”
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145069
Image_2_The Association of Maternal Emotional Status With Child Over-Use of Electronic Devices During the COVID-19 Pandemic.TIF
Published 2021“…These findings may contribute to a better understanding of factors leading to over-use of electronic-device and developing strategies to decrease over-use during COVID-19.…”
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145070
Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to Improve Chemotherapy and Radiotherapy Efficacy
Published 2009“…Erlotinib followed by radiation inhibited tumor regrowth to a greater degree than did radiation alone, although the interaction between erlotinib and radiation was not synergistic.…”
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145071
Data_Sheet_1_Trichoderma erinaceum Bio-Priming Modulates the WRKYs Defense Programming in Tomato Against the Fusarium oxysporum f. sp. lycopersici (Fol) Challenged Condition.zip
Published 2019“…Overall, we conclude that T. erinaceum bio-priming modulated the defense transcriptome of tomato after the Fol challenged conditions, and were accompanied by enhanced accumulation of defense-related WRKY transcripts, increased antioxidative enzyme activities, and the reinforcements through a higher number of lignified cell layers.</p>…”
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145072
Image_8_Early Growth Response Gene-2 Is Essential for M1 and M2 Macrophage Activation and Plasticity by Modulation of the Transcription Factor CEBPβ.jpg
Published 2018“…Polarisation with M2-like stimuli (IL-4 or IL-13) results in increased Egr2 expression, but macrophages stimulated with M1-like stimuli (IFNγ, LPS, IL-6, or TNF) exhibit a decrease in Egr2 expression. Egr2 was critical for the expression of transcription factors CEBPβ and PPARγ in M2 macrophages, and CEBPβ was highly expressed in M1-polarized macrophages. …”
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145073
Table1_Study on MCFC-integrated GSCC systems with SEGR in parallel or series and CO2 capture.DOCX
Published 2023“…In these two new gas–steam combined cycle systems, SEGR connected with MCFC, either in parallel or series, increases CO<sub>2</sub> concentration beyond 11%. A gas–steam combined cycle system combined with MCFC and CO<sub>2</sub> capture without SEGR is used as the reference system. …”
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145074
Image_4_Multi-System Adaptation to Confinement During the 180-Day Controlled Ecological Life Support System (CELSS) Experiment.jpeg
Published 2019“…The 180-day Chinese CELSS (Controlled Ecological Life Support System) study is unique in its design, including a closed-loop system and mid-mission simulation of Mars-like day–night cycle of 24 h 40 min for 36 days (days 72–108). …”
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145075
DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic ac...
Published 2021“…The top birthweight-associated dmCpG was located within the Homeobox Telomere-Binding Protein 1 (HMBOX1) gene with a 195 g (95%CI: −241, −149 g) decrease in birthweight per 10% increase in methylation, while the top DMR was located within the promoter of corticotropin-releasing hormone-binding protein (CRHBP). …”
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145076
Butterfly M<sub>2</sub><sup>III</sup>Er<sub>2</sub> (M<sup>III</sup> = Fe and Al) SMMs: Synthesis, Characterization, and Magnetic Properties
Published 2018“…These two complexes are isostructural, possessing a planar butterfly motif with the Er<sup>III</sup> ions in the wingtip positions. …”
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145077
Overexpression of mutant ATXN2 in human SH-SY5Y cells recapitulates down-regulation of <i>in vivo</i> steady-state levels of Rgs8 in BAC-Q72 mice.
Published 2015“…Forty-eight hrs post-transfection, cells were selected with hygromycin (40 µg/ml) for 5–7 days and hygromycin resistant cells were harvested as two aliquots. <b>(A)</b> Protein extracts were prepared from one aliquot and subjected to Western blot analyses to measure steady-state levels of RGS8. …”
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145078
Table_1_Condensed Tannins in White Clover (Trifolium repens) Foliar Tissues Expressing the Transcription Factor TaMYB14-1 Bind to Forage Protein and Reduce Ammonia and Methane Emis...
Published 2022“…The CTs consisted predominantly of prodelphinidins (PD, 75–93%) and procyanidins (PC, 17–25%) and had a mean degree of polymerization (mDP) of approximately 10 flavan-3-ol subunits. …”
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145079
Low Socioeconomic Status Is Associated with Prolonged Times to Assessment and Treatment, Sepsis and Infectious Death in Pediatric Fever in El Salvador
Published 2012“…Providing additional education to high-risk families and staying at a nearby guest house during periods of neutropenia may decrease sepsis and infectious mortality.…”
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145080
Data_Sheet_9_Bioactive strawberry fruit (Arbutus unedo L.) extract remedies paraquat-induced neurotoxicity in the offspring prenatally exposed rats.xlsx
Published 2023“…Background<p>Paraquat (1,1′-dimethyl-4-4′-bipyridinium dichloride) exposure is well-established as a neurotoxic agent capable of causing neurological deficits in offspring. …”