TGFβ signaling promotes NDR1 turnover. by Isabelle Pot (427025)

“…<p><b>A.</b> Lysates of untreated or 48h-TGFβ-treated NMuMG cells in the absence or presence of the TGFβ type I receptor kinase inhibitor SB431542 (KI) were subjected to immunoblotting with the NDR1 or actin antibody. …”

Novel Heterometallic Schiff Base Complexes Featuring Unusual Tetranuclear {Co^III₂Fe^III₂(μ-O)₆} and Octanuclear {Co<sup>III</s... by Eduard N. Chygorin (2131984)

“…Variable-temperature (1.8–300 K) magnetic susceptibility measurements showed a decrease of the μ_B value at low temperature, indicative of antiferromagnetic coupling (<i>J</i>/<i>hc</i> = −32 cm^–1 in <b>1</b>; <i>J</i>/<i>hc</i> = −20 cm^–1 in <b>2</b>) between the Fe^III magnetic centers in both compounds. …”

Image_1_Analysis of the Characteristics of TIGIT-Expressing CD3−CD56+NK Cells in Controlling Different Stages of HIV-1 Infection.tif by Xin Zhang (35492)

“…In both HIV-1-infected individuals and healthy donors, TIGIT was predominantly expressed in NKG2A⁻NKG2C⁺NK cells, with a significantly higher proportion than in NKG2A⁺NKG2C⁻NK cells. …”

Rate Coefficient Measurements and Theoretical Analysis of the OH + (<i>E</i>)‑CF₃CHCHCF₃ Reaction by Munkhbayar Baasandorj (1813510)

“…In addition, the 296 K rate coefficient for the O₃ + (<i>E</i>)-CF₃CHCHCF₃ reaction was determined to be <5.2 × 10^–22 cm³ molecule^–1 s^–1. A theoretical computational analysis is presented to interpret the observed positive temperature dependence for the addition reaction and the significant decrease in OH reactivity compared to the (<i>Z</i>)-CF₃CHCHCF₃ stereoisomer reaction. …”

AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells by Nina Meyer (4888165)

“…Global proteomic analysis of AT 101-treated U87MG and U343 glioma cells revealed a robust decrease in mitochondrial protein clusters, whereas HMOX1 (heme oxygenase 1) was strongly upregulated. …”

Potential Regulatory Role of Human-Carboxylesterase‑1 Glycosylation in Liver Cancer Cell Growth by Keun Na (1666186)

“…Fluorescence 2-D difference gel electrophoresis protein expression analysis of cell lysates revealed an increase in cell growth and a decrease in doubling time in cells carrying the N79Q mutation. …”

Search terms. by Lucy Thompson (3705940)

“…The CCAT quality ratings ranged from 71% to 95%, with a mean of 82%. Puberty suppression (PS) was generally induced with Gonadotropin Releasing Hormone analogues (GnRHa), and at a pooled mean age of 14.5 (±1.0) years. …”

PRISMA diagram. by Lucy Thompson (3705940)

“…The CCAT quality ratings ranged from 71% to 95%, with a mean of 82%. Puberty suppression (PS) was generally induced with Gonadotropin Releasing Hormone analogues (GnRHa), and at a pooled mean age of 14.5 (±1.0) years. …”

PRISMA 2020 checklist. by Lucy Thompson (3705940)

“…The CCAT quality ratings ranged from 71% to 95%, with a mean of 82%. Puberty suppression (PS) was generally induced with Gonadotropin Releasing Hormone analogues (GnRHa), and at a pooled mean age of 14.5 (±1.0) years. …”

Novel Heterometallic Schiff Base Complexes Featuring Unusual Tetranuclear {Co^III₂Fe^III₂(μ-O)₆} and Octanuclear {Co<sup>III</s... by Eduard N. Chygorin (2131984)

“…Variable-temperature (1.8–300 K) magnetic susceptibility measurements showed a decrease of the μ_B value at low temperature, indicative of antiferromagnetic coupling (<i>J</i>/<i>hc</i> = −32 cm^–1 in <b>1</b>; <i>J</i>/<i>hc</i> = −20 cm^–1 in <b>2</b>) between the Fe^III magnetic centers in both compounds. …”

EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer - Fig 7 by Stephanie Rossnagl (553093)

“…<p><b>Loss of osteoblast-FN diminishes melanoma cancer growth.</b> (A) Melanoma B16 subcutaneous tumors showed delayed growth in cKO animals compared to CT. …”

Requirement of NF-κB activation for cytokine-mediated reductions in TEER. by Paul R. Clark (714064)

“…F: Effects of SR-IκB dominant negative overexpression on IL-1β-leak (ECIS). Note that IL-1β over a 12 hour time course was ineffective at decreasing TEER in SR-IκB-transduced HDMEC. …”

Data_Sheet_1_Inhibiting methanogenesis by targeting thermodynamics and enzymatic reactions in mixed cultures of rumen microbes in vitro.PDF by Kairi Tanaka (19418200)

“…Here, we provide a proof of concept that the combination of an electron acceptor and a methane analog may be exploited to improve microbial efficiency via methanogenesis inhibition.…”

Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication by Jun Li (6494)

“…<div><p>In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous bupivacaine, followed by an intravenous injection of adrenalin or isoprenalin, and the electrocardiogram (ECG), left ventricular systolic pressure (LVSP), left ventricular end-diastolic pressure (LVEDP), the maximum rate of rise of left ventricular pressure (+dP/dtmax) and the maximum rate of pressure decrease (-dP/dtmax) were continually monitored. …”

Determinant of Selective Removal (DSR) sequences can reduce protein levels expressed from P<i>_urg1lox</i>. by Adam T. Watson (500083)

“…<p>(<b>A</b>). Schematic of the P<i>_urg1lox</i> locus following RCME to introduce yEGFP under the control of the <i>urg1</i> promoter. …”

Image_2_Analysis of the Characteristics of TIGIT-Expressing CD3−CD56+NK Cells in Controlling Different Stages of HIV-1 Infection.tif by Xin Zhang (35492)

“…In both HIV-1-infected individuals and healthy donors, TIGIT was predominantly expressed in NKG2A⁻NKG2C⁺NK cells, with a significantly higher proportion than in NKG2A⁺NKG2C⁻NK cells. …”

Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in mice by Katsutaka Oishi (278169)

“…The DF-induced increases in body weight gain, food efficiency, adipose tissue mass, lipogenic gene expression in metabolic tissues, and hepatic lipid accumulation were abolished in <i>db</i>/<i>db</i> mice, suggesting that the leptin resistance is a cause of DF-induced metabolic disorders. DF resulted in deep hypothermia in <i>db</i>/<i>db</i>, as well as in wild-type mice, suggesting that a decrease in energy expenditure was not the main cause of DF-induced obesity. …”

Pathways identified by IPA connects Bacopa to memory, neuroprotection and AD. by How-Wing Leung (4385896)

“…Explanation of the numbered connections: (1) ATF4 and NRF2 functionally interact with each other [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref040" target="_blank">40</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref043" target="_blank">43</a>]. (2) ATF4 is implicated in memory [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref059" target="_blank">59</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref062" target="_blank">62</a>]. (3) NRF is implicated in memory [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref063" target="_blank">63</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref067" target="_blank">67</a>]. (4) Translation initiation factor eIF2-alpha stimulates translation of ATF4 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref068" target="_blank">68</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref071" target="_blank">71</a>]. (5) eIF2-alpha is implicated in memory formation [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref072" target="_blank">72</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref073" target="_blank">73</a>]. (6) ATF4 has been implicated in Alzheimer’s disease (AD) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref074" target="_blank">74</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref078" target="_blank">78</a>]. (7) NRF2 has also been linked to AD [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref063" target="_blank">63</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref065" target="_blank">65</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref067" target="_blank">67</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref079" target="_blank">79</a>]. (8) NRF2 plays a critical role in neuroprotection [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref080" target="_blank">80</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref083" target="_blank">83</a>]. (9) FOXO3 mediates oxidative stress-induced neuronal cell death [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref084" target="_blank">84</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182984#pone.0182984.ref087" target="_blank">87</a>]. …”

Genome-wide genic copy numbers for nine Macaca species based on 1kb windows by Jing Li (7426562)

“…Unplaced contigs were merged as ‘chrUn’ in data processing to decrease the CPU time.</p><p> </p><p>Bolger AM, Lohse M, Usadel B (2014) Trimmomatic: a flexible trimmer for Illumina sequence data. …”

<i>Dpp</i> expression increases after inducing apoptosis in eye discs. by Sergio B. Velarde (11261991)

“…(C–C”” and F-F””) Higher magnification images corresponding to the regions highlighted by white rectangles on the panels B (C–C””) and E (F-F””). (A–B”) In control eye discs, Dpp is expressed in a band of cells just anterior to the MF, and its expression levels decrease abruptly to a homogeneous low level behind the furrow. …”