Image4_Effect of pro-inflammatory cytokine priming and storage temperature of the mesenchymal stromal cell (MSC) secretome on equine articular chondrocytes.TIF by Manon Jammes (16910904)

“…The three cytokines chosen for the MSC priming influenced MSC immunomodulator gene expression, although each cytokine led to a different pattern of MSC immunomodulation. The cytokine-primed CM had no major effect on eAC proliferation, with IL-1β and TNF-α slightly increasing collagen (types IIB and I) accumulation in eAC 3D cultures (particularly with the CM derived from MSCs primed with IL-1β), and IFN-γ leading to a marked decrease. …”

DataSheet1_Effect of pro-inflammatory cytokine priming and storage temperature of the mesenchymal stromal cell (MSC) secretome on equine articular chondrocytes.pdf by Manon Jammes (16910904)

“…The three cytokines chosen for the MSC priming influenced MSC immunomodulator gene expression, although each cytokine led to a different pattern of MSC immunomodulation. The cytokine-primed CM had no major effect on eAC proliferation, with IL-1β and TNF-α slightly increasing collagen (types IIB and I) accumulation in eAC 3D cultures (particularly with the CM derived from MSCs primed with IL-1β), and IFN-γ leading to a marked decrease. …”

Table2_Serum and brain metabolomic study reveals the protective effects of Bai-Mi-Decoction on rats with ischemic stroke.DOCX by Lingling Yang (525847)

“…<p>Bai-Mi-Decoction (BMD), which is composed of Eugenia caryophyllata, Myristica fragrans, Moschus berezovskii, and Crocus sativu, is a characteristic TCM multi-herb formula for brain disease. …”

Table1_Serum and brain metabolomic study reveals the protective effects of Bai-Mi-Decoction on rats with ischemic stroke.DOCX by Lingling Yang (525847)

“…<p>Bai-Mi-Decoction (BMD), which is composed of Eugenia caryophyllata, Myristica fragrans, Moschus berezovskii, and Crocus sativu, is a characteristic TCM multi-herb formula for brain disease. …”

Table1_Placental treatment with insulin-like growth factor 1 via nanoparticle differentially impacts vascular remodeling factors in guinea pig sub-placenta/decidua.DOCX by Baylea N. Davenport (14324355)

“…Additionally, there are no effective in utero treatment options for FGR. We have developed a nanoparticle to deliver human insulin-like 1 growth factor (hIGF-1) in a trophoblast-specific manner which results in increased expression of hIGF-1. …”

DataSheet2_Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental V... by Qing Liu (20889)

“…</p><p>Results: In total, 63 chemical compounds from ELZC and 365 putative ARHL-related targets were identified, and 1860 ARHL-related targets were collected from the OMIM and GeneCards. A total of 145 shared targets of ELZC and ARHL were acquired by Venn diagram analysis. …”

Data Sheet 1_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…</p>Conclusion<p>This study elucidates the HSP90AA1-HSPA1B-DNAJB1 network as a key driver of VaD pathogenesis through dual mechanisms of protein homeostasis and immune reprogramming. …”

Data_Sheet_1_Association Between Living Risk and Healthy Life Years Lost Due to Multimorbidity: Observations From the China Health and Retirement Longitudinal Study.docx by Xinlei Miao (11086052)

“…</p>Conclusions<p>These findings indicate that a low-risk lifestyle could decrease the loss of healthy life years under multimorbidity. …”

DataSheet1_v1_Life Cycle Assessment of Power-to-Syngas: Comparing High Temperature Co-Electrolysis and Steam Methane Reforming.docx by Andrea Schreiber (5088317)

“…Although plant construction contributes to a minor extent to most impact categories, a considerable decrease of cell lifetime due to higher degradation caused by flexible operation, would change that. …”

DataSheet_1_Endogenous CCN5 Participates in Angiotensin II/TGF-β1 Networking of Cardiac Fibrosis in High Angiotensin II-Induced Hypertensive Heart Failure.docx by Anan Huang (9335846)

“…A negative association was observed between CCN5 and Ang II in grade 2and 3 hypertensive patients receiving ACEI treatment. …”

Table_1_Tandem mass tag labeled quantitative proteomic analysis of differential protein expression on total alkaloid of Aconitum flavum Hand.-Mazz. against melophagus ovinus.DOCX by Xinjian Wang (711385)

“…<p>Melophagus ovinus disease is a common ectoparasitosis, which can lead to a decrease in animal production performance, product quality, and even death. …”

MRI reveals menstrually-related muscle edema that negatively affects athletic agility in young women by Akemi Sawai (4794633)

“…Progesterone levels decreased significantly in the menstrual phase and the follicular phase compared to the ovulatory phase (<i>P</i> = 0.012, <i>P</i> = 0.009 respectively), the early luteal phase (both <i>P</i> = 0.007), and the late luteal phase (<i>P</i> = 0.028, <i>P</i> = 0.029 respectively), and it along with a significant decrease in the ovulatory phase compared to the early luteal phase (<i>P</i> = 0.010). …”

DataSheet_1_CXCR4 Inhibition Counteracts Immunosuppressive Properties of Metastatic NSCLC Stem Cells.docx by Orazio Fortunato (3522623)

“…Notably, we observed a decreased expression of CD73, CD38, and IL-10 following CXCR4 inhibition. …”

Table_2_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…Background<p>Systemic hypoperfusion plays a pivotal role in the pathogenesis of primary open-angle glaucoma (POAG). …”

Datasheet1_Effectiveness of an online mental health strengthening module to build resilience and overcome stress for transitional aged medical students.pdf by Fransiska Kaligis (11685118)

“…Additionally, compared to the control group, there were significant increases in knowledge [F(1, 103) = 66.805, P < .001], attitudes and behavior towards mental-health [F(1, 103) = 5.191, P = .025], and a significant decrease in stress perception score [F(1, 103) = 27.567, P < .001]. …”

Table1_Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental Valid... by Qing Liu (20889)

“…</p><p>Results: In total, 63 chemical compounds from ELZC and 365 putative ARHL-related targets were identified, and 1860 ARHL-related targets were collected from the OMIM and GeneCards. A total of 145 shared targets of ELZC and ARHL were acquired by Venn diagram analysis. …”

Rapid postnatal ^ret<i>Cep164</i>^-/- photoreceptor degeneration. by Michelle Reed (391022)

“…<p><b>A-C</b>, P6 <i>Cep164</i>^+/F (A), ^ret<i>Cep164</i>^<i>-/-</i> central (B) and peripheral (C) cryosections on Egfp-Cetn2⁺ background probed with anti-CEP164 antibody (red). …”

Table2_Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental Valid... by Qing Liu (20889)

“…</p><p>Results: In total, 63 chemical compounds from ELZC and 365 putative ARHL-related targets were identified, and 1860 ARHL-related targets were collected from the OMIM and GeneCards. A total of 145 shared targets of ELZC and ARHL were acquired by Venn diagram analysis. …”

Insights into the Fragmentation of Aluminum Hydride and Its Effect on Combustion and Agglomeration of HTPB Propellant by Zhoufeng Jiang (1736425)

“…Compared to raw particles, the CCPs (condensed combustion products) of SP2 propellant display a 48% reduction in average size (<i>D</i>₅₀ = 24.5 μm), whereas there is an over 89% decrease in particle size for the CCPs of SP3 propellant (<i>D</i>₅₀ = 5.14 μm). …”

Image3_NVP-BEZ235 Inhibits Renal Cell Carcinoma by Targeting TAK1 and PI3K/Akt/mTOR Pathways.JPEG by Bihui Li (11924447)

“…Likewise, in vivo, treatment with NVP-BEZ235 and PP242 suppressed the growth of xenografts generated from 786-0 and A498 cells, along with decreased expression of phospho-TAK1, phospho-c-Jun, and phospho-IκB-α. …”