Cross-Conjugated Systems Based On An (<i>E</i>)‑Hexa-3-en-1,5-diyne-3,4-diyl Skeleton: Spectroscopic and Spectroelectrochemical Investigations by Josef B. G. Gluyas (1478950)

“…The linear optical absorption properties can be tuned by modification of the substituents at the 1 and 5 positions of the hexa-3-en-1,5-diynyl backbone (<b>1</b>: Si­(CH­(CH₃)₂)₃, <b>2</b>: C₆H₄CCSi­(CH₃)₃, <b>3</b>: C₆H₄COOCH₃, <b>4</b>: C₆H₄CF₃, <b>5</b>: C₆H₄CN, <b>6</b>: C₆H₄CCC₅H₄N), although attempts to introduce electron-donating (C₆H₄CH₃, C₆H₄OCH₃, C₆H₄Si­(CH₃)₃) substituents at these positions were hampered by the ensuing decreased stability of the compounds. …”

Table_2_Verification of Resveratrol Inhibits Intestinal Aging by Downregulating ATF4/Chop/Bcl-2/Bax Signaling Pathway: Based on Network Pharmacology and Animal Experiment.xls by Tian-hao Liu (9109460)

“…Herein, we aimed to further explore the pharmacological mechanisms of resveratrol as a therapy for intestinal aging. We performed network construction and enrichment analysis via network pharmacology. …”

Table_7_Verification of Resveratrol Inhibits Intestinal Aging by Downregulating ATF4/Chop/Bcl-2/Bax Signaling Pathway: Based on Network Pharmacology and Animal Experiment.xls by Tian-hao Liu (9109460)

“…Herein, we aimed to further explore the pharmacological mechanisms of resveratrol as a therapy for intestinal aging. We performed network construction and enrichment analysis via network pharmacology. …”

Cross-Conjugated Systems Based On An (<i>E</i>)‑Hexa-3-en-1,5-diyne-3,4-diyl Skeleton: Spectroscopic and Spectroelectrochemical Investigations by Josef B. G. Gluyas (1478950)

“…The linear optical absorption properties can be tuned by modification of the substituents at the 1 and 5 positions of the hexa-3-en-1,5-diynyl backbone (<b>1</b>: Si­(CH­(CH₃)₂)₃, <b>2</b>: C₆H₄CCSi­(CH₃)₃, <b>3</b>: C₆H₄COOCH₃, <b>4</b>: C₆H₄CF₃, <b>5</b>: C₆H₄CN, <b>6</b>: C₆H₄CCC₅H₄N), although attempts to introduce electron-donating (C₆H₄CH₃, C₆H₄OCH₃, C₆H₄Si­(CH₃)₃) substituents at these positions were hampered by the ensuing decreased stability of the compounds. …”

Table_4_Verification of Resveratrol Inhibits Intestinal Aging by Downregulating ATF4/Chop/Bcl-2/Bax Signaling Pathway: Based on Network Pharmacology and Animal Experiment.xls by Tian-hao Liu (9109460)

“…Herein, we aimed to further explore the pharmacological mechanisms of resveratrol as a therapy for intestinal aging. We performed network construction and enrichment analysis via network pharmacology. …”

DataSheet1_Transcriptomic profiles of age-related genes in female trachea and bronchus.pdf by Jia Liu (41593)

“…</p><p>Conclusion: We found the proportion of basal cells decreased with age in both the trachea and bronchus, suggesting a weakening of their self-renew ability with age. …”

Table_6_Verification of Resveratrol Inhibits Intestinal Aging by Downregulating ATF4/Chop/Bcl-2/Bax Signaling Pathway: Based on Network Pharmacology and Animal Experiment.xls by Tian-hao Liu (9109460)

“…Herein, we aimed to further explore the pharmacological mechanisms of resveratrol as a therapy for intestinal aging. We performed network construction and enrichment analysis via network pharmacology. …”

X-ChIP based affinity purification provides the most inclusive analysis of nucleoid associated proteins. by Nina Rajala (693865)

“…The pie-chart shown here illustrates the distribution of the 366 enriched proteins identified with the X-ChIP method in regular HEK293 TwinkleFLAG and measured in HEK293 TwinkleFLAG ρ° in the following classes: not detected (absent), 95 proteins; ≥2 fold decrease, 163 proteins; no change, 100 proteins or ≥2 fold increase, 8 proteins(see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116726#pone.0116726.s004" target="_blank">S3 Table</a>). …”

CONSORT 2010 flow diagram. by Mario Daidone (18692907)

“…Moreover, these findings provide an additional plausible interpretation of the results from observational and cohort studies linking high adherence to a Mediterranean-style diet with lower total mortality and a decrease in cardiovascular events and cardiovascular mortality.…”

Mapping the properties of cells in relation to their local neighborhood. by Matthew French (13007466)

“…This shows a decrease in NR, indicating TBX6+ high cells are surrounded by cells expressing lower TBX6 levels than expected within a random pattern. …”

Suppression of APP maturation and proteolytic metabolism by the PDZ domains of X11 proteins. by Yuhki Saito (145216)

“…Data were analyzed using the Student's <i>t</i>-test (*, <i>P</i><0.05; **, <i>P</i><0.01; ***, <i>P</i><0.001). Proteins showing a significant decrease (P<0.01 and P<0.001) in Aβ generation are shown as closed columns.…”

Hexadentate Hydroxypyridonate Iron Chelators Based on TREN-Me-3,2-HOPO:  Variation of Cap Size¹ by Jide Xu (1446652)

“…The incremental enlargement of ligand size results in a decrease in iron-chelate stability, as reflected in the log β₁₁₀ values of 26.8, 26.2, 26.42, and 24.48 for the TREN, TR322, TR332, and TRPN derivatives, respectively. …”

MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus by Yun Deng (67804)

“…<i>TLR7</i> 3′UTR sequence bearing the non-risk C allele of rs3853839 matches a predicted binding site of microRNA-3148 (miR-3148), suggesting that this microRNA may regulate <i>TLR7</i> expression. …”

Retinal morphology and function is damaged in TALEN <i>clcc1</i>-KO zebrafish. by Lin Li (28817)

“…<i>clcc1</i> KO embryos show destruction of the rod photoreceptor layer (b) compared with WT (a). While somewhat better preserved than in the morpholino <i>clcc1</i> knockdown embryos, cone photoreceptors and the other retinal layers also appear decreased. …”

Effects of KU-55933 and metformin on metabolism in MCF-7 cells. by Mahvash Zakikhani (118421)

“…Loss of mitochondrial membrane potential (ΔΨ) is indicated by a decrease in FL2/FL1 fluorescence intensity ratio <b>(see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049513#pone.0049513.s001" target="_blank">Figure S1</a> for flow cytometry data set)</b>. …”

Fhl1b is essential for regulating the cell fate choice of liver versus pancreas and for β-cell regeneration. by Jin Xu (31283)

“…Decreased Fhl1b function leads to an increase in levels of <i>pdx1</i> expression in lateral 1 and 2 cells, causing a hepatic and pancreatic exocrine to a pancreatic endocrine fate switch. …”

Biomechanical effects of the abductor hip muscles local fatigue by Márcio Goethel (8995541)

“…When the volunteer failed to repeat the movements, the maximal voluntary isometric contraction of hip abduction was immediately tested using an isokinetic dynamometer Biodex System 4^®, in order to verify if there was a decrease of at least 50% in torque peak. Once fatigue observed, the volunteer was conducted to perform the tasks of squatting or drop landing, with no relevant resting period. …”

Expression of the ETS-5 target gene <i>gcy-9</i> restores CO₂-chemosensitivity to <i>ets-5</i> mutants. by Julia P. Brandt (176082)

“…Wild-type URX neurons (top panel) showed a small decrease in the ratio of YFP:CFP emissions in response to 10 s CO₂ pulses indicating decreases in cell calcium. …”

Monitoring intracellular K⁺ concentrations with GINKO2 in <i>E</i>. <i>coli</i> grown in K⁺-depleted media. by Sheng-Yi Wu (10887927)

“…<p>(A) <i>E</i>. <i>coli</i> are capable of accumulating K⁺ to a higher concentration than the environment. …”

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…<p><b>(A)</b> NKCC1 mRNA expression levels in newborn and adult microglia isolated from C57BL/6J mice compared to neural progenitors derived from E17 embryonic hippocampi. …”