MiR-106a aggravates sepsis-induced acute kidney injury by targeting THBS2 in mice model by Yezhou Shen (7291235)

“…LPS reduced cell viability and Bcl-2 expression, and increased caspase-3 activity, Bax expression, the content of TNF-α, IL-1β, IL-6. THBS2 was a target of miR-106a. The decreases of caspase-3 activity, TNF-α, IL-1β, IL-6, Bax expression and the increases of cell viability, Bcl-2 expression caused by miR-106a knockdown were reversed when THBS2 silencing in LPS-stimulated TCMK-1 cells. …”

Table_1_Assessing the genetic relationship between phimosis and 26 urogenital diseases: a Mendelian randomization study.xlsx by Wei Li (7081)

“…</p>Material and method<p>A dual-sample Mendelian randomization (MR) analysis was conducted using the publicly available genome-wide association study (GWAS) data. …”

Data_Sheet_2_Sphingomyelin and Medullary Sponge Kidney Disease: A Biological Link Identified by Omics Approach.PDF by Simona Granata (477257)

“…<p>Background: Molecular biology has recently added new insights into the comprehension of the physiopathology of the medullary sponge kidney disease (MSK), a rare kidney malformation featuring nephrocalcinosis and recurrent renal stones. …”

DataSheet2_Effect of type 2 diabetes on biochemical markers of bone metabolism: a meta-analysis.XLSX by Jie Yang (121778)

“…</p>Conclusion<p>In individuals with T2DM, most bone turnover markers indicated a reduced rate of bone turnover. This reduction can lead to increased bone fragility despite higher bone mineral density, potentially increasing the risk of osteoporosis.…”

What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting? by Rafael Freitas (16738416)

“…In the Tremendão area, which had the highest density (~555 stations per km²), the Ovitrap Positivity Index (OPI) decreased from 56.9% to 31.5%, while the average number of eggs per positive paddle dropped from 41.2 to 18.1—representing a 56% reduction in egg counts. …”

Data_Sheet_1_Reference Interval for Pulse Oxygen Saturation in Neonates at Different Altitudes: A Systematic Review.docx by Bo Wang (86769)

Are Environmental Levels of Nonsteroidal Anti-Inflammatory Drugs a Reason for Concern? Chronic Life-Cycle Effects of Naproxen in Zebrafish by Susana Barros (586042)

“…An integration of apical endpoints, i.e., survival, growth, and reproduction, with gonad histopathology and gene transcription (RNA-seq) was performed to provide additional insights into the mode of action (MoA) of NPX. NPX decreased zebrafish growth and reproduction and led to histopathological alterations in gonads at concentrations as low as 0.1 μg/L. …”

Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers by Daniel Nettersheim (2866097)

“…<p dir="ltr">In germ cell tumors (GCT), a growing teratoma during chemotherapy with decreasing tumor markers was defined as ´growing teratoma syndrome` (GTS) by Logothetis et al. in 1982. …”

Supplemental Figure 4 FIP1C is a negative modulator of Akt and MAPK activation in an ErbB2-driven model from Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary... by Pierre-Luc Boulay (14924160)

Table3_Efficacy of propofol for the prevention of emergence agitation after sevoflurane anaesthesia in children: A meta-analysis.docx by Yinggang Xiao (13896222)

“…</p>Discussion<p>We confirmed that a prophylactic dose of propofol prevented EA and decreased its severity in children under sevoflurane anesthesia. …”

Table3_Transcriptomics reveals a distinct metabolic profile in T cells from severe allergic asthmatic patients.xlsx by Carmela Pablo-Torres (10192451)

“…Severe allergic asthmatic patients presented downregulation in genes related to oxidative phosphorylation, fatty acid oxidation and glycolysis together with increased expression of genes coding inflammatory cytokines (e.g. IL-19, IL-23A and IL-31). Moreover, the downregulation of genes involved in TGFβ pathway together with a decreased tendency on the percentage of T regulatory cell (CD4 + CD25+), suggest a compromised regulatory function in severe allergic asthmatic patients. …”

Table_1_Tipping point of plant functional traits of Leymus chinensis to nitrogen addition in a temperate grassland.DOCX by Guojiao Yang (12158151)

“…We chose the native, perennial clonal grass, Leymus chinensis in Inner Mongolia steppe, and conducted a field experiment, in which six N addition rates (0, 2, 5, 10, 20, and 50 g N m^–2 year^–1) and five N compound types [NH₄NO₃, (NH₄)₂SO₄, NH₄HCO₃, CO(NH₂)₂, slow-release CO(NH₂)₂] are considered. …”

Image7_Efficacy of propofol for the prevention of emergence agitation after sevoflurane anaesthesia in children: A meta-analysis.tif by Yinggang Xiao (13896222)

“…</p>Discussion<p>We confirmed that a prophylactic dose of propofol prevented EA and decreased its severity in children under sevoflurane anesthesia. …”

Image_2_Causality between Ankylosing Spondylitis and osteoarthritis in European ancestry: a bidirectional Mendelian randomization study.tif by Yangguang Lu (17906228)

“…MR results revealed that individuals with AS exhibit a decreased risk of knee OA (OR = 0.9882, 95% CI: 0.9804-0.9962) but no significant increase in the risk of hip OA (OR = 0.9901, 95% CI: 0.9786-1.0018). …”

Table_1_Preoperative Transcranial Direct Current Stimulation in Glioma Patients: A Proof of Concept Pilot Study.DOCX by Stefan Lang (389771)

“…Voxel-wide measures, not constrained by a specific region, revealed increased global connectivity of the frontal pole and decreased global connectivity of the supplementary motor area. …”

DataSheet_1_cleanSURFACES® intervention reduces microbial activity on surfaces in a senior care facility.docx by Justin R. Wright (5582006)

“…To that end, this study utilized a metatranscriptomic sequencing workflow (CSI-Dx™) to profile active microbial communities from surfaces in the HJ Heinz Community Living Center, a long-term care facility in the Veterans Affairs Pittsburgh Health Care System. …”

DataSheet1_The Efficacy and Safety of Brolucizumab for the Treatment of nAMD: A Systematic Review and Meta-Analysis.pdf by Junlan Chuan (6648617)

“…</p><p>Results: A total of six RCTs with 3,574 participants were finally involved in this meta-analysis. …”

Supplementary Material for: Swallowed topical tacrolimus induces clinical and histological remission in a subset of patients with severe lymphocytic esophagitis by Schoepfer A. (9540059)

“…Introduction: Lymphocytic esophagitis (LyE) represents a chronic inflammatory disease of the esophagus with low response rates to topical steroids. …”

Table_1_Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach.docx by Rebecca Ingelfinger (9341330)

“…Here, we explored the pharmacological activity of six lichen extracts (Evernia prunastri, Pseudevernia furfuracea, Umbilicaria pustulata, Umbilicaria crustulosa, Flavoparmelia caperata, Platismatia glauca) in the context of cancer and inflammation using a comprehensive set of 11 functional and biochemical in vitro screening assays. …”

Table 6_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Background<p>Osteomyelitis, a persistent inflammatory bone disease, is only partially responsive to conventional antibiotics and surgery. …”