GABA_A receptor-expressing neurons promote consumption in <i>Drosophila melanogaster</i> by Samantha K. Cheung (3897748)

“…Acute activation of these neurons is sufficient to drive consumption of appetitive substances and non-appetitive substances and acute silencing of these neurons decreases consumption. Taken together, these studies identify GABA_A receptor-expressing neurons that promote <i>Drosophila</i> ingestive behavior and provide insight into feeding regulation.…”

Reducing age bias in decision analyses of anticoagulation for patients with nonvalvular atrial fibrillation – A microsimulation study by Matthew A. Pappas (5504363)

“…<div><p>Background</p><p>Anticoagulation decreases a patient’s risk of ischemic stroke and increases the risk of hemorrhage. …”

Drug-induced decrease of cell anisotropy reduces pattern fidelity. by Camille Curantz (7456499)

“…<b>(B)</b> Quantifications of primordia spacing variability on phalloïdin-stained control flat skins (explant; triangles) and LatA-treated cultured explants (+LatA; squares) of Japanese quail embryos showed that LatA treatment caused a significant decrease in pattern fidelity at condensation stage (explants, <i>n</i> = 9; +LatA, <i>n</i> = 9; unpaired 2-tailed <i>t</i> test; <i>p</i> = 0.0233) and differentiation stage (explants, <i>n</i> = 8; +LatA, <i>n</i> = 9; <i>p</i> = 0.002). …”

Parametric Analysis of Gene Set Enrichment identifies Gene Ontology (GO) terms changed in gastrocnemius muscle of 13-month old D257A mice as compared to 13-month old WT mice. by Asimina Hiona (246175)

“…(D) Genes listed within the GO term “electron transport chain” (<i>Z</i>-score = −8.89; p<0.0001) whose expression level significantly (p<0.01) increased (yellow) or decreased (blue) in D257A mice.</p>…”

Table_2_A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins.pdf by Kaveh Emami (320085)

“…Two of the three mutant proteins purified showed decreased sensitivity to IQC in vitro. Finally, inhibition by IQC was rescued by addition of cytidine but not uridine to the growth medium, consistent with the notion that IQC acts by reducing the synthesis of CTP or a related compound. …”

Table_1_A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins.pdf by Kaveh Emami (320085)

“…Two of the three mutant proteins purified showed decreased sensitivity to IQC in vitro. Finally, inhibition by IQC was rescued by addition of cytidine but not uridine to the growth medium, consistent with the notion that IQC acts by reducing the synthesis of CTP or a related compound. …”

Skin-resident macrophages decrease in number before the onset of anagen. by Donatello Castellana (678749)

“…(D) Fluctuations in the number of perifollicular macrophages during the second hair cycle analyzed by immunofluorescence. Note the decrease in F4/80⁺ at A_VI. Each histogram point represents the mean value of positive cells per 10× magnification field at 30 µm distance from HF <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002002#pbio.1002002-Paus1" target="_blank">[15]</a>. 10 fields/section/mouse were analyzed; <i>n</i> = 4. …”

Image_1_A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins.tif by Kaveh Emami (320085)

“…Two of the three mutant proteins purified showed decreased sensitivity to IQC in vitro. Finally, inhibition by IQC was rescued by addition of cytidine but not uridine to the growth medium, consistent with the notion that IQC acts by reducing the synthesis of CTP or a related compound. …”

Image_2_A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins.tif by Kaveh Emami (320085)

“…Two of the three mutant proteins purified showed decreased sensitivity to IQC in vitro. Finally, inhibition by IQC was rescued by addition of cytidine but not uridine to the growth medium, consistent with the notion that IQC acts by reducing the synthesis of CTP or a related compound. …”

Image_3_A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins.tif by Kaveh Emami (320085)

“…Two of the three mutant proteins purified showed decreased sensitivity to IQC in vitro. Finally, inhibition by IQC was rescued by addition of cytidine but not uridine to the growth medium, consistent with the notion that IQC acts by reducing the synthesis of CTP or a related compound. …”

Image_4_A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins.tif by Kaveh Emami (320085)

“…Two of the three mutant proteins purified showed decreased sensitivity to IQC in vitro. Finally, inhibition by IQC was rescued by addition of cytidine but not uridine to the growth medium, consistent with the notion that IQC acts by reducing the synthesis of CTP or a related compound. …”

Data_Sheet_1_Functional Division Between the RecA1 and RecA2 Proteins in Myxococcus xanthus.pdf by Duo-Hong Sheng (8441805)

“…Deletion of recA1 did not affect the growth but significantly decreased the UV-radiation survival, homologous recombination (HR) ability, and induction of LexA-dependent SOS genes. …”

Data_Sheet_2_Functional Division Between the RecA1 and RecA2 Proteins in Myxococcus xanthus.pdf by Duo-Hong Sheng (8441805)

“…Deletion of recA1 did not affect the growth but significantly decreased the UV-radiation survival, homologous recombination (HR) ability, and induction of LexA-dependent SOS genes. …”

(<i>S</i>)-PZQ decrease tone of contracted mesenteric arteries. by Gihan S. Gunaratne (5117795)

Meningococcal adhesion on endothelial cells is required to decrease EPCR expression. by Hervé Lécuyer (5076971)

Dex treatment results in a change in cell shape, actin organization and pFAK localization. by Stephen Shannon (784424)

The Attenuation of Diabetic Nephropathy by Annexin A1 via Regulation of Lipid Metabolism through AMPK/PPARα/CPT1b Pathway by Liang Wu (131111)

“…Inflammation and abnormal metabolism play important roles in the pathogenesis of diabetic nephropathy (DN). Annexin A1 (ANXA1) contributes to inflammation resolution and improves metabolism. …”

Data_Sheet_1_Secretory Vesicle and Glucoamylase Distribution in Aspergillus niger and Macromorphology in Regions of Varying Shear Stress.PDF by Philipp Kunz (11922170)

“…Quantitative analysis of the time course suggests that the amount of available secretory vesicles inside of A. niger decreases when the shear stress is increased, despite that no significant differences in biomass production could be found. …”

Prevention of lysosomal degradation by bafilomycin A1 enhanced the amount of LC3-II and the appearance of a punctuate LC3 pattern in chondrocytes co-treated with TNF-α and DRB. by Sung Won Lee (222509)

“…Bafilomycin A1 significantly decreased the cells having LysoTracker-positive vacuoles (** <i>P</i><0.01). …”

Data_Sheet_1_Effect of the Monothiol Glutaredoxin GrxD on 2,4-Diacetylphloroglucinol Biosynthesis and Biocontrol Activity of Pseudomonas fluorescens 2P24.doc by Qiuling Dong (13016559)

“…<p>Pseudomonas fluorescens 2P24 is a plant root-associated bacterium that suppresses several soilborne plant diseases due to its production of the antibiotic 2,4-diacetylphloroglucinol (2,4-DAPG). …”