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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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21741
Image1_Apol9a regulates myogenic differentiation via the ERK1/2 pathway in C2C12 cells.TIF
Published 2022“…</p><p>Results: RNA-seq of differentiated and undifferentiated C2C12 cells revealed that Apol9a expression significantly increased following myogenic differentiation and decreased during obesity-induced muscle atrophy. …”
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21742
Changes in deneddylase activity and its consequences for the cellular pool of neddylated proteins and fungal development.
Published 2016“…Wild type (WT) was compared to mutant strains with altered deneddylase activity either with decreased COP9 signalosome (Δ<i>csnG</i>, Δ<i>csnE</i>) or increased <i>denA</i> (OE <i>denA</i>) and combinations of defective CSN and increased DenA (Δ<i>csnG</i>/OE <i>denA</i>, or Δ<i>csnE</i>/OE <i>denA</i>). …”
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21743
Image1_The L1624Q Variant in SCN1A Causes Familial Epilepsy Through a Mixed Gain and Loss of Channel Function.JPEG
Published 2021“…Using patch-clamp to characterize channel properties at several temperatures, we show that the L1624Q variant increases persistent current, accelerates fast inactivation onset and decreases current density. While SCN1A-associated epilepsy is typically considered a loss-of-function disease, our results put L1624Q into a growing set of mixed gain and loss-of-function variants in SCN1A responsible for epilepsy.…”
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21744
DataSheet_1_TaSPL14-7A is a conserved regulator controlling plant architecture and yield traits in common wheat (Triticum aestivum L.).pdf
Published 2023“…Overexpression of TaSPL14-7A in wheat resulted in significant changes in plant architecture and yield traits, including decreased tiller number and increased kernel size and weight. …”
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21745
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21746
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21747
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21748
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21749
Hypoxia-induced increase in STAT5A substrate phosphorylation by prostate carcinoma cells.
Published 2013“…<p>(A) 22Rv1 cells were exposed to moderate (1% O<sub>2</sub>) and severe (<0.02% O<sub>2</sub>) hypoxia for 24 hours in a hypoxia chamber. …”
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21750
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21751
Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc...
Published 2024“…<p>Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by the deposition of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. …”
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21752
Table_1_Annexin A12–26 Treatment Improves Skin Heterologous Transplantation by Modulating Inflammation and Angiogenesis Processes.pdf
Published 2018“…It has been shown that N-terminal portion of the Annexin A1 protein (AnxA1) with its anti-inflammatory properties induces epithelial mucosa repair and presents potential therapeutic approaches. …”
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21753
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21754
Regiospecifically Fluorinated Polycyclic Aromatic Hydrocarbons via Julia–Kocienski Olefination and Oxidative Photocyclization. Effect of Fluorine Atom Substitution on Molecular Sha...
Published 2016“…The fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanarity in the benzo[<i>c</i>]phenanthrene derivatives, but its influence was most pronounced in the benzo[<i>g</i>]chrysene series. …”
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21755
The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels
Published 2015“…In addition, we measured mRNA levels of a known miR-34a target, HNF4A, and found the HNF4A levels to be decreased in ccRCC tumors, but unexpectedly correlated positively rather than negatively with miR-34a.…”
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21756
Table_1_Screening of Antiviral Components of Ma Huang Tang and Investigation on the Ephedra Alkaloids Efficacy on Influenza Virus Type A.docx
Published 2019“…<p>Although Ma Huang Tang (MHT) has long been considered as a classical formula for respiratory infections like influenza, bronchitis and asthma, its chemical ingredients that really exert the main efficacy are still obscure. …”
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21757
DataSheet1_SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids.docx
Published 2024“…This finding together with the observation that UA absorption is increased in organoids with SLC2A9 overexpression and decreased in those with SLC2A9 knockdown, suggest that GLUT9 is responsible for UA absorption, and the rs16890979 SNP may compromise this functionality. …”
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21758
DataSheet3_Antioxidant and Anti-Inflammatory Properties of Hydroxyl Safflower Yellow a in Diabetic Nephropathy: A Meta-Analysis of Randomized Controlled Trials.pdf
Published 2022“…<p>Background: Diabetic kidney disease (DKD) is a chronic progressive disorder which is a leading cause of chronic kidney disease (CKD). …”
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21759
DataSheet5_Antioxidant and Anti-Inflammatory Properties of Hydroxyl Safflower Yellow a in Diabetic Nephropathy: A Meta-Analysis of Randomized Controlled Trials.pdf
Published 2022“…<p>Background: Diabetic kidney disease (DKD) is a chronic progressive disorder which is a leading cause of chronic kidney disease (CKD). …”
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21760
DataSheet7_Antioxidant and Anti-Inflammatory Properties of Hydroxyl Safflower Yellow a in Diabetic Nephropathy: A Meta-Analysis of Randomized Controlled Trials.pdf
Published 2022“…<p>Background: Diabetic kidney disease (DKD) is a chronic progressive disorder which is a leading cause of chronic kidney disease (CKD). …”