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223881
Table1_Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.XLSX
Published 2022“…</p><p>Conclusion: This study demonstrated the functional role of the ARS/miR-29b-3p/HMCN1 axis in alleviating myocardial I/R injury, which provided a new direction for myocardial I/R injury therapy.…”
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223882
Table_7_Characterization of the gene expression profile response to drought stress in Haloxylon using PacBio single-molecule real-time and Illumina sequencing.XLSX
Published 2022“…Thisis the first full-length transcriptome report concerning the responses of H. ammodendron and H. persicum to drought stress. The results provide a foundation for further study of the adaptation to drought stress. …”
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223883
Data_Sheet_1_Role of LATS1/2 in Prognosis of Advanced Gastric Cancer and Its Relationship With the Tumor Immune Microenvironment.docx
Published 2020“…<p>Background: Gastric cancer (GC) remains a refractory cancer particularly in Eastern Asia. …”
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223884
Bacterial cellulose nanocrystals: from obtaining, under different hydrolysis conditions, the incorporation as reinforcement in poly(L-lactic acid)
Published 2018“…<p></p><p>ABSTRACT This work aimed to produce bacterial cellulose, to obtain bacterial cellulose nanocrystals, to incorporate nanocrystals as a reinforcement in poly(L-lactic acid) and to evaluate the properties of these bionanocomposites. …”
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223885
Gal-3 knockdown sensitizes cells to cell death in oxygen and nutrient deprivation in the NG97ht cell line.
Published 2014“…<p>Analysis of NG97ht cells incubated with specific gal-3 siRNA or scramble siRNA for 6 h and then exposed to either normoxia (N), CoCl<sub>2</sub> (C) or hypoxia (H) in complete or serum-deprived medium for additional 42 h. <b><i>A</i></b>. Protein analysis demonstrated gal-3 knockdown in each experimental condition. …”
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223886
DataSheet8_Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway.XLSX
Published 2021“…The combination of network pharmacology approaches with experimental validation may offer a useful tool to characterize the molecular mechanism of multicomponent complexes.…”
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223887
Data_Sheet_1_Response of Resistance Exercise-Induced Muscle Protein Synthesis and Skeletal Muscle Hypertrophy Are Not Enhanced After Disuse Muscle Atrophy in Rat.docx
Published 2020“…Thirty male Sprague-Dawley rats were randomly divided into control (CON) or hindlimb suspension (HS) groups. A 14-day HS via the tail was used as the model for gastrocnemius muscle disuse in the HS group. …”
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223888
DataSheet_1_GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis.pdf
Published 2022“…Moreover, compared with WT mice, GSDMD<sup>-/-</sup> mice showed reduced infarct size (25.45 ± 3.07% versus 36.47 ± 3.72%), improved left ventricular ejection fraction (37.71 ± 1.81% versus 29.44 ± 2.28%) and left ventricular fractional shortening (18.01 ± 0.97% versus 13.62 ± 1.15%) as well as attenuated pathological damage after I/R injury, along with reduced levels of proinflammatory cytokines and decreased infiltration of neutrophils.</p>Conclusions<p>Our study revealed that GSDMD deficiency significantly alleviated the inflammatory response by regulating pyroptosis, reduced the infarct size and preserved cardiac function after MI/RI, thus providing a potential strategy for the treatment of myocardial reperfusion injury.…”
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223889
Image1_2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.jpg
Published 2022“…The main purpose of this study was to investigate the protective effect of THSG against bleomycin (BLM)-induced lung fibrosis in a murine model, and explore the underlying mechanisms of THSG in transforming growth factor-beta 1 (TGF-β1)-induced fibrogenesis using MRC-5 human lung fibroblast cells. …”
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223890
DataSheet1_Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice.docx
Published 2022“…</p><p>Conclusion: GSDMD-mediated pyroptosis is involved in the mechanism of kainic acid-induced seizures. Our study provides a new potential therapeutic target for seizure control.…”
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223891
Effects of BmCPV Infection on Silkworm <i>Bombyx mori</i> Intestinal Bacteria
Published 2016“…<div><p>The gut microbiota has a crucial role in the growth, development and environmental adaptation in the host insect. …”
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223892
COMPARISON OF IMPLANT DENSITY IN THE MANAGEMENT OF LENKE 1B AND 1C ADOLESCENT IDIOPATHIC SCOLIOSIS
Published 2019“…The HD group had higher blood loss (p =.02), number of implants (p <.001), levels fused (p =.002), and surgical time (p <.001). The HD group had a higher prevalence of hypokyphosis from before operation to follow-up (p <.001). …”
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223893
Kinetics of alpaca innate immune responses at the nasal submucosa in response to MERS-CoV Qatar15/2015.
Published 2021“…<p>(A) The nasal submucosa of each alpaca (AP1, 2, 3, 7, 8, 9, 13, 14 and 15) was micro-dissected and areas underlying infected (orange)/non-infected (green) epithelium, as assessed by IHC (see the right panel), were selected and isolated for RNA extraction and conversion to cDNA. …”
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223894
DataSheet_1_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.pdf
Published 2022“…Notably, 5 optimal ASV-based microbial markers were identified as the diagnostic model of AL amyloidosis and the AUC value of the train set and the test set was 0.8549 (95% CI 0.7310-0.9789) and 0.8025 (95% CI 0.5771-1), respectively. With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”
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223895
DataSheet_3_Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction...
Published 2021“…We confirmed this mechanistic effect in a CLP-induced sepsis model of intestinal SIRT3 conditional-knockout mice, and found that melatonin preserved mitochondrial function and induced autophagy of small-intestine epithelial cells; these effects were dependent on SIRT3 activation. …”
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223896
Data_Sheet_1_Ramadan Fasting Leads to Shifts in Human Gut Microbiota Structured by Dietary Composition.pdf
Published 2021“…Principal Coordinate Analyses (PCoA) comparison of samples collected from both groups before and after fasting showed partial separation of microbiota related to fasting in the Pakistani group, but not in the Chinese group. …”
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223897
Table_4_Comprehensive Analysis of Long Non-coding RNA Modulates Axillary Bud Development in Tobacco (Nicotiana tabacum L.).XLSX
Published 2022“…By lncRNA transcriptomes of axillary buds in topped and untopped tobacco plants, we identified a total of 13,694 lncRNAs. LncRNA analysis indicated that the promoted growth of axillary bud by topping might be partially ascribed to the genes related to hormone signal transduction and glycometabolism, trans-regulated by differentially expressed lncRNAs, such as MSTRG.52498.1, MSTRG.60026.1, MSTRG.17770.1, and MSTRG.32431.1. …”
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223898
Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells
Published 2017“…To further understand the role of epigenetic mechanism in enhanced chemotherapeutic efficacy by estrogen, cells were pre-treated with epigenetic drugs, 5-aza-2-deoxycytidine and Trichostatin A prior to doxorubicin and cisplatin treatments. …”
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223899
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223900