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largest decrease » largest decreases (توسيع البحث), larger decrease (توسيع البحث), marked decrease (توسيع البحث)
greater decrease » greater increase (توسيع البحث), greater increases (توسيع البحث), rate decreased (توسيع البحث)
linear decrease » linear increase (توسيع البحث)
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224421
DataSheet1_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF
منشور في 2025"…<p>A previously identified anti-rheumatic compound α-mangostin (MAN) possesses notable metabolism regulatory properties. …"
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224422
Data_Sheet_1_Intraocular complement activation is related to retinal vascular and neuronal degeneration in myopic retinopathy.docx
منشور في 2023"…The levels of complement proteins including C1q, C3, C3b/iC3b, C4, CFB, CFH, C2, C4b, C5, C5a, CFD, MBL and CFI in the aqueous humour were measured using the Luminex Multiplexing system. …"
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224423
Downregulation of cancer-associated fibroblast exosome-derived miR-29b-1-5p restrains vasculogenic mimicry and apoptosis while accelerating migration and invasion of gastric cancer...
منشور في 2023"…<p><b>Background:</b> Cancer-associated fibroblast (CAF) exosomal miRNAs have gradually a hot spot in cancer therapy. This study mainly explores the effect of CAF-derived exosomal miR-29b-1-5p on gastric cancer (GC) cells.…"
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224424
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224425
Proposed model for extracellular/intracellular Gal-9 <i>trans</i> and <i>cis</i> association with Tim-3 in regulation of monocyte inflammatory cytokine expressions through TLR sign...
منشور في 2013"…Intracellular Gal-9 also inhibits STAT3 but not STAT-1 phosphorylation, leading to increased IL-12 and decreased IL-23 gene transcriptions. However, intracellular Gal-9 appears to reduce Tim-3 cell surface expression by two distinct mechanisms: <i>cis</i> association/internalization and transcriptional inhibition, through a STAT-3-independent but possibly T-bet-dependent pathway (10). …"
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224426
Twsg1 null mice were resistant to podocyte injury.
منشور في 2014"…<p>(<b>A</b>) Twsg1<sup>+/+</sup>:NEP25 and Twsg1<sup>LacZ/LacZ</sup>:NEP25 mice were injected with immunotoxin and analyzed seven days later. …"
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224427
Initial assessment of βHB treatment effects.
منشور في 2024"…<p>A) In experiment 1, body weight was reduced on day 1 after ICH (day 1, p<0.0001), and the βHB group weighed more than the VEH group on day 1 (p = 0.0250). …"
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224428
Presentation_1_Effect of Pelvic Bone Marrow Sparing Intensity Modulated Radiation Therapy on Acute Hematologic Toxicity in Rectal Cancer Patients Undergoing Chemo-Radiotherapy.pptx
منشور في 2021"…The patients treated with PBM sparing IMRT had a lower incidence of acute HT compared with those treated with non-PBM sparing IMRT. …"
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224429
Image_2_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg
منشور في 2024"…This study sought to investigate the involvement of γδ T cells and its subsets in placental Plasmodium falciparum malaria.</p>Methods<p>In a case-control study conducted in Yaoundé, Cameroon from March 2022 to May 2023, peripheral, placental and cord blood samples were collected from 50 women at delivery (29 PM negative: PM- and 21 PM positive: PM+; as diagnosed by light microscopy). …"
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224430
Image_3_Postoperative Long-Term Independence Among the Elderly With Meningiomas: Function Evolution, Determinant Identification, and Prediction Model Development.tif
منشور في 2021"…We used univariate and multivariate analyses to determine the risk factors for postoperative long-term independence, and nomogram was established.</p>Results<p>A total of 470 patients were included eligibly. …"
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224431
Image_4_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif
منشور في 2021"…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …"
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224432
Image_9_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg
منشور في 2024"…This study sought to investigate the involvement of γδ T cells and its subsets in placental Plasmodium falciparum malaria.</p>Methods<p>In a case-control study conducted in Yaoundé, Cameroon from March 2022 to May 2023, peripheral, placental and cord blood samples were collected from 50 women at delivery (29 PM negative: PM- and 21 PM positive: PM+; as diagnosed by light microscopy). …"
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224433
Image_2_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif
منشور في 2021"…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …"
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224434
Image_2_Gender- and Age-Associated Differences in Bone Marrow Adipose Tissue and Bone Marrow Fat Unsaturation Throughout the Skeleton, Quantified Using Chemical Shift Encoding-Base...
منشور في 2022"…<p>Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with osteoporosis, bone metastasis, and primary bone tumors. …"
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224435
DataSheet_1_TLR2/TLR4-Enhanced TIPE2 Expression Is Involved in Post-Hemorrhagic Shock Mesenteric Lymph-Induced Activation of CD4+T Cells.doc
منشور في 2022"…</p>Conclusion<p>TIPE2 improves the PHSML-mediated CD4<sup>+</sup>T cells dysfunction by regulating TLR2/TLR4 pathway, providing a new intervention target following hemorrhagic shock-induced immune dysfunction.…"
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224436
γδ T cells have similar TCR threshold but enhanced ERK1/2 phosphorylation comparing to αβ T cells.
منشور في 2013"…<p>(A) Percentages of BrdU<sup>+</sup> proliferative cells are higher in the γδ T cell subset <i>in vivo</i>. …"
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224437
Data_Sheet_1_City-level meteorological conditions modify the relationships between exposure to multiple air pollutants and the risk of pediatric hand, foot, and mouth disease in th...
منشور في 2023"…</p>Methods<p>For each of the 17 cities in the Sichuan Basin, we obtained estimates of the relationship between exposures to multiple air pollutants and childhood HFMD risk by using a unified distributed lag nonlinear model (DLNM). …"
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224438
Data_Sheet_1_Anti-hyperuricemic and Anti-inflammatory Effects of Marantodes pumilum as Potential Treatment for Gout.docx
منشور في 2020"…The anti-hyperuricemic activity was initially assessed by XO inhibition with a spectrophotometric in vitro assay. The most active extract was further investigated on hyperuricemic rat model induced by potassium oxonate to determine serum uric acid levels and liver XO effect. …"
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224439
<i>Hirsutella sinensis</i> Attenuates Aristolochic Acid-Induced Renal Tubular Epithelial-Mesenchymal Transition by Inhibiting TGF-β1 and Snail Expression
منشور في 2016"…These results suggest Snail might be a potential target of HS effect.</p><p>Conclusion</p><p>HS is able to antagonize, to some extent, tubular EMT and renal interstitial fibrosis caused by AA, which might be related to its inhibitory effects on the TGF-β1 and Snail expression.…"
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224440
DataSheet_1_Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activat...
منشور في 2023"…Recent studies have indicated that microRNA-222-3p (miR-222-3p) is increased in colon of UC and colorectal cancer (CRC) patients, and miR-222-3p is a crucial regulator of oxidative stress. However, whether miR-222-3p influences IEC oxidative stress in UC and CAC remains unknown. …"