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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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27601
DataSheet_1_RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mou...
Published 2022“…Gene expression analysis demonstrated that Ref-1 inhibitors significantly decreased IL-8, FOSB, and c-Jun when functional RelA is present. …”
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27602
Data_Sheet_1_Non-canonical Interaction Between O-Linked N-Acetylglucosamine Transferase and miR-146a-5p Aggravates High Glucose-Induced Endothelial Inflammation.PDF
Published 2020“…Real time PCR analysis found that miR-146a-5p was decreased in HG- and glucosamine-stimulated HAECs. …”
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27603
Serum LRG levels in patients with DM-IP and the HC, and changes in serum LRG levels at baseline measurement and at 2, 4, and 8 weeks after the initiation of treatment.
Published 2020“…<p>The serum LRG levels of the DM-IP patients were higher than those of the HC (A). The serum LRG levels at 2, 4, and 8 weeks after the initiation of treatment were significantly decreased in comparison with those before treatment (B). …”
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27604
Future ozone-related acute excess mortality under climate and population change scenarios in China: A modeling study
Published 2018“…Future ozone-related acute excess mortality from cardiovascular diseases was 5–8 times greater than that from respiratory diseases. Ozone concentrations increase by 15.1 parts per billion (10<sup>−9</sup>) in colder months (November to April), contributing to a net yearly increase of 22.3% (95% eCI: 7.7% to 35.4%) in ozone-related mortality under RCP8.5. …”
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27605
C-terminal regions are required for interaction.
Published 2010“…Deletion of the C-terminal of RipA decreased the intensity of interaction and the C-terminal 25 amino acids of RipA were sufficient for interaction with PBP1. …”
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27606
Empirical Bayesian Random Censoring Threshold Model Improves Detection of Differentially Abundant Proteins
Published 2014“…A challenge in proteomics is that many observations are missing with the probability of missingness increasing as abundance decreases. …”
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27607
Synthesis and Molecular Structure of Gold Triarylcorroles
Published 2011“…A number of third-row transition-metal corroles have remained elusive as synthetic targets until now, notably osmium, platinum, and gold corroles. …”
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27608
Volcano plots of whole body, plasma and hepatic features in the blockade arm, including the RD, WDD, WDB and WDO Groups.
Published 2017“…The Pie Plots <b>[D]</b> represent a summary of the features that increased, decreased or did not change with diet treatment in each comparison.…”
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27609
Quantitative RT-qPCR demonstrate that Tat complex modulates expression of C5, CRLF2, APBA1, and BDNF.
Published 2017“…Significance was determined using a Wilcoxon signed-rank test. Error bars represent the median ± S.D.; **P < 0.01.…”
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27610
DataSheet_1_A20 Inhibits Intraocular Inflammation in Mice by Regulating the Function of CD4+T Cells and RPE Cells.docx
Published 2021“…A decreased expression of A20 in CD4+T cells was noticed in active BD patients but not in VKH patients. …”
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27611
Data_Sheet_1_Adherence of Lactobacillus salivarius to HeLa Cells Promotes Changes in the Expression of the Genes Involved in Biosynthesis of Their Ligands.PDF
Published 2020“…<p>The attachment of a variety of Lactobacilli to the mucosal surfaces is accomplished through the interaction of OppA, a superficial bacterial protein also involved in oligopeptide internalization, and the glycosaminoglycan moiety of the proteoglycans that form the epithelial cell glycocalyx. …”
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27612
Modulation of Zn–C Bond Lengths Induced by Ligand Architecture in Zinc Carbatrane Compounds
Published 2016“…It is, therefore, significant that we have demonstrated that the incorporation of appropriately sized linkers between carbon and a metal center provides a means to modulate the length and nature of a metal–carbon interaction. …”
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27613
Volcano plots of whole body, plasma and hepatic features in the blockade arm, including the RD, WDB and WDO groups.
Published 2017“…The Pie Plots <b>[D]</b> represent a summary of the features that increased, decreased or did not change with diet treatment in each comparison.…”
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27614
Depletion of PBP1 blocks cell division.
Published 2010“…OriE: <i>E. coli</i> origin of replication. (B) PBP1 (<i>ponA1</i>) depletion strain of <i>M. smegmatis</i> was grown with inducer (ATC = anhydrotetracycline), then inoculated into media with decreasing amounts of inducer and followed by OD<sub>600</sub> over time. …”
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27615
Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers
Published 2019“…We found that the cell lines that were HMGA2-positive and/or HOXC9-negative have a reduced sensitivity to retinoids. Furthermore, the experiments revealed that the retinoid-sensitive cell lines showed a uniform pattern of change after treatment with both natural and sensitive retinoids: increased DDX39A and decreased PBX1 protein levels. …”
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27616
DataSheet_1_Integrative analysis of mitochondrial metabolic reprogramming in early-stage colon and liver cancer.pdf
Published 2023“…Using a genome-scale metabolic model, we demonstrated that HMGCS2 suppression increased glycolysis, lipid biosynthesis, and elongation while decreasing fatty acid oxidation in colon cancer cells. …”
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27617
Presentation_1_The Autoimmune Disorder Susceptibility Gene CLEC16A Restrains NK Cell Function in YTS NK Cell Line and Clec16a Knockout Mice.pdf
Published 2019“…We overexpressed CLEC16A in YTS natural killer (NK) cells and observed reduced NK cell cytotoxicity and IFN-γ release, delayed dendritic cell (DC) maturation, decreased conjugate formation, cell-surface receptor downregulation and increased autophagy. …”
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27618
Table_1_METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer.docx
Published 2021“…We found that the m<sup>6</sup>A methylated RNA was dramatically decreased in TNBC tissues and cell lines. …”
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27619
Endothelial Cells Can Regulate Smooth Muscle Cells in Contractile Phenotype through the miR-206/ARF6&NCX1/Exosome Axis
Published 2016“…Furthermore, a reduction of the miR-26a-containing exosomes secreted from HUVECs affects the SMC phenotype. …”
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27620
DataSheet_1_METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer.docx
Published 2021“…We found that the m<sup>6</sup>A methylated RNA was dramatically decreased in TNBC tissues and cell lines. …”