Fixing a heart valve by Nature Research (16552612)

“…Rheumatic fever and carditis are characterized by cardiac inflammation and scarring, which narrows the valves in the heart and restricts the flow of blood through them. These conditions are a major public health issue in many parts of the world, and in economically developed countries are usually treated by a surgical procedure to replace the damaged heart valve. …”

Identification of a sniffing signature. by Romain Fayat (22404831)

“…<p>(A) Upper panels: example traces of head gravitational acceleration (), non-gravitational acceleration (), and angular velocity (<b>ω</b>). …”

Inclisiran: A Review in Hypercholesterolemia by James E. Frampton (4995257)

“…</p> <p><br></p> <p>Additional information about this Adis Drug Review can be found <a href="http://www.springer.com/gp/adis/products-services/adis-journals-newsletters/adis-drug-reviews" target="_blank"><strong>here</strong></a></p> <p><br></p> <p><strong>Abstract</strong></p> <p>Inclisiran (Leqvio^®) is a first-in-class, subcutaneously administered, small interfering RNA (siRNA) that prevents hepatic synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9), thereby decreasing circulating low-density lipoprotein cholesterol (LDL-C). …”

ANOVA for vigor index A. by Ahad Asghari (20615202)

“…The results revealed that increasing PAW levels up to 0.18 min/mL led to an increase in seed germination percentage, seedling weight (both fresh and dry), seedling length, vigor indexes A and B, and water uptake and decreasing mean germination time. …”

Schematic diagram of a cross section of a receptive syconium of <i>Ficus obtusifolia</i>. by Ellen O. Martinson (757640)

A working model for PQT3 acting as a negative regulator of oxidative stress response. by Chao Luo (343569)

“…As a result, PQT3 activity is increased, leading to faster removal of PRMT4b via 26S proteasome. …”

A Randomized Clinical Trial Testing the Anti-Inflammatory Effects of Preemptive Inhaled Nitric Oxide in Human Liver Transplantation by John D. Lang Jr (522420)

“…ICU (p = 0.47) and hospital length of stay (p = 0.49) were not decreased. iNO increased concentrations of nitrate (p<0.001), nitrite (p<0.001) and nitrosylhemoglobin (p<0.001), with nitrite being postulated as a protective mechanism. …”

Transverse vibration and stability of a functionally graded rotating annular disk with a circumferential crack by Bahaloo, Hassan

“…The critical speed of these disks may be affected by the presence of defects such as a circumferential crack. In this paper out of plane vibration of functionally graded (FG) rotating annular disks with a circumferential open crack is investigated. …”
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Video_1_PET/CT imaging detects intestinal inflammation in a mouse model of doxorubicin-induced mucositis.wmv by Sina Dalby (14262449)

“…Introduction<p>A severe side effect of cancer chemotherapy is the development of gastrointestinal mucositis, characterised by mucosal inflammation. …”

Dynamics of a parabolic 2-D cluster with cells secreting a single growth inhibitor. by Yipei Guo (11663432)

“…<p>(a) We treat <i>X</i> as a growth inhibitor (as indicated by the elliptical arrowhead), such that cells can only grow if the concentration of <i>X</i> is below a threshold i.e. . …”

GSTM3 A/B Polymorphism and Risk for Head and Neck Cancer: A Meta-Analysis by Yu Xu (52257)

“…</p><p>Results</p><p>Fourteen studies from ten publications with 2110 patients and 2259 controls were included. Overall, the GSTM3 A/B polymorphism was associated with a decreased risk of HNC using the dominant model, homozygote comparison model and heterozygote comparison model (OR = 0.82, 95%CI: 0.71–0.94; OR = 0.67, 95%CI: 0.49–0.94; and OR = 0.84, 95%CI: 0.73–0.97, respectively); besides, in stratification analyses by ethnicity, similar results were observed in Caucasian populations. …”

Course of T_body of a female pup before, during and after a thunderstorm. by Nicola Erdsack (443390)

“…Pup had been sleeping in the sun for 1.5 hours. <b>5:20 p.m.</b>: A thunderstorm with strong rain started and lasted for 28 minutes. …”

A Long-Term Macroecological Analysis of the Recovery of a Waterbird Metacommunity after Site Protection by Janina Pagel (617287)

“…Non-random selective extinction was the most likely historical process creating the nested pattern, operated by the differential carrying capacity (surface-area) of the remaining sites. We also found a positive temporal trend in nestedness and a decreasing trend in species turnover among sites (β-diversity), indicating that sites are increasingly more alike to each other (i.e. increased biotic homogenization). …”

A Human Torque Teno Virus Encodes a MicroRNA That Inhibits Interferon Signaling by Rodney P. Kincaid (293245)

“…SiRNA knockdown of NMI contributes to a decreased response to interferon signaling. Consistent with this, we show that a TTV miRNA mediates a decreased response to IFN and increased cellular proliferation in the presence of IFN. …”

Diet Modification and Metformin Have a Beneficial Effect in a Fly Model of Obesity and Mucormycosis by Fazal Shirazi (413427)

“…<div><p>In an experimental model of obesity and hyperglycemia in <i>Drosophila melanogaster</i> we studied the effect of diet modification and administration of metformin on systemic infection with <i>Rhizopus</i>, a common cause of mucormycosis in diabetic patients. …”

XPS fitting of different forms of organic carbon in M0 (a), M1 (b), M2 (c), G0 (d), G1 (e) and G2 (f). by Shufeng Zhao (12820875)

Homogeneous groups for the occurrence of frequented item sets of web parts related to Pillar 3 for the quarter a) Q1, b) Q2, c) Q3 and d) Q4. by Anna Pilková (11614114)

DataSheet1_Simulations of graphite boronization: A molecular dynamics study of amorphization resulting from bombardment.docx by Aaditya Rau (13429605)

“…Simulations show that larger impact energies lead to a greater volume of amorphization and penetration of boron, but that the growth rate of the amorphous layer decreases with increasing fluence. …”

Illustration of a target concept (blue) spreading through a network, being affected by a boosting concept (green) on the left and an inhibiting concept (red) on the right. by James Archbold (5465150)

Proteomic analysis of Δ<i>flrA</i> and Δ<i>flaA</i>. by Mei Luo (773169)

“…Up-regulated/Down-regulated pathways indicate increased/decreased expression in Δ<i>flrA</i>. See supplementary information for a complete list with proteomic data. …”