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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
greater decrease » greater increase (Expand Search), greater increases (Expand Search), rate decreased (Expand Search)
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30421
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30423
Magnetic Resonance Imaging Cooling-Reheating Protocol Indicates Decreased Fat Fraction via Lipid Consumption in Suspected Brown Adipose Tissue
Published 2015“…<div><p>Objectives</p><p>To evaluate whether a water-fat magnetic resonance imaging (MRI) cooling-reheating protocol could be used to detect changes in lipid content and perfusion in the main human brown adipose tissue (BAT) depot after a three-hour long mild cold exposure.…”
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30424
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30425
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30426
Image_1_Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats.TIF
Published 2018“…Furthermore, SPN treatment prevents the degeneration of both cartilage and subchondral bone in a rat model of OA. To the best of our knowledge, this study is the first to report that SPN decreases interleukin-1β-induced inflammation in rat chondrocytes by inhibiting the activation of the NF-κB and wnt/β-catenin pathways, and, thus, has therapeutic potential in the treatment of OA.…”
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30427
Image_1_Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats.TIF
Published 2018“…Furthermore, SPN treatment prevents the degeneration of both cartilage and subchondral bone in a rat model of OA. To the best of our knowledge, this study is the first to report that SPN decreases interleukin-1β-induced inflammation in rat chondrocytes by inhibiting the activation of the NF-κB and wnt/β-catenin pathways, and, thus, has therapeutic potential in the treatment of OA.…”
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30428
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30429
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30430
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30431
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30432
Adverse events <sup>a</sup>.
Published 2024“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”
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30433
Homozygous deletion of <i>ERG251</i> leads to increased sensitivity to cell membrane and osmotic stress but decreased sensitivity to oxidative stress.
Published 2024“…<p><b>A</b>. Volcano plot for differentially expressed genes (log<sub>2</sub> fold change ≥ 1 or ≤-1 and adjusted <i>p</i>-value < 0.05) in the <i>erg251Δ/Δ</i> mutant compared to <i>ERG251/ERG251</i> in YPAD. …”
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30434
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30435
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30436
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30437
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30438
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30439
2-AAPA decreases H/R induced apoptosis in mitoNEET-KD cells and increases mitoNEET-protein despite KD.
Published 2016“…<p>(A) Western Blot analysis of activated caspase-3 revealed reduced apoptosis in 2-AAPA treated mitoNEET-KD cells to the same level seen in 2-AAPA treated HL-1 cells after H/R (n = 6). …”
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30440